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We present a Machine Learning approach based on Symbolic Regression to derive, from either numerically generated or experimentally measured spectral data, closed-form expressions that model the optical properties of biological materials. To…

Computational Physics · Physics 2025-08-26 Julian Sierra-Velez , Alexandre Vial , Marina Inchaussandague , Diana Skigin , Demetrio Macías

Manipulation of the refractive index has been of growing interest lately. We consider parameters and possibilities of enhancing the absolute-value limit of the linear index in coherent atomic systems. Starting with a review of how two-level…

Optics · Physics 2024-02-20 Robert A. McCutcheon , Susanne F. Yelin

The detection of single particles or molecules represents a critical milestone in the development of biosensing technologies. Recently developed optical sensors based on quasi-bound states in the continuum (qBICs) have primarily focused on…

Current experimental and theoretical studies on the effect of intermolecular interactions on molecular conduction appear to be in conflict with each other. In particular, some experimental results, e.g., the observation of 2-dimensional…

Mesoscale and Nanoscale Physics · Physics 2007-07-23 A. Landau , L. Kronik , A. Nitzan

Increasing the refractive index available for optical and nanophotonic systems opens new vistas for design: for applications ranging from broadband metalenses to ultrathin photovoltaics to high-quality-factor resonators, higher index…

Optics · Physics 2021-03-30 Hyungki Shim , Francesco Monticone , Owen D. Miller

We present a quantitative finite temperature analysis of a recent experiment with Bose-Fermi mixtures in optical lattices, in which the dependence of the coherence of bosons on the inter-species interaction was analyzed. Our theory…

Quantum Gases · Physics 2013-05-29 M. Cramer

Optical systems capable of generating fields with sub-wavelength spatial features have become standard in science and engineering research and industry. Pertinent examples include atom- and ion-based quantum computers and optical…

Atomic Physics · Physics 2025-11-18 Nikhil Kotibhaskar , Sainath Motlakunta , Anthony Vogliano , Lewis Hahn , Rajibul Islam

Cells respond to chemical cues, and the precision with which they can sense these cues is fundamentally limited by the stochastic nature of diffusion and ligand binding. Berg and Purcell famously investigated how well a small sensor in an…

Biological Physics · Physics 2025-03-21 Daniel R. McCusker , David K. Lubensky

Optical binding interactions between laser-trapped spherical microparticles are familiar in a wide range of trapping configurations. Recently it has been demonstrated that these experiments can be accurately modeled using Mie scattering or…

Optics · Physics 2015-05-13 J. M. Taylor , G. D. Love

The scale free structure p(k)~k^{-gamma} of protein-protein interaction networks can be reproduced by a static physical model in simulation. We inspect the model theoretically, and find the key reason for the model to generate apparent…

Molecular Networks · Quantitative Biology 2015-06-26 Jingshan Zhang , Eugene I. Shakhnovich

We consider passive imaging tasks involving discrimination between known candidate objects and investigate the best possible accuracy with which the correct object can be identified. We analytically compute quantum-limited error bounds for…

Quantum Physics · Physics 2022-10-26 Michael R Grace , Saikat Guha

We characterize the interaction between a single atom or similar microscopic system and a light field via the scattering ratio. For that, we first derive the electrical field in a strongly focused Gaussian light beam, and then consider the…

We have implemented a multi-functional optofluidic sensor that can monitor changes in the refractive index and pressure of biofluid simultaneously and can detect free-solution molecular interaction in-situ. In this paper, we demonstrate two…

Optics · Physics 2014-10-16 Zhida Xu , Logan Liu

Existing elastic network models are typically parametrized at a given cutoff distance and often fail to properly predict the thermal fluctuation of many macromolecules that involve multiple characteristic length scales. We introduce a…

Biomolecules · Quantitative Biology 2015-05-21 Kristopher Opron , Kelin Xia , Guo-Wei Wei

The dispersive optical-model is applied to transfer reactions. A systematic study of $(d,p)$ reactions on closed-shell nuclei using the finite-range adiabatic reaction model is performed at several beam energies and results are compared to…

Nuclear Theory · Physics 2011-10-25 N. B. Nguyen , S. J. Waldecker , F. M. Nunes , R. J. Charity , W. H. Dickhoff

A novel method is proposed to measure the refractive indices (RIs) of the materials of different transparent solid state media. To exploit the advantage of non-contact measurement laser beam interferometry is used as an effective technique…

Physics Education · Physics 2024-06-19 Arnab Pal , Kriti R. Sahu , Pradipta Panchadhyayee , Debapriyo Syam

Interactions between surfaces and proteins occur in many vital processes and are crucial in biotechnology: the ability to control specific interactions is essential in fields like biomaterials, biomedical implants and biosensors. In the…

Computational Physics · Physics 2016-04-20 Christopher D. Cooper , Lorena A. Barba

Single-molecule detection enables direct observation of individual biomolecular events, providing mechanistic insights into biological processes and offering a powerful tool for disease diagnostics. However, the fundamental scale mismatch…

Optics · Physics 2025-10-14 Guifeng Li , Chaoyang Gong

Highly-resolved determination of refractive index is vital in fields ranging from biosensing through to laser range-finding. Laser speckle is known to be a sensitive probe of the properties of the light and the environment, but to date…

Optics · Physics 2021-09-07 Morgan Facchin , Graham David Bruce , Kishan Dholakia

The resolution of optical imaging devices is ultimately limited by the diffraction of light. To circumvent this limit, modern super-resolution microscopy techniques employ active interaction with the object by exploiting its optical…

Optics · Physics 2022-01-05 A. A. Pushkina , G. Maltese , J. I. Costa-Filho , P. Patel , A. I. Lvovsky