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Intelligent agents offer a new and exciting way of understanding the world of work. Agent-Based Simulation (ABS), one way of using intelligent agents, carries great potential for progressing our understanding of management practices and how…

Artificial Intelligence · Computer Science 2010-07-05 Peer-Olaf Siebers , Uwe Aickelin , Helen Celia , Chris Clegg

Agent-based modeling (ABM) is a well-established paradigm for simulating complex systems via interactions between constituent entities. Machine learning (ML) refers to approaches whereby statistical algorithms 'learn' from data on their…

Quantitative Methods · Quantitative Biology 2022-11-10 Nikita Sivakumar , Cameron Mura , Shayn M. Peirce

Through the collaboration of multiple LLM-empowered agents possessing diverse expertise and tools, multi-agent systems achieve impressive progress in solving real-world problems. Given the user queries, the meta-agents, serving as the brain…

Artificial Intelligence · Computer Science 2025-03-12 Ao Li , Yuexiang Xie , Songze Li , Fugee Tsung , Bolin Ding , Yaliang Li

Alzheimer's disease (AD) presents a complex, multifaceted challenge to patients, caregivers, and the healthcare system, necessitating integrated and dynamic support solutions. While artificial intelligence (AI) offers promising avenues for…

Multiagent Systems · Computer Science 2025-10-13 Adib Bazgir , Amir Habibdoust , Xing Song , Yuwen Zhang

Artificial Intelligence (AI) systems based solely on neural networks or symbolic computation present a representational complexity challenge. While minimal representations can produce behavioral outputs like locomotion or simple…

Neurons and Cognition · Quantitative Biology 2022-10-19 Bradly Alicea , Jesse Parent

The understanding of human central nervous system depends on knowledge of its wiring. However, there are still gaps in our understanding of its wiring due to technical difficulties. While some information is coming out from human…

Neural and Evolutionary Computing · Computer Science 2012-09-17 Önder Gürcan , Oğuz Dikenelli , Kemal S. Türker

Multiscale models provide a unique tool for studying complex processes that study events occurring at different scales across space and time. In the context of biological systems, such models can simulate mechanisms happening at the…

Quantitative Methods · Quantitative Biology 2024-06-27 Marco Ruscone , Andrea Checcoli , Randy Heiland , Emmanuel Barillot , Paul Macklin , Laurence Calzone , Vincent Noël

Agent-based modeling (ABM) is a powerful computational approach for studying complex biological and biomedical systems, yet its widespread use remains limited by significant computational demands. As models become increasingly…

Quantitative Methods · Quantitative Biology 2025-04-17 Kerri-Ann Norton , Daniel Bergman , Harsh Vardhan Jain , Trachette Jackson

Epidemiological models can not only be used to forecast the course of a pandemic like COVID-19, but also to propose and design non-pharmaceutical interventions such as school and work closing. In general, the design of optimal policies…

Optimization and Control · Mathematics 2023-04-06 Jan-Hendrik Niemann , Samuel Uram , Sarah Wolf , Nataša Djurdjevac Conrad , Martin Weiser

There is great potential to be explored regarding the use of agent-based modelling and simulation as an alternative paradigm to investigate early-stage cancer interactions with the immune system. It does not suffer from some limitations of…

Multiagent Systems · Computer Science 2015-06-22 Grazziela P Figueredo , Peer-Olaf Siebers , Markus R Owen , Jenna Reps , Uwe Aickelin

The study of system complexity primarily has two objectives: to explore underlying patterns and to develop theoretical explanations. Pattern exploration seeks to clarify the mechanisms behind the emergence of system complexity, while…

Multiagent Systems · Computer Science 2026-02-18 Xiao Xue , Deyu Zhou , Ming Zhang , Xiangning Yu , Fei-Yue Wang

Cellular Agent-Based Models are commonly employed to describe a variety biological systems. Over the course of the past years, many modeling tools have emerged which solve particular research questions. In this short opinion piece, we argue…

Cell Behavior · Quantitative Biology 2025-11-18 Jonas Pleyer

Formal modelling of Multi-Agent Systems (MAS) is a challenging task due to high complexity, interaction, parallelism and continuous change of roles and organisation between agents. In this paper we record our research experience on formal…

Multiagent Systems · Computer Science 2010-08-20 Petros Kefalas , Ioanna Stamatopoulou

It is essential to understand the complex structure of the human brain to develop new treatment approaches for neurodegenerative disorders (NDDs). This review paper comprehensively discusses the challenges associated with modelling the…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

Modelling and computational methods have been essential in advancing quantitative science, especially in the past two decades with the availability of vast amount of complex, voluminous, and heterogeneous data. In particular, there has been…

Multiagent Systems · Computer Science 2020-07-09 Affan Shoukat , Seyed M. Moghadas

The development of intelligent agents, particularly those powered by language models (LMs), has shown a critical role in various environments that require intelligent and autonomous decision-making. Environments are not passive testing…

Artificial Intelligence · Computer Science 2025-10-21 Antonin Sulc , Thorsten Hellert

A complex system is made up of many components with many interactions. So the design of systems such as simulation systems, cooperative systems or assistance systems includes a very accurate modelling of interactional and communicational…

Multiagent Systems · Computer Science 2012-01-19 Alain-Jérôme Fougères

Computer simulations offer a robust toolset for exploring complex systems across various disciplines. A particularly impactful approach within this realm is Agent-Based Modeling (ABM), which harnesses the interactions of individual agents…

Artificial Intelligence · Computer Science 2023-12-19 Zengqing Wu , Run Peng , Xu Han , Shuyuan Zheng , Yixin Zhang , Chuan Xiao

There has been a growing interest in enhancing rule-based agent-based models (ABMs) for social media platforms (i.e., X, Reddit) with more realistic large language model (LLM) agents, thereby allowing for a more nuanced study of complex…

Agent technology is a software paradigm that permits to implement large and complex distributed applications. In order to assist the development of multi-agent systems, agent-oriented methodologies (AOM) have been created in the last years…

Software Engineering · Computer Science 2014-03-13 Mohamed Garoui , Belhassen Mazigh , Béchir El Ayeb , Abderrafiaa Koukam
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