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Human cancers present a significant public health challenge and require the discovery of novel drugs through translational research. Transcriptomics profiling data that describes molecular activities in tumors and cancer cell lines are…

We introduce an online neural sequence to sequence model that learns to alternate between encoding and decoding segments of the input as it is read. By independently tracking the encoding and decoding representations our algorithm permits…

Computation and Language · Computer Science 2016-09-28 Lei Yu , Jan Buys , Phil Blunsom

Cyclic coordinate descent is a classic optimization method that has witnessed a resurgence of interest in machine learning. Reasons for this include its simplicity, speed and stability, as well as its competitive performance on $\ell_1$…

Machine Learning · Computer Science 2015-03-17 Ankan Saha , Ambuj Tewari

Processing high-throughput DNA sequencing data of individuals or populations requires stringing together independent software tools with many parameters, often leading to non-reproducible pipelines and datasets. We developed grenepipe to…

Genomics · Quantitative Biology 2025-01-09 Lucas Czech , Moises Exposito-Alonso

We consider distributed plurality consensus in a complete graph of size $n$ with $k$ initial opinions. We design an efficient and simple protocol in the asynchronous communication model that ensures that all nodes eventually agree on the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-02-23 Robert Elsässer , Tom Friedetzky , Dominik Kaaser , Frederik Mallmann-Trenn , Horst Trinker

The voting method, an ensemble approach for fundamental frequency estimation, is empirically known for its robustness but lacks thorough investigation. This paper provides a principled analysis and improvement of this technique. First, we…

Sound · Computer Science 2026-02-03 Junya Koguchi , Tomoki Koriyama

Previous studies have shown that automated text-mining tools are becoming increasingly important for successfully unlocking variant information in scientific literature at large scale. Despite multiple attempts in the past, existing tools…

Computation and Language · Computer Science 2022-04-08 Chih-Hsuan Wei , Alexis Allot , Kevin Riehle , Aleksandar Milosavljevic , Zhiyong Lu

Convolutional neural networks (CNNs) are widely applied in real-time applications on resource-constrained devices. To accelerate CNN inference, prior works proposed to distribute the inference workload across multiple devices. However, they…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-14 Xing Liu , Chao Huang , Ming Tang

Sampling is a basic operation in many inference-time algorithms of large language models (LLMs). To scale up inference efficiently with a limited compute, it is crucial to find an optimal allocation for sample compute budgets: Which…

Computation and Language · Computer Science 2024-10-31 Kexun Zhang , Shang Zhou , Danqing Wang , William Yang Wang , Lei Li

We introduce Logical Offline Cycle Consistency Optimization (LOCCO), a scalable, semi-supervised method for training a neural semantic parser. Conceptually, LOCCO can be viewed as a form of self-learning where the semantic parser being…

Computation and Language · Computer Science 2023-06-01 Maxwell Crouse , Ramon Astudillo , Tahira Naseem , Subhajit Chaudhury , Pavan Kapanipathi , Salim Roukos , Alexander Gray

Consensus clustering (or clustering aggregation) inputs $k$ partitions of a given ground set $V$, and seeks to create a single partition that minimizes disagreement with all input partitions. State-of-the-art algorithms for consensus…

Data Structures and Algorithms · Computer Science 2023-07-11 Nathan Cordner , George Kollios

Discontinuous constituent parsers have always lagged behind continuous approaches in terms of accuracy and speed, as the presence of constituents with discontinuous yield introduces extra complexity to the task. However, a discontinuous…

Computation and Language · Computer Science 2021-09-14 Daniel Fernández-González , Carlos Gómez-Rodríguez

Evolution in its course found a variety of solutions to the same optimisation problem. The advent of high-throughput genomic sequencing has made available extensive data from which, in principle, one can infer the underlying structure on…

Quantitative Methods · Quantitative Biology 2016-04-12 Silvia Grigolon , Silvio Franz , Matteo Marsili

Today, machine learning tools, particularly artificial neural networks, have become crucial for diverse applications. However, current digital computing tools to train and deploy artificial neural networks often struggle with massive data…

Emerging Technologies · Computer Science 2025-02-14 Bora Çarpınlıoğlu , Uğur Teğin

Hacking and false data injection from adversaries can threaten power grids' everyday operations and cause significant economic loss. Anomaly detection in power grids aims to detect and discriminate anomalies caused by cyber attacks against…

Machine Learning · Computer Science 2023-03-14 Xijuan Sun , Di Wu , Arnaud Zinflou , Benoit Boulet

Computational methods for discovering patterns of local correlations in sequences are important in computational biology. Here we show how to determine the optimal partitioning of aligned sequences into non-overlapping segments such that…

Computational Engineering, Finance, and Science · Computer Science 2012-06-26 Joseph Bockhorst , Nebojsa Jojic

Conic programming has well-documented merits in a gamut of signal processing and machine learning tasks. This contribution revisits a recently developed first-order conic descent (CD) solver, and advances it in three aspects: intuition,…

Optimization and Control · Mathematics 2023-08-16 Bingcong Li , Georgios B. Giannakis

In this work, we propose Retentive Network (RetNet) as a foundation architecture for large language models, simultaneously achieving training parallelism, low-cost inference, and good performance. We theoretically derive the connection…

Computation and Language · Computer Science 2023-08-10 Yutao Sun , Li Dong , Shaohan Huang , Shuming Ma , Yuqing Xia , Jilong Xue , Jianyong Wang , Furu Wei

A fast and efficient stochastic opposition-based learning (OBL) variant is proposed in this paper. OBL is a machine learning concept to accelerate the convergence of soft computing algorithms, which consists of simultaneously calculating an…

Neural and Evolutionary Computing · Computer Science 2020-05-27 Tae Jong Choi , Julian Togelius , Yun-Gyung Cheong

Traditional orthogonal range problems allow queries over a static set of points, each with some value. Dynamic variants allow points to be added or removed, one at a time. To support more powerful updates, we introduce the Grid Range class…

Data Structures and Algorithms · Computer Science 2021-01-07 Joshua Lau , Angus Ritossa