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Standard contrastive learning approaches usually require a large number of negatives for effective unsupervised learning and often exhibit slow convergence. We suspect this behavior is due to the suboptimal selection of negatives used for…

Machine Learning · Computer Science 2021-12-22 Anshul Shah , Suvrit Sra , Rama Chellappa , Anoop Cherian

Mitochondria segmentation in electron microscopy images is essential in neuroscience. However, due to the image degradation during the imaging process, the large variety of mitochondrial structures, as well as the presence of noise,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Zhili Li , Xuejin Chen , Jie Zhao , Zhiwei Xiong

High-content screening (HCS) assays based on high-throughput microscopy techniques such as Cell Painting have enabled the interrogation of cells' morphological responses to perturbations at an unprecedented scale. The collection of such…

Machine Learning · Computer Science 2025-09-25 Mingyu Lu , Ethan Weinberger , Chanwoo Kim , Su-In Lee

Microscopy images are powerful tools and widely used in the majority of research areas, such as biology, chemistry, physics and materials fields by various microscopies (scanning electron microscope (SEM), atomic force microscope (AFM) and…

Computer Vision and Pattern Recognition · Computer Science 2020-02-25 Israel Goytom , Qin Wang , Tianxiang Yu , Kunjie Dai , Kris Sankaran , Xinfei Zhou , Dongdong Lin

Contrastive self-supervised learning has attracted significant research attention recently. It learns effective visual representations from unlabeled data by embedding augmented views of the same image close to each other while pushing away…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Yichen Zhang , Yifang Yin , Ying Zhang , Roger Zimmermann

This paper proposes an efficient system for classifying cervical cancer cells using pre-trained convolutional neural networks (CNNs). We first fine-tune five pre-trained CNNs and minimize the overall cost of misclassification by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Ashfiqun Mustari , Rushmia Ahmed , Afsara Tasnim , Jakia Sultana Juthi , G M Shahariar

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

Resolving arterial flows is essential for understanding cardiovascular pathologies, improving diagnosis, and monitoring patient condition. Ultrasound contrast imaging uses microbubbles to enhance the scattering of the blood pool, allowing…

Nowadays, deep learning can be employed to a wide ranges of fields including medicine, engineering, etc. In deep learning, Convolutional Neural Network (CNN) is extensively used in the pattern and sequence recognition, video analysis,…

Computer Vision and Pattern Recognition · Computer Science 2019-02-06 Rezoana Bente Arif , Md. Abu Bakr Siddique , Mohammad Mahmudur Rahman Khan , Mahjabin Rahman Oishe

Traditional supervised learning with deep neural networks requires a tremendous amount of labelled data to converge to a good solution. For 3D medical images, it is often impractical to build a large homogeneous annotated dataset for a…

Coded-illumination can enable quantitative phase microscopy of transparent samples with minimal hardware requirements. Intensity images are captured with different source patterns and a non-linear phase retrieval optimization reconstructs…

Signal Processing · Electrical Eng. & Systems 2019-02-07 Michael R. Kellman , Emrah Bostan , Nicole Repina , Laura Waller

Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

Analysis-by-synthesis has been a successful approach for many tasks in computer vision, such as 6D pose estimation of an object in an RGB-D image which is the topic of this work. The idea is to compare the observation with the output of a…

Computer Vision and Pattern Recognition · Computer Science 2015-08-20 Alexander Krull , Eric Brachmann , Frank Michel , Michael Ying Yang , Stefan Gumhold , Carsten Rother

The growing use of convolutional neural networks (CNN) for a broad range of visual tasks, including tasks involving fine details, raises the problem of applying such networks to a large field of view, since the amount of computations…

Computer Vision and Pattern Recognition · Computer Science 2018-04-11 Hadar Gorodissky , Daniel Harari , Shimon Ullman

Contrastive learning and self-supervised techniques have gained prevalence in computer vision for the past few years. It is essential for medical image analysis, which is often notorious for its lack of annotations. Most existing…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Jun Li , Quan Quan , S. Kevin Zhou

Microscopy enables direct observation of cellular morphology in 3D, with transmitted-light methods offering low-cost, minimally invasive imaging and fluorescence microscopy providing specificity and contrast. Virtual staining combines these…

Machine learning (ML) tools such as encoder-decoder convolutional neural networks (CNN) can represent incredibly complex nonlinear functions which map between combinations of images and scalars. For example, CNNs can be used to map…

Machine Learning · Computer Science 2021-10-27 Alexander Scheinker

Machine learning is attracting surging interest across nearly all scientific areas by enabling the analysis of large datasets and the extraction of scientific information from incomplete data. Data-driven science is rapidly growing,…

Applied Physics · Physics 2025-03-17 Sung Yun Lee , Do Hyung Cho , Chulho Jung , Daeho Sung , Daewoong Nam , Sangsoo Kim , Changyong Song

Automated detection of cervical cancer cells or cell clumps has the potential to significantly reduce error rate and increase productivity in cervical cancer screening. However, most traditional methods rely on the success of accurate cell…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Yixiong Liang , Zhihong Tang , Meng Yan , Jialin Chen , Qing Liu , Yao Xiang

A convolutional neural network (CNN) is a deep learning algorithm that has been specifically designed for computer vision applications. The CNNs proved successful in handling the increasing amount of data in many computer vision problems,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Mustafa Yurdakul , Enes Ayan , Fahrettin Horasan , Sakir Tasdemir