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Molecular Dynamics (MD) simulations are a powerful tool for studying matter at the atomic scale. However, to simulate solids, an initial atomic structure is crucial for the successful execution of MD simulations, but can be difficult to…

Computational Physics · Physics 2024-11-27 Lars Dammann , Richard Kohns , Patrick Huber , Robert H. Meißner

Deep reinforcement learning (RL) is an optimization-driven framework for producing control strategies for general dynamical systems without explicit reliance on process models. Good results have been reported in simulation. Here we…

Systems and Control · Electrical Eng. & Systems 2022-01-14 Nathan P. Lawrence , Michael G. Forbes , Philip D. Loewen , Daniel G. McClement , Johan U. Backstrom , R. Bhushan Gopaluni

Reinforcement learning (RL) often necessitates a meticulous Markov Decision Process (MDP) design tailored to each task. This work aims to address this challenge by proposing a systematic approach to behavior synthesis and control for…

Robotics · Computer Science 2024-10-18 Jean-Pierre Sleiman , Mayank Mittal , Marco Hutter

This study introduces the P5 model - a foundational method that utilizes reinforcement learning (RL) to augment control, effectiveness, and scalability in molecular dynamics simulations (MD). Our innovative strategy optimizes the sampling…

Machine Learning · Computer Science 2023-07-25 Paloma Gonzalez-Rojas , Andrew Emmel , Luis Martinez , Neil Malur , Gregory Rutledge

Improving the generalization ability of modern deep neural networks (DNNs) is a fundamental challenge in machine learning. Two branches of methods have been proposed to seek flat minima and improve generalization: one led by sharpness-aware…

Machine Learning · Computer Science 2024-04-02 Tao Li , Qinghua Tao , Weihao Yan , Zehao Lei , Yingwen Wu , Kun Fang , Mingzhen He , Xiaolin Huang

Accurate and efficient prediction of polymer properties is of key importance for polymer design. Traditional experimental tools and density function theory (DFT)-based simulations for polymer property evaluation, are both expensive and…

Materials Science · Physics 2024-10-08 Cong Shen , Yipeng Zhang , Fei Han , Kelin Xia

This article presents a motion planning and control framework for flexible robotic manipulators, integrating deep reinforcement learning (DRL) with a nonlinear partial differential equation (PDE) controller. Unlike conventional approaches…

Robotics · Computer Science 2025-06-11 Amir Hossein Barjini , Seyed Adel Alizadeh Kolagar , Sadeq Yaqubi , Jouni Mattila

We present a deep reinforcement learning (deep RL) algorithm that consists of learning-based motion planning and imitation to tackle challenging control problems. Deep RL has been an effective tool for solving many high-dimensional…

Robotics · Computer Science 2023-03-02 Nitish Sontakke , Sehoon Ha

Combining reinforcement learning (RL) and molecular dynamics (MD) simulations, we propose a machine-learning approach (RL$^\ddag$) to automatically unravel chemical reaction mechanisms. In RL$^\ddag$, locating the transition state of a…

Chemical Physics · Physics 2021-03-19 Jun Zhang , Yao-Kun Lei , Zhen Zhang , Xu Han , Maodong Li , Lijiang Yang , Yi Isaac Yang , Yi Qin Gao

The development of the DRL model for malware attribution involved extensive research, iterative coding, and numerous adjustments based on the insights gathered from predecessor models and contemporary research papers. This preparatory work…

Cryptography and Security · Computer Science 2025-01-08 Animesh Singh Basnet , Mohamed Chahine Ghanem , Dipo Dunsin , Wiktor Sowinski-Mydlarz

Automating molecular design using deep reinforcement learning (RL) has the potential to greatly accelerate the search for novel materials. Despite recent progress on leveraging graph representations to design molecules, such methods are…

Machine Learning · Statistics 2021-06-08 Gregor N. C. Simm , Robert Pinsler , Gábor Csányi , José Miguel Hernández-Lobato

Reinforcement learning (RL) has emerged as a promising approach to automating decision processes. This paper explores the application of RL techniques to optimise the polynomial order in the computational mesh when using high-order solvers.…

Machine Learning · Computer Science 2023-06-16 David Huergo , Gonzalo Rubio , Esteban Ferrer

We propose a deep reinforcement learning (DRL) methodology for the tracking, obstacle avoidance, and formation control of nonholonomic robots. By separating vision-based control into a perception module and a controller module, we can train…

Robotics · Computer Science 2019-11-19 Yanlin Zhou , Fan Lu , George Pu , Xiyao Ma , Runhan Sun , Hsi-Yuan Chen , Xiaolin Li , Dapeng Wu

In representation learning (RL), how to make the learned representations easy to interpret and less overfitted to training data are two important but challenging issues. To address these problems, we study a new type of regulariza- tion…

Machine Learning · Computer Science 2017-11-28 Pengtao Xie , Hongbao Zhang , Eric P. Xing

Deep reinforcement learning (RL) has made it possible to solve complex robotics problems using neural networks as function approximators. However, the policies trained on stationary environments suffer in terms of generalization when…

Robotics · Computer Science 2021-11-09 Aditya M. Deshpande , Ali A. Minai , Manish Kumar

Current end-to-end deep Reinforcement Learning (RL) approaches require jointly learning perception, decision-making and low-level control from very sparse reward signals and high-dimensional inputs, with little capability of incorporating…

Machine Learning · Computer Science 2019-10-10 Vibhavari Dasagi , Robert Lee , Serena Mou , Jake Bruce , Niko Sünderhauf , Jürgen Leitner

Prediction for ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) plays a crucial role in drug discovery and development, accelerating the screening and optimization of new drugs. Existing methods primarily rely on…

Machine Learning · Computer Science 2025-09-08 Han Zhang , Fengji Ma , Jiamin Su , Xinyue Yang , Lei Wang , Wen-Cai Ye , Li Liu

A variety of autonomous navigation algorithms exist that allow robots to move around in a safe and fast manner. However, many of these algorithms require parameter re-tuning when facing new environments. In this paper, we propose PTDRL, a…

Robotics · Computer Science 2023-06-21 Elias Goldsztejn , Tal Feiner , Ronen Brafman

Learning a predictive model of the mean return, or value function, plays a critical role in many reinforcement learning algorithms. Distributional reinforcement learning (DRL) has been shown to improve performance by modeling the value…

Machine Learning · Computer Science 2025-07-08 Ju-Seung Byun , Andrew Perrault

Quantum control requires high-precision and robust control pulses to ensure optimal system performance. However, control sequences generated with a system model may suffer from model bias, leading to low fidelity. While model-free…