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Early detection of cancerous tissue is crucial for long-term patient survival. In the head and neck region, a typical diagnostic procedure is an endoscopic intervention where a medical expert manually assesses tissue using RGB camera…
We explore a solution for learning disease signatures from weakly, yet easily obtainable, annotated volumetric medical imaging data by analyzing 3D volumes as a sequence of 2D images. We demonstrate the performance of our solution in the…
The Segment Anything Model (SAM) has achieved remarkable successes in the realm of natural image segmentation, but its deployment in the medical imaging sphere has encountered challenges. Specifically, the model struggles with medical…
In this work, we review previously developed coarse-grained (CG) particle models for biological membrane and red blood cells (RBCs) and discuss the advantages of the CG particle method over the continuum and atomic simulations on modeling…
Ambulatory blood pressure monitoring (ABPM) enables continuous measurement of blood pressure and heart rate over 24 hours and is increasingly used in clinical studies. However, ABPM data are often reduced to summary statistics, such as…
During clinical practice, radiologists often use attributes, e.g. morphological and appearance characteristics of a lesion, to aid disease diagnosis. Effectively modeling attributes as well as all relationships involving attributes could…
The main focus of image mining in the proposed method is concerned with the classification of brain tumor in the CT scan brain images. The major steps involved in the system are: pre-processing, feature extraction, association rule mining…
Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…
Aggregates of misfolded tau proteins (or just 'tau' for brevity) play a crucial role in the progression of Alzheimer's disease (AD) as they correlate with cell death and accelerated tissue atrophy. Longitudinal positron emission tomography…
Purpose: The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback during interventions, real-time in-vivo imaging with confocal laser microscopy has…
Purpose: Arterial Spin Labeling (ASL) is a quantitative, non-invasive alternative to perfusion imaging with contrast agents. Fixing values of certain model parameters in traditional ASL, which actually vary from region to region, may…
Histopathology image segmentation is essential for delineating tissue structures in skin cancer diagnostics, but modeling spatial context and inter-tissue relationships remains a challenge, especially in regions with overlapping or…
Marking anatomical landmarks in cephalometric radiography is a critical operation in cephalometric analysis. Automatically and accurately locating these landmarks is a challenging issue because different landmarks require different levels…
Compressing and expanding (companding) HDR computerized tomography (CT) images to a single LDR image is still a relevant challenge. Besides the general need for simplification of the window setting method for the purpose of diagnosis, there…
Poor resolution of ultrasound images due to convolution of the tissue reflectivity function (TRF) with the system point spread function (PSF) is a major issue in medical ultrasound imaging. In this paper, we propose a correlation…
Ultrasound is an adjunct tool to mammography that can quickly and safely aid physicians with diagnosing breast abnormalities. Clinical ultrasound often assumes a constant sound speed to form B-mode images for diagnosis. However, the various…
Imaging demonstrates that preclinical and human tumors are heterogeneous, i.e. a single tumor can exhibit multiple regions that behave differently during both normal development and also in response to treatment. The large variations…
Cardiac motion estimation is an important diagnostic tool to detect heart diseases and it has been explored with modalities such as MRI and conventional ultrasound (US) sequences. US cardiac motion estimation still presents challenges…
The newly released Segment Anything Model (SAM) is a popular tool used in image processing due to its superior segmentation accuracy, variety of input prompts, training capabilities, and efficient model design. However, its current model is…
We propose a novel approach to parameter estimation for simulator-based statistical models with intractable likelihood. Our proposed method involves recursive application of kernel ABC and kernel herding to the same observed data. We…