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All materials enter or exit the cell nucleus through nuclear pore complexes (NPCs), efficient transport devices that combine high selectivity and throughput. A central feature of this transport is the binding of cargo-carrying soluble…

Cell Behavior · Quantitative Biology 2015-06-26 A. Zilman , S. DiTalia , B. T. Chait , M. P Rout , M. O. Magnasco

Nuclear pore complexes (NPCs) mediate the exchange of materials between the nucleoplasm and cytoplasm, playing a key role in the separation of nucleic acids and proteins into their required compartments. The static structure of the NPC is…

Biomolecules · Quantitative Biology 2023-04-07 David Cowburn , Michael Rout

Recently, porphyrin units have been attached to graphene nanoribbons (Por-GNR) enabling a multitude of possible structures. Here we report first principles calculations of two prototypical, experimentally feasible, Por-GNR hybrids, one of…

Mesoscale and Nanoscale Physics · Physics 2022-10-26 Fei Gao , Rodrigo E. Menchón , Aran Garcia-Lekue , Mads Brandbyge

The Froggatt-Nielsen (FN) mechanism offers an elegant explanation for the observed masses and mixings of Standard Model fermions. In this work, we systematically study FN models in the lepton sector, identifying a broad range of charge…

High Energy Physics - Phenomenology · Physics 2025-12-17 Claudia Cornella , David Curtin , Gordan Krnjaic , Micah Mellors

Systems driven far from equilibrium may exhibit anomalous density fluctuations: active matter with orientational order display giant density fluctuations at large scale, while systems of interacting particles close to an absorbing phase…

Statistical Mechanics · Physics 2026-03-23 Sara Dal Cengio , Romain Mari , Eric Bertin

Understanding how transcription factors (TFs) regulate mammalian gene expression in space and time is a central topic in biology. To activate a gene, a TF has first to diffuse in the available space of the nucleus until it reaches a target…

Subcellular Processes · Quantitative Biology 2018-11-19 Maxime Woringer , Xavier Darzacq

The viscosity of the suspension consisting of fine particles dispersed in a Newtonian liquid diverges close to the jamming packing fraction. The contact microstructure in suspensions governs this macroscopic behavior in the vicinity of…

Soft Condensed Matter · Physics 2025-02-28 Armin Aminimajd , Joao Maia , Abhinendra Singh

Transport phenomena in clean ferromagnet-superconductor-ferromagnet (FSF) trilayers are studied theoretically for a general case of arbitrary orientation of in-plane magnetizations and interface transparencies. Generalized expressions for…

Superconductivity · Physics 2007-05-23 Milos Bozovic , Zoran Radovic

We study the Josephson transport through ferromagnetic insulators (FIs) by taking into account its band structure explicitly. In the case of the fully polarized FIs (FPFIs), we found the formation of a pi-junction and an atomic-scale 0-pi…

Mesoscale and Nanoscale Physics · Physics 2010-05-21 Shiro Kawabata , Yasuhiro Asano , Yukio Tanaka , Satoshi Kashiwaya

A recurring motif in gene regulatory networks is transcription factors (TFs) that regulate each other, and then bind to overlapping sites on DNA, where they interact and synergistically control transcription of a target gene. Here, we…

Molecular Networks · Quantitative Biology 2013-03-07 Sahand Hormoz

Functionalized nanoparticles (NPs) are complex objects present in a variety of systems ranging from synthetic grafted nanoparticles to viruses. The morphology and number of the decorating groups can vary widely between systems. Thus, the…

Mesoscale and Nanoscale Physics · Physics 2023-03-22 Daniela Moreno-Chaparro , Nicolas Moreno , Florencio Balboa-Usabiaga , Marco Ellero

Understanding the post-merger evolution of binary neutron star merger (BNSM) requires accurate modeling of neutrino transport and microphysics including neutrino flavor conversions. Many previous studies have suggested that fast flavor…

High Energy Astrophysical Phenomena · Physics 2025-07-28 Hiroki Nagakura , Kohsuke Sumiyoshi , Sho Fujibayashi , Yuichiro Sekiguchi , Masaru Shibata

The Neutron Transport Equation (NTE) describes the flux of neutrons through an inhomogeneous fissile medium. In this paper, we reconnect the NTE to the physical model of the spatial Markov branching process which describes the process of…

Probability · Mathematics 2020-03-18 Emma Horton , Andreas E. Kyprianou , Denis Villemonais

Recent studies have suggested that the Nuclear Pore Complex (NPC) plays a significant role in mechanotransduction. When a force is exerted, the NPC's diameter widens, leading to an increased molecular flux into the nucleus. In this study,…

Biological Physics · Physics 2025-04-09 Atsushi Matsuda , Mohammad R. K. Mofrad

Fast neutrino flavor conversions (FFCs) and collisional flavor instabilities (CFIs) potentially affect the dynamics of core-collapse supernovae (CCSNe) and binary neutron star mergers (BNSMs). Under the assumption of homogeneous neutrinos,…

High Energy Astrophysical Phenomena · Physics 2023-07-19 Chinami Kato , Hiroki Nagakura , Masamichi Zaizen

Collective oscillations in dense neutrino gases (flavor waves) are notable for their instabilities that cause fast flavor conversion. We develop a quantum theory of interacting neutrinos and flavor wave quanta, which are analogous to…

High Energy Physics - Phenomenology · Physics 2025-06-03 Damiano F. G. Fiorillo , Georg G. Raffelt

Nuclear pore complexes are constantly confronted by large fluxes of macromolecules and macromolecular complexes that need to get into and out of the nucleus. Such bi-directional traffic occurring in a narrow channel can easily lead to…

Biological Physics · Physics 2008-07-22 Ruti Kapon , Alon Topchik , David Mukamel , and Ziv Reich

The quantum kinetic evolution of neutrinos in dense environments, such as the core-collapse supernovae or the neutron star mergers, can result in fast flavor conversion (FFC), presenting a significant challenge to achieving robust…

High Energy Astrophysical Phenomena · Physics 2025-02-10 Zewei Xiong , Meng-Ru Wu , Manu George , Chun-Yu Lin

Functional connectivity (FC) between brain regions tracks symptom severity in many neuropsychiatric disorders. Transcranial magnetic stimulation (TMS) directly alters regional activity and indirectly alters FC. Predicting how FC will change…

Neurons and Cognition · Quantitative Biology 2022-08-25 Andrew C. Murphy , Romain Duprat , Theodore D. Satterthwaite , Desmond J. Oathes , Dani S. Bassett

We present a systematic study of fast neutrino-flavor conversion (FFC) with both small-scale and large-scale numerical simulations in spherical symmetry. We find that FFCs can, in general, reach a quasi-steady state, and these features in…

High Energy Astrophysical Phenomena · Physics 2023-04-12 Hiroki Nagakura , Masamichi Zaizen
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