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Multiple instance learning exhibits a powerful approach for whole slide image-based diagnosis in the absence of pixel- or patch-level annotations. In spite of the huge size of hole slide images, the number of individual slides is often…

The combination of tomographic imaging and deep learning, or machine learning in general, promises to empower not only image analysis but also image reconstruction. The latter aspect is considered in this perspective article with an…

Quantitative Methods · Quantitative Biology 2016-11-07 Ge Wang

Effective recognition of acute and difficult-to-heal wounds is a necessary step in wound diagnosis. An efficient classification model can help wound specialists classify wound types with less financial and time costs and also help in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ramin Mousa , Hadis Taherinia , Khabiba Abdiyeva , Amir Ali Bengari , Mohammadmahdi Vahediahmar

The field of computational pathology presents many challenges for computer vision algorithms due to the sheer size of pathology images. Histopathology images are large and need to be split up into image tiles or patches so modern…

Computer Vision and Pattern Recognition · Computer Science 2021-08-25 Rob Jewsbury , Abhir Bhalerao , Nasir Rajpoot

In a research context, image acquisition will often involve a pre-defined static protocol and the data will be of high quality. If we are to build applications that work in hospitals without significant operational changes in care delivery,…

Computer Vision and Pattern Recognition · Computer Science 2018-07-18 Thomas Varsavsky , Zach Eaton-Rosen , Carole H. Sudre , Parashkev Nachev , M. Jorge Cardoso

Although deep learning models like CNNs have achieved great success in medical image analysis, the small size of medical datasets remains a major bottleneck in this area. To address this problem, researchers have started looking for…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Xiaozheng Xie , Jianwei Niu , Xuefeng Liu , Zhengsu Chen , Shaojie Tang , Shui Yu

Computer-aided detection has been a research area attracting great interest in the past decade. Machine learning algorithms have been utilized extensively for this application as they provide a valuable second opinion to the doctors.…

Deep neural networks have proven to be very effective for computer vision tasks, such as image classification, object detection, and semantic segmentation -- these are primarily applied to color imagery and video. In recent years, there has…

Computer Vision and Pattern Recognition · Computer Science 2020-07-20 Xiong Zhou , Saurabh Prasad

Deep learning-based image processing is capable of creating highly appealing results. However, it is still widely considered as a "blackbox" transformation. In medical imaging, this lack of comprehensibility of the results is a sensitive…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 Bernhard Stimpel , Christopher Syben , Franziska Schirrmacher , Philipp Hoelter , Arnd Dörfler , Andreas Maier

Medical imaging is playing a more and more important role in clinics. However, there are several issues in different imaging modalities such as slow imaging speed in MRI, radiation injury in CT and PET. Therefore, accelerating MRI, reducing…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Jing Cheng , Haifeng Wang , Yanjie Zhu , Qiegen Liu , Qiyang Zhang , Ting Su , Jianwei Chen , Yongshuai Ge , Zhanli Hu , Xin Liu , Hairong Zheng , Leslie Ying , Dong Liang

Deep learning has achieved significant breakthroughs in medical imaging, but these advancements are often dependent on large, well-annotated datasets. However, obtaining such datasets poses a significant challenge, as it requires…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Siteng Ma , Honghui Du , Yu An , Jing Wang , Qinqin Wang , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Ruijie Zhang , Qiaozhe Zhang , Yingzhuang Liu , Hao Xin , Yan Liu , Xinggang Wang

Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hanene Ben Yedder , Ben Cardoen , Ghassan Hamarneh

Applying machine learning technologies, especially deep learning, into medical image segmentation is being widely studied because of its state-of-the-art performance and results. It can be a key step to provide a reliable basis for clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-03-08 Ziyang Wang

Introducing interpretability and reasoning into Multiple Instance Learning (MIL) methods for Whole Slide Image (WSI) analysis is challenging, given the complexity of gigapixel slides. Traditionally, MIL interpretability is limited to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Saarthak Kapse , Pushpak Pati , Srijan Das , Jingwei Zhang , Chao Chen , Maria Vakalopoulou , Joel Saltz , Dimitris Samaras , Rajarsi R. Gupta , Prateek Prasanna

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor problems for people with a detrimental effect on the functioning of the nervous system. In order to diagnose MS, multiple screening methods have been…

Deep Learning has shown great success in reshaping medical imaging, yet it faces numerous challenges hindering widespread application. Issues like catastrophic forgetting and distribution shifts in the continuously evolving data stream…

Computer Vision and Pattern Recognition · Computer Science 2024-10-02 Mohammad Areeb Qazi , Anees Ur Rehman Hashmi , Santosh Sanjeev , Ibrahim Almakky , Numan Saeed , Camila Gonzalez , Mohammad Yaqub

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

An increasing number of applications in computer vision, specially, in medical imaging and remote sensing, become challenging when the goal is to classify very large images with tiny informative objects. Specifically, these classification…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Fanjie Kong , Ricardo Henao