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The rapidly evolving field of digital oncopathology faces significant challenges, including the need to address diverse and complex clinical questions, often involving rare conditions, with limited availability of labeled data. These…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Jonathan Zalach , Inbal Gazy , Assaf Avinoam , Ron Sinai , Eran Shmuel , Inbar Gilboa , Christine Swisher , Naim Matasci , Reva Basho , David B. Agus

This research presents an innovative approach to cancer diagnosis and prediction using explainable Artificial Intelligence (XAI) and deep learning techniques. With cancer causing nearly 10 million deaths globally in 2020, early and accurate…

Artificial Intelligence · Computer Science 2024-12-24 Badaru I. Olumuyiwa , The Anh Han , Zia U. Shamszaman

Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

Artificial intelligence (AI) is being deployed within radiology at a rapid pace. AI has proven an excellent tool for reconstructing and enhancing images that appear sharper, smoother, and more detailed, can be acquired more quickly, and…

Artificial Intelligence · Computer Science 2026-02-11 Jana G. Delfino , Jason L. Granstedt , Frank W. Samuelson , Robert Ochs , Krishna Juluru

Artificial intelligence holds great promise in medical imaging, especially histopathological imaging. However, artificial intelligence algorithms cannot fully explain the thought processes during decision-making. This situation has brought…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Tuncay Yiğit , Nilgün Şengöz , Özlem Özmen , Jude Hemanth , Ali Hakan Işık

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Cancer has relational information residing at varying scales, modalities, and resolutions of the acquired data, such as radiology, pathology, genomics, proteomics, and clinical records. Integrating diverse data types can improve the…

Machine Learning · Computer Science 2024-07-29 Asim Waqas , Aakash Tripathi , Ravi P. Ramachandran , Paul Stewart , Ghulam Rasool

Artificial Intelligence (AI) has become an integral part of domains such as security, finance, healthcare, medicine, and criminal justice. Explaining the decisions of AI systems in human terms is a key challenge--due to the high complexity…

Artificial Intelligence · Computer Science 2019-11-25 Sheikh Rabiul Islam , William Eberle , Sheikh K. Ghafoor

The recent development of imaging and sequencing technologies enables systematic advances in the clinical study of lung cancer. Meanwhile, the human mind is limited in effectively handling and fully utilizing the accumulation of such…

Machine Learning · Computer Science 2022-03-29 Yawei Li , Xin Wu , Ping Yang , Guoqian Jiang , Yuan Luo

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Jia-Hong Huang

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Accessing high-quality, open-access dermatopathology image datasets for learning and cross-referencing is a common challenge for clinicians and dermatopathology trainees. To establish a comprehensive open-access dermatopathology dataset for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Ziyang Xu , Mingquan Lin , Yiliang Zhou , Zihan Xu , Seth J. Orlow , Shane A. Meehan , Alexandra Flamm , Ata S. Moshiri , Yifan Peng

The use of Artificial Intelligence (AI) in healthcare, including in caring for cancer survivors, has gained significant interest. However, gaps remain in our understanding of how such AI systems can provide care, especially for ethnic and…

Human-Computer Interaction · Computer Science 2024-08-20 Elaine Kong , Kuo-Ting , Huang , Aakash Gautam

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

Machine Learning · Computer Science 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

Skin cancer is one of the most prevalent and deadly forms of cancer worldwide, highlighting the critical importance of early detection and diagnosis in improving patient outcomes. Deep learning (DL) has shown significant promise in…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Runhao Liu , Ziming Chen , Guangzhen Yao , Peng Zhang

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

The intersection of Artificial Intelligence (AI) and neuroscience in Explainable AI (XAI) is pivotal for enhancing transparency and interpretability in complex decision-making processes. This paper explores the evolution of XAI…

Artificial Intelligence · Computer Science 2024-02-13 Yongchen Zhou , Richard Jiang