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The presence and density of specific types of immune cells are important to understand a patient's immune response to cancer. However, immunofluorescence staining required to identify T cell subtypes is expensive, time-consuming, and rarely…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Georg Wölflein , In Hwa Um , David J Harrison , Ognjen Arandjelović

Semi-supervised learning for medical image segmentation is an important area of research for alleviating the huge cost associated with the construction of reliable large-scale annotations in the medical domain. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Chae Eun Lee , Hyelim Park , Yeong-Gil Shin , Minyoung Chung

Infrared (IR) microscopes measure spectral information that quantifies molecular content to assign the identity of biomedical cells but lack the spatial quality of optical microscopy to appreciate morphologic features. Here, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2019-12-20 Kianoush Falahkheirkhah , Kevin Yeh , Shachi Mittal , Luke Pfister , Rohit Bhargava

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

Understanding the 3D world from 2D projected natural images is a fundamental challenge in computer vision and graphics. Recently, an unsupervised learning approach has garnered considerable attention owing to its advantages in data…

Computer Vision and Pattern Recognition · Computer Science 2021-06-25 Takuhiro Kaneko

This paper presents a novel unsupervised segmentation method for 3D medical images. Convolutional neural networks (CNNs) have brought significant advances in image segmentation. However, most of the recent methods rely on supervised…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

Computer-aided analysis of biological images typically requires extensive training on large-scale annotated datasets, which is not viable in many situations. In this paper we present GAN-DL, a Discriminator Learner based on the StyleGAN2…

Image and Video Processing · Electrical Eng. & Systems 2023-07-13 Alessio Mascolini , Dario Cardamone , Francesco Ponzio , Santa Di Cataldo , Elisa Ficarra

Despite the success of deep neural networks in chest X-ray (CXR) diagnosis, supervised learning only allows the prediction of disease classes that were seen during training. At inference, these networks cannot predict an unseen disease…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Nasir Hayat , Hazem Lashen , Farah E. Shamout

Cross-modal hashing aims to map heterogeneous multimedia data into a common Hamming space, which can realize fast and flexible retrieval across different modalities. Unsupervised cross-modal hashing is more flexible and applicable than…

Computer Vision and Pattern Recognition · Computer Science 2017-12-04 Jian Zhang , Yuxin Peng , Mingkuan Yuan

The availability of large-scale annotated image datasets and recent advances in supervised deep learning methods enable the end-to-end derivation of representative image features that can impact a variety of image analysis problems. Such…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Euijoon Ahn , Jinman Kim , Ashnil Kumar , Michael Fulham , Dagan Feng

Fully unsupervised 3D representation learning has gained attention owing to its advantages in data collection. A successful approach involves a viewpoint-aware approach that learns an image distribution based on generative models (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2022-06-14 Takuhiro Kaneko

The lack of large labeled medical imaging datasets, along with significant inter-individual variability compared to clinically established disease classes, poses significant challenges in exploiting medical imaging information in a…

Computer Vision and Pattern Recognition · Computer Science 2022-09-27 Matteo Ferrante , Tommaso Boccato , Simeon Spasov , Andrea Duggento , Nicola Toschi

The literature on adversarial attacks in computer vision typically focuses on pixel-level perturbations. These tend to be very difficult to interpret. Recent work that manipulates the latent representations of image generators to create…

Machine Learning · Computer Science 2023-09-12 Stephen Casper , Max Nadeau , Dylan Hadfield-Menell , Gabriel Kreiman

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

Current 3D semi-supervised segmentation methods face significant challenges such as limited consideration of contextual information and the inability to generate reliable pseudo-labels for effective unsupervised data use. To address these…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

The rapid adoption of transformer-based models in computational pathology has enabled prediction of molecular and clinical biomarkers from H&E whole-slide images, yet interpretability has not kept pace with model complexity. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marco Gustav , Fabian Wolf , Christina Glasner , Nic G. Reitsam , Stefan Schulz , Kira Aschenbroich , Bruno Märkl , Sebastian Foersch , Jakob Nikolas Kather

Trained using only image class label, deep weakly supervised methods allow image classification and ROI segmentation for interpretability. Despite their success on natural images, they face several challenges over histology data where ROI…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Is self-supervised deep learning (DL) for medical image analysis already a serious alternative to the de facto standard of end-to-end trained supervised DL? We tackle this question for medical image classification, with a particular focus…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Maximilian Nielsen , Laura Wenderoth , Thilo Sentker , René Werner

We propose a unified Generative Adversarial Network (GAN) for controllable image-to-image translation, i.e., transferring an image from a source to a target domain guided by controllable structures. In addition to conditioning on a…

Computer Vision and Pattern Recognition · Computer Science 2020-10-28 Hao Tang , Hong Liu , Nicu Sebe