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This study presents a novel deep learning architecture for multi-class classification and localization of abnormalities in medical imaging illustrated through experiments on mammograms. The proposed network combines two learning branches.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-14 Ran Bakalo , Jacob Goldberger , Rami Ben-Ari

Lung cancer remains one of the leading causes of morbidity and mortality worldwide, making early diagnosis critical for improving therapeutic outcomes and patient prognosis. Computer-aided diagnosis systems, which analyze computed…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Guohui Cai , Ying Cai , Zeyu Zhang , Yuanzhouhan Cao , Lin Wu , Daji Ergu , Zhinbin Liao , Yang Zhao

Since radiologists have different training and clinical experiences, they may provide various segmentation annotations for a lung nodule. Conventional studies choose a single annotation as the learning target by default, but they waste…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Han Yang , Lu Shen , Mengke Zhang , Qiuli Wang

Purpose: Lung nodules have very diverse shapes and sizes, which makes classifying them as benign/malignant a challenging problem. In this paper, we propose a novel method to predict the malignancy of nodules that have the capability to…

Computer Vision and Pattern Recognition · Computer Science 2019-04-24 Mundher Al-Shabi , Boon Leong Lan , Wai Yee Chan , Kwan-Hoong Ng , Maxine Tan

The state of the art lung nodule detection studies rely on computationally expensive multi-stage frameworks to detect nodules from CT scans. To address this computational challenge and provide better performance, in this paper we propose…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Naji Khosravan , Ulas Bagci

Image segmentation is a fundamental problem in medical image analysis. In recent years, deep neural networks achieve impressive performances on many medical image segmentation tasks by supervised learning on large manually annotated data.…

Computer Vision and Pattern Recognition · Computer Science 2018-01-26 Ling Zhang , Vissagan Gopalakrishnan , Le Lu , Ronald M. Summers , Joel Moss , Jianhua Yao

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Lung nodule classification is a class imbalanced problem, as nodules are found with much lower frequency than non-nodules. In the class imbalanced problem, conventional classifiers tend to be overwhelmed by the majority class and ignore the…

Computer Vision and Pattern Recognition · Computer Science 2017-12-19 Masaharu Sakamoto , Hiroki Nakano , Kun Zhao , Taro Sekiyama

Lung cancer is a leading cause of death worldwide and early screening is critical for improving survival outcomes. In clinical practice, the contextual structure of nodules and the accumulated experience of radiologists are the two core…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Jianpeng Zhang , Xianghua Ye , Jianfeng Zhang , Yuxing Tang , Minfeng Xu , Jianfei Guo , Xin Chen , Zaiyi Liu , Jingren Zhou , Le Lu , Ling Zhang

Lung cancer is the leading reason behind cancer-related deaths within the world. Early detection of lung nodules is vital for increasing the survival rate of cancer patients. Traditionally, physicians should manually identify the world…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Hasan Hejbari Zargar , Saha Hejbari Zargar , Raziye Mehri , Farzane Tajidini

Classifying chest radiographs is a time-consuming and challenging task, even for experienced radiologists. This provides an area for improvement due to the difficulty in precisely distinguishing between conditions such as pleural effusion,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Maria Efimovich , Jayden Lim , Vedant Mehta , Ethan Poon

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

In the first step, a pre-trained model (YOLO) was used to detect all suspicious nod-ules. The YOLO model was re-trained using 397 CT images to detect the entire nodule in CT images. To maximize the sensitivity of the model, a confidence…

Medical Physics · Physics 2022-12-20 Yashar Ahmadyar Razlighi , Alireza Kamali-Asl , Hossein Arabi

We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Kushal Mehta , Arshita Jain , Jayalakshmi Mangalagiri , Sumeet Menon , Phuong Nguyen , David R. Chapman

Accurate assessment of Lung nodules is a time consuming and error prone ingredient of the radiologist interpretation work. Automating 3D volume detection and segmentation can improve workflow as well as patient care. Previous works have…

Image and Video Processing · Electrical Eng. & Systems 2019-07-29 Evi Kopelowitz , Guy Engelhard

Accurate lung nodule segmentation is crucial for early-stage lung cancer diagnosis, as it can substantially enhance patient survival rates. Computed tomography (CT) images are widely employed for early diagnosis in lung nodule analysis.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-11 Muhammad Usman , Azka Rehman , Abd Ur Rehman , Abdullah Shahid , Tariq Mahmood Khan , Imran Razzak , Minyoung Chung , Yeong Gil Shin

Computer aided diagnostic (CAD) system is crucial for modern med-ical imaging. But almost all CAD systems operate on reconstructed images, which were optimized for radiologists. Computer vision can capture features that is subtle to human…

Computer Vision and Pattern Recognition · Computer Science 2018-10-04 Dufan Wu , Kyungsang Kim , Bin Dong , Georges El Fakhri , Quanzheng Li

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Early detection of malignant lung nodules remains constrained by size and growth based screening criteria, often delaying diagnosis. We present an integrated AI system that jointly performs nodule detection and malignancy assessment…

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