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Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field,…

Optics · Physics 2014-05-02 Guoan Zheng , Roarke Horstmeyer , Changhuei Yang

Multiple light scattering hampers imaging objects in complex scattering media. Approaches used in real practices mainly aim to filter out multiple scattering obscuring the ballistic waves that travel straight through the scattering medium.…

Optical imaging plays a crucial role in advancing science and technology, enabling applications in fields ranging from biomedicine to astronomy. However, imaging through scattering media such as biological tissues, fog, or turbulent…

Scattering, especially multiple scattering, is a well known problem in imaging, ranging from astronomy to medicine. In particular it is often desirable to be able to perform non-invasive imaging through turbid and/or opaque media. Many…

Optics · Physics 2024-04-23 Harry Penketh , Jacopo Bertolotti

Imaging through thick scattering media presents significant challenges, particularly for three-dimensional (3D) applications. This manuscript demonstrates a novel scheme for single-image-enabled 3D imaging through such media, treating the…

Optics · Physics 2024-10-10 Long Pan , Yunan Wang , Yijie Lou , Xiaohua Feng

Optical imaging deep inside scattering media remains a fundamental problem in bio-imaging. While wavefront shaping has been shown to allow focusing of coherent light at depth, achieving it non-invasively remains a challenge. Various…

Optics · Physics 2019-12-24 Antoine Boniface , Baptiste Blochet , Jonathan Dong , Sylvain Gigan

Imaging through scattering media is encountered in many disciplines or sciences, ranging from biology, mesescopic physics and astronomy. But it is still a big challenge because light suffers from multiple scattering is such media and can be…

Neural and Evolutionary Computing · Computer Science 2017-08-29 Meng Lyu , Hao Wang , Guowei Li , Guohai Situ

The intricate nature of the brain necessitates the application of advanced probing techniques to comprehensively study and understand its working mechanisms. Neurophotonics offers minimally invasive methods to probe the brain using optics…

Optical imaging through scattering media is a fundamental challenge in many applications. Recently, substantial breakthroughs such as imaging through biological tissues and looking around corners have been obtained by the use of…

Optics · Physics 2020-07-09 Tomer Yeminy , Ori Katz

The ability to image through turbid media such as organic tissues, is a highly attractive prospect for biological and medical imaging. This is challenging however, due to the highly scattering properties of tissues which scramble the image…

Optics · Physics 2020-09-25 Jack Radford , Ashley Lyons , Francesco Tonolini , Daniele Faccio

While scattered light conveys most of the information we perceive, scattering may also distort that information before it reaches our detectors. The problem is acute in many applications, such as in high-resolution microscopy of biological…

Three-photon (3P) microscopy is getting traction due to its superior performance in deep tissues. Yet, aberrations and light scattering still pose one of the main limitations in the attainable depth ranges for high-resolution imaging. Here,…

Imaging an object embedded within a scattering medium requires the correction of complex sample-induced wave distortions. Existing approaches have been designed to resolve them by optimizing signal waves recorded in each 2D image. Here, we…

Optics · Physics 2022-10-17 Ye-Ryoung Lee , Dong-Young Kim , Yonghyeon Jo , Moonseok Kim , Wonshik Choi

We propose a nonlinear imaging scheme with undetected photons that overcomes the diffraction limit by transferring near-field information at one wavelength to far-field information of a correlated photon with a different wavelength…

Quantum Physics · Physics 2022-05-11 Elkin A. Santos , Thomas Pertsch , Frank Setzpfandt , Sina Saravi

Traditional optical imaging systems can provide high-quality imaging with complicated and expensive optical design by eliminating aberrations. With the help of optical memory effect (ME), not independently improving single imaging…

Optics · Physics 2021-08-04 Fu Zhao , Shuman Du , Dong Liang , Jun Liu

In most biological tissues, light scattering due to small differences in refractive index limits the depth of optical imaging systems. Two-photon microscopy (2PM), which significantly reduces the scattering of the excitation light, has…

Far-field super-resolution fluorescence microscopy has been rapidly developed for applications ranging from cell biology to nanomaterials. However, it remains a significant challenge to achieve super-resolution imaging at depth in opaque…

Optics · Physics 2024-05-01 Tengfei Wu , YoonSeok Baek , Fei Xia , Sylvain Gigan , Hilton B. de Aguiar

Focusing waves inside inhomogeneous media is a fundamental problem for imaging. Spatial variations of wave velocity can strongly distort propagating wavefronts and degrade image quality. Adaptive focusing can compensate for such aberration,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 William Lambert , Laura A. Cobus , Thomas Frappart , Mathias Fink , Alexandre Aubry

Non-invasive optical focusing inside scattering media is still a big challenge because inhomogeneous media scatter both incoming photons for focusing and outgoing photons for observation. Various approaches, utilizing non-linear…

Optics · Physics 2021-09-17 Dayan Li , Sujit Kumar Sahoo , Huy Quoc Lam , Dong Wang , Cuong Dang