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Breast-Conserving Surgery (BCS) requires precise intraoperative margin assessment to preserve healthy tissue. Deep Ultraviolet Fluorescence Scanning Microscopy (DUV-FSM) offers rapid, high-resolution surface imaging for this purpose;…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Pouya Afshin , David Helminiak , Tianling Niu , Julie M. Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Speckle noise has long been an extensively studied problem in medical imaging. In recent years, there have been significant advances in leveraging deep learning methods for noise reduction. Nevertheless, adaptation of supervised learning…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Deborah Pereg

Data scarcity hinders deep learning for medical imaging. We propose a framework for breast cancer classification in thermograms that addresses this using a Diffusion Probabilistic Model (DPM) for data augmentation. Our DPM-based…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Sepehr Salem , M. Moein Esfahani , Jingyu Liu , Vince Calhoun

Limited-Angle Computed Tomography (LACT) is a non-destructive evaluation technique used in a variety of applications ranging from security to medicine. The limited angle coverage in LACT is often a dominant source of severe artifacts in the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Jiaming Liu , Rushil Anirudh , Jayaraman J. Thiagarajan , Stewart He , K. Aditya Mohan , Ulugbek S. Kamilov , Hyojin Kim

In this paper, we formulate the reconstruction problem in diffuse optical tomography (DOT) in a statistical setting for determining the optical parameters, scattering and absorption, from boundary photon density measurements. A special kind…

Numerical Analysis · Mathematics 2020-02-20 Thilo Strauss , Sanwar Ahmad , Taufiquar Khan

Characterizing statistical properties of solutions of inverse problems is essential for decision making. Bayesian inversion offers a tractable framework for this purpose, but current approaches are computationally unfeasible for most…

Machine Learning · Statistics 2024-12-18 Jonas Adler , Ozan Öktem

Recent research efforts in optical computing have gravitated towards developing optical neural networks that aim to benefit from the processing speed and parallelism of optics/photonics in machine learning applications. Among these…

Optics · Physics 2020-12-25 Deniz Mengu , Yair Rivenson , Aydogan Ozcan

Optical diffraction tomography (ODT) has emerged as a powerful label-free three-dimensional (3D) bioimaging techniques for observing living cells and thin tissue layers. We report a new reflection-mode ODT (rODT) method for imaging thick…

In optical diffraction tomography (ODT), the three-dimensional scattering potential of a microscopic object rotating around its center is recovered by a series of illuminations with coherent light. Reconstruction algorithms such as the…

Numerical Analysis · Mathematics 2022-09-02 Robert Beinert , Michael Quellmalz

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Zheren Li , Zhiming Cui , Lichi Zhang , Sheng Wang , Chenjin Lei , Xi Ouyang , Dongdong Chen , Xiangyu Zhao , Yajia Gu , Zaiyi Liu , Chunling Liu , Dinggang Shen , Jie-Zhi Cheng

A deep learning-assisted inversion method is proposed to solve the inhomogeneous background imaging problem. Three non-iterative methods, namely the distorted-Born (DB) major current coefficients method, the DB modified Born approximation…

Applied Physics · Physics 2023-12-12 Naike Du , Tiantian Yin , Jing Wang , Rencheng Song , Kuiwen Xu , Bingyuan Liang , Sheng Sun , Xiuzhu Ye

A method for reconstructing the direction of a fast neutron source using a segmented organic scintillator-based detector and deep learning model is proposed and analyzed. The model is based on recurrent neural network, which can be trained…

Instrumentation and Detectors · Physics 2023-01-27 Jun Woo Bae , Tingshiuan C. Wu , Igor Jovanovic

Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratissue and intracellular activities. Current DOCT methods, such…

Electrical Impedance Tomography (EIT) is a powerful imaging modality widely used in medical diagnostics, industrial monitoring, and environmental studies. The EIT inverse problem is about inferring the internal conductivity distribution of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-11 Alexander Denker , Fabio Margotti , Jianfeng Ning , Kim Knudsen , Derick Nganyu Tanyu , Bangti Jin , Andreas Hauptmann , Peter Maass

Line intensity mapping is emerging as a novel method that can measure the collective intensity fluctuations of atomic/molecular line emission from distant galaxies. Several observational programs with various wavelengths are ongoing and…

Astrophysics of Galaxies · Physics 2021-12-15 Kana Moriwaki , Naoki Yoshida

Untrained Physics-based Deep Learning (DL) methods for digital holography have gained significant attention due to their benefits, such as not requiring an annotated training dataset, and providing interpretability since utilizing the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Xiwen Chen , Hao Wang , Zhao Zhang , Zhenmin Li , Huayu Li , Tong Ye , Abolfazl Razi

Optical focusing at depths in tissue is the Holy Grail of biomedical optics that may bring revolutionary advancement to the field. Wavefront shaping is a widely accepted approach to solve this problem, but most implementations thus far have…

Applied Physics · Physics 2019-09-04 Yunqi Luo , Suxia Yan , Huanhao Li , Puxiang Lai , Yuanjin Zheng

Data transformations (e.g. rotations, reflections, and cropping) play an important role in self-supervised learning. Typically, images are transformed into different views, and neural networks trained on tasks involving these views produce…

Machine Learning · Computer Science 2022-02-04 Chen Qiu , Timo Pfrommer , Marius Kloft , Stephan Mandt , Maja Rudolph

End-to-end deep learning improves breast cancer classification on diffusion-weighted MR images (DWI) using a convolutional neural network (CNN) architecture. A limitation of CNN as opposed to previous model-based approaches is the…

We introduce a new computer aided detection and diagnosis system for lung cancer screening with low-dose CT scans that produces meaningful probability assessments. Our system is based entirely on 3D convolutional neural networks and…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Onur Ozdemir , Rebecca L. Russell , Andrew A. Berlin