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Genome sequencing technology has advanced at a rapid pace and it is now possible to generate highly-detailed genotypes inexpensively. The collection and analysis of such data has the potential to support various applications, including…

Cryptography and Security · Computer Science 2015-06-18 Muhammad Naveed , Erman Ayday , Ellen W. Clayton , Jacques Fellay , Carl A. Gunter , Jean-Pierre Hubaux , Bradley A. Malin , XiaoFeng Wang

The cost of DNA sequencing has resulted in a surge of genetic data being utilised to improve scientific research, clinical procedures, and healthcare delivery in recent years. Since the human genome can uniquely identify an individual, this…

Cryptography and Security · Computer Science 2022-02-11 Sara Jafarbeiki , Raj Gaire , Amin Sakzad , Shabnam Kasra Kermanshahi , Ron Steinfeld

Recent advances in DNA sequencing technologies have put ubiquitous availability of fully sequenced human genomes within reach. It is no longer hard to imagine the day when everyone will have the means to obtain and store one's own DNA…

Cryptography and Security · Computer Science 2015-03-19 Pierre Baldi , Roberta Baronio , Emiliano De Cristofaro , Paolo Gasti , Gene Tsudik

We are entering the era of ubiquitous genetic information for research, clinical care, and personal curiosity. Sharing these datasets is vital for rapid progress in understanding the genetic basis of human diseases. However, one growing…

Genomics · Quantitative Biology 2013-10-14 Yaniv Erlich , Arvind Narayanan

Over the past several years, DNA sequencing has emerged as one of the driving forces in life-sciences, paving the way for affordable and accurate whole genome sequencing. As genomes represent the entirety of an organism's hereditary…

Cryptography and Security · Computer Science 2015-02-17 Emiliano De Cristofaro

Human genomic data carry unique information about an individual and offer unprecedented opportunities for healthcare. The clinical interpretations derived from large genomic datasets can greatly improve healthcare and pave the way for…

Cryptography and Security · Computer Science 2022-09-19 Mohammed Alghazwi , Fatih Turkmen , Joeri van der Velde , Dimka Karastoyanova

Machine learning can have major societal impact in computational biology applications. In particular, it plays a central role in the development of precision medicine, whereby treatment is tailored to the clinical or genetic features of the…

Computers and Society · Computer Science 2018-09-05 Chloé-Agathe Azencott

The genome is a unique identifier for human individuals. The genome also contains highly sensitive information, creating a high potential for misuse of genomic data (for example, genetic discrimination). In this paper, I investigated how…

Cryptography and Security · Computer Science 2017-01-12 Isabel Wagner

The data revolution holds significant promise for the health sector. Vast amounts of data collected from individuals will be transformed into knowledge, AI models, predictive systems, and best practices. One area of health that stands to…

Cryptography and Security · Computer Science 2024-07-15 Zahra Rahmani , Nahal Shahini , Nadav Gat , Zebin Yun , Yuzhou Jiang , Ofir Farchy , Yaniv Harel , Vipin Chaudhary , Mahmood Sharif , Erman Ayday

Novel technologies in genomics allow creating data in exascale dimension with relatively minor effort of human and laboratory and thus monetary resources compared to capabilities only a decade ago. While the availability of this data…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-11-10 Sandra Gesing , Thomas Richard Connor , Ian Taylor

In recent years, Whole Genome Sequencing (WGS) evolved from a futuristic-sounding research project to an increasingly affordable technology for determining complete genome sequences of complex organisms, including humans. This prompts a…

Cryptography and Security · Computer Science 2015-02-17 Erman Ayday , Emiliano De Cristofaro , Jean-Pierre Hubaux , Gene Tsudik

Artificial intelligence (AI) has been successfully applied in numerous scientific domains. In biomedicine, AI has already shown tremendous potential, e.g. in the interpretation of next-generation sequencing data and in the design of…

In recent years, the amount of information collected about human beings has increased dramatically. This development has been partially driven by individuals posting and storing data about themselves and friends using online social networks…

Computers and Society · Computer Science 2014-03-24 Arkadiusz Stopczynski , Riccardo Pietri , Alex Pentland , David Lazer , Sune Lehmann

Progress in Whole Genome Sequencing (WGS) will soon allow a large number of individuals to have their genome fully sequenced. This lays the foundations to improve modern healthcare, enabling a new era of personalized medicine where…

Cryptography and Security · Computer Science 2014-02-03 Emiliano De Cristofaro

The digitization of health records has greatly improved the efficiency of the healthcare system and promoted the formulation of related research and policies. However, the widespread application of advanced technologies such as electronic…

Cryptography and Security · Computer Science 2025-02-07 Zhang Si Yuan , Manmeet Mahinderjit Singh

Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…

Genomics · Quantitative Biology 2018-11-28 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

The rapid growth in digital data forms the basis for a wide range of new services and research, e.g, large-scale medical studies. At the same time, increasingly restrictive privacy concerns and laws are leading to significant overhead in…

Cryptography and Security · Computer Science 2021-09-06 Bernardo A. Huberman , Tad Hogg

The eruption of big data with the increasing collection and processing of vast volumes and variety of data have led to breakthrough discoveries and innovation in science, engineering, medicine, commerce, criminal justice, and national…

Cryptography and Security · Computer Science 2020-07-03 Fang Liu
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