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We consider the task of discovering gene regulatory networks, which are defined as sets of genes and the corresponding transcription factors which regulate their expression levels. This can be viewed as a variable selection problem,…

Methodology · Statistics 2014-12-04 Justin Bleich , Adam Kapelner , Edward I. George , Shane T. Jensen

We present a new approach to 3D object representation where a neural network encodes the geometry of an object directly into the weights and biases of a second 'mapping' network. This mapping network can be used to reconstruct an object by…

Machine Learning · Computer Science 2020-04-07 Eric Mitchell , Selim Engin , Volkan Isler , Daniel D Lee

Recent years have witnessed the rapid emergence of 3D Gaussian splatting (3DGS) as a powerful approach for 3D reconstruction and novel view synthesis. Its explicit representation with Gaussian primitives enables fast training, real-time…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Haato Watanabe , Nobuyuki Umetani

Modeling the preferences of agents over a set of alternatives is a principal concern in many areas. The dominant approach has been to find a single reward/utility function with the property that alternatives yielding higher rewards are…

Machine Learning · Computer Science 2022-06-09 Alihan Hüyük , William R. Zame , Mihaela van der Schaar

Deformable retinal image registration is notoriously difficult due to large homogeneous regions and sparse but critical vascular features, which cause limited gradient signals in standard learning-based frameworks. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xin Tian , Jiazheng Wang , Yuxi Zhang , Xiang Chen , Renjiu Hu , Gaolei Li , Min Liu , Hang Zhang

We investigate a learning decision support system for vehicle routing, where the routing engine learns implicit preferences that human planners have when manually creating route plans (or routings). The goal is to use these learned…

Artificial Intelligence · Computer Science 2021-01-12 Rocsildes Canoy , Víctor Bucarey , Jayanta Mandi , Tias Guns

Insightful visualization of multidimensional scalar fields, in particular parameter spaces, is key to many fields in computational science and engineering. We propose a principal component-based approach to visualize such fields that…

Graphics · Computer Science 2018-09-12 Rafael Ballester-Ripoll , Renato Pajarola

We develop a neurogeometric model for the arm area of motor cortex, which encodes complex motor primitives, ranging from simple movement features like movement direction, to short hand trajectories, termed fragments, and ultimately to more…

Neurons and Cognition · Quantitative Biology 2026-02-13 Caterina Mazzetti , Jawad Ali , Alessandro Sarti , Giovanna Citti

This Dissertation is comprised of two main projects, addressing questions in neuroscience through applications of generative modeling. Project #1 (Chapter 4) explores how neurons encode features of the external world. I combine Helmholtz's…

Neurons and Cognition · Quantitative Biology 2024-12-31 Hadi Vafaii

Convolutional neural networks have many hyperparameters such as the filter size, number of filters, and pooling size, which require manual tuning. Though deep stacked structures are able to create multi-scale and hierarchical…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Ilker Cam , F. Boray Tek

Drawing on recent breakthroughs in cellular neurobiology and detailed biophysical modeling linking neocortical pyramidal neurons to distinct mental-state regimes, this work introduces a mathematically grounded formulation showing how models…

Machine Learning · Computer Science 2026-03-17 Ahsan Adeel , M. Bilal

We study Gabor orthonormal windows in $L^2({\Bbb Z}_p^d)$ for translation and modulation sets $A$ and $B$, respectively, where $p$ is prime and $d\geq 2$. We prove that for a set $E\subset \Bbb Z_p^d$, the indicator function $1_E$ is a…

Classical Analysis and ODEs · Mathematics 2017-12-27 A. Iosevich , M. Kolountzakis , Yu. Lyubarskii , A. Mayeli , J. Pakianathan

Recent advancements in model-free deep reinforcement learning have enabled efficient agent training. However, challenges arise when determining the region of attraction for these controllers, especially if the region does not fully cover…

Systems and Control · Electrical Eng. & Systems 2024-09-04 Armin Ghanbarzadeh , Esmaeil Najafi

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Jakob Wasserthal , Peter F. Neher , Klaus H. Maier-Hein

Visual segmentation is a key perceptual function that partitions visual space and allows for detection, recognition and discrimination of objects in complex environments. The processes underlying human segmentation of natural images are…

Computer Vision and Pattern Recognition · Computer Science 2019-05-03 Jonathan Vacher , Pascal Mamassian , Ruben Coen-Cagli

Recently, many convolutional neural network (CNN) methods have been designed for hyperspectral image (HSI) classification since CNNs are able to produce good representations of data, which greatly benefits from a huge number of parameters.…

Image and Video Processing · Electrical Eng. & Systems 2020-02-25 Chenying Liu , Jun Li , Lin He , Antonio J. Plaza , Shutao Li , Bo Li

Cerebellar-like networks, in which input activity patterns are separated by projection to a much higher-dimensional space before classification, are a recurring neurobiological motif, present in the cerebellum, dentate gyrus, insect…

Neurons and Cognition · Quantitative Biology 2026-03-23 William Dorrell , Peter E. Latham

The structure tensor method is often used for 2D and 3D analysis of imaged structures, but its results are in many cases very dependent on the user's choice of method parameters. We simplify this parameter choice in first order structure…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Pawel Tomasz Pieta , Anders Bjorholm Dahl , Jeppe Revall Frisvad , Siavash Arjomand Bigdeli , Anders Nymark Christensen

The human brain represents objects in a way that is both invariant across instances and flexible enough to support different contexts and tasks. Yet it remains unknown how object representations are dynamically remapped as the same object…

Neurons and Cognition · Quantitative Biology 2026-05-27 Julien Dirani , Shankar Chawla , Leila Wehbe , Bradford Z. Mahon

The local fiber orientation is a micro-structural feature crucial for the mechanical properties of parts made from fiber reinforced polymers. It can be determined from micro-computed tomography data and subsequent quantitative analysis of…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Thomas Baranowski , Dascha Dobrovolskij , Kilian Dremel , Astrid Hölzing , Günter Lohfink , Katja Schladitz , Simon Zabler