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Investigating neural activity from a global brain perspective in-vivo has been in the domain of functional Magnetic Resonance Imaging (fMRI) over the past few decades. The intricate neurovascular couplings that govern fMRI's…

Medical Physics · Physics 2019-03-20 Daniel Nunes , Andrada Ianus , Noam Shemesh

Modern imaging techniques for probing brain function, including functional Magnetic Resonance Imaging, intrinsic and extrinsic contrast optical imaging, and magnetoencephalography, generate large data sets with complex content. In this…

Neurons and Cognition · Quantitative Biology 2009-11-10 P. P. Mitra , B. Pesaran

Functional MRI measuring BOLD signal is an increasingly important imaging modality in studying brain functions and neurological disorders. It can be acquired in either a resting-state or a task-based paradigm. Compared to resting-state…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Jiyao Wang , Nicha C. Dvornek , Peiyu Duan , Lawrence H. Staib , James S. Duncan

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

Machine Learning · Computer Science 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

Functional magnetic resonance imaging (fMRI) is an indispensable tool in modern neuroscience, providing a non-invasive window into whole-brain dynamics at millimeter-scale spatial resolution. However, fMRI is constrained by issues such as…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Yamin Li , Ange Lou , Ziyuan Xu , Shengchao Zhang , Shiyu Wang , Dario J. Englot , Soheil Kolouri , Daniel Moyer , Roza G. Bayrak , Catie Chang

Functional magnetic resonance imaging (fMRI) data provides information concerning activity in the brain and in particular the interactions between brain regions. Resting state fMRI data is widely used for inferring connectivities in the…

Applications · Statistics 2019-03-04 Christina Stoehr , John A D Aston , Claudia Kirch

In the last decade, fNIRS has provided a non-invasive method to investigate neural activation in developmental populations. Despite its increasing use in developmental cognitive neuroscience, there is little consistency or consensus on how…

Neurons and Cognition · Quantitative Biology 2022-11-29 Maria Laura Filippetti , Javier Andreu-Perez , Carina de Klerk , Chloe Richmond , Silvia Rigato

Malnutrition is a main public health problem in developing countries. Incidence is increasing and the mortality rate is still high. Malnutrition can leads mayor problems that can be irreversible if it is present before brain development is…

Neurons and Cognition · Quantitative Biology 2013-01-21 R. Martin , R. Godinez , A. O. Rodriguez

Background: Functional magnetic resonance imaging (fMRI) provides non-invasive measures of neuronal activity using an endogenous Blood Oxygenation-Level Dependent (BOLD) contrast. This article introduces a nonlinear dimensionality reduction…

Image and Video Processing · Electrical Eng. & Systems 2019-12-09 Gagan Sidhu

Functional Magnetic Resonance Imaging (fMRI) data is a widely used kind of four-dimensional biomedical data, which requires effective compression. However, fMRI compressing poses unique challenges due to its intricate temporal dynamics, low…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ruoran Li , Runzhao Yang , Wenxin Xiang , Yuxiao Cheng , Tingxiong Xiao , Jinli Suo

Cardiac magnetic resonance imaging (MRI) requires reconstructing a real-time video of a beating heart from continuous highly under-sampled measurements. This task is challenging since the object to be reconstructed (the heart) is…

Image and Video Processing · Electrical Eng. & Systems 2024-01-12 Johannes F. Kunz , Stefan Ruschke , Reinhard Heckel

Functional MRI (fMRI) has become the most common method for investigating the human brain. However, fMRI data present some complications for statistical analysis and modeling. One recently developed approach to these data focuses on…

Applications · Statistics 2015-03-19 Vincent Q. Vu , Pradeep Ravikumar , Thomas Naselaris , Kendrick N. Kay , Jack L. Gallant , Bin Yu

Functional brain imaging allows measuring dynamic functionality in all brain regions. It is broadly used in clinical cognitive neuroscience as, well as in research. It will allow the observation of neural activities in the brain…

Medical Physics · Physics 2016-04-01 Saman Sarraf , Jian Sun

The auditory pathway is widely distributed throughout the brain, and is perhaps one of the most interesting networks in the context of neuroplasticity. Accurate mapping of neural activity in the entire pathway, preferably noninvasively, and…

Medical Physics · Physics 2019-03-21 Guilherme Blazquez Freches , Cristina Chavarrias , Noam Shemesh

Functional magnetic resonance imaging (fMRI) is one of the most common imaging modalities to investigate brain functions. Recent studies in neuroscience stress the great potential of functional brain networks constructed from fMRI data for…

Machine Learning · Computer Science 2022-05-31 Xuan Kan , Hejie Cui , Joshua Lukemire , Ying Guo , Carl Yang

Brain activation mapping using functional MRI (fMRI) based on blood oxygenation level-dependent (BOLD) contrast has been conventionally focused on probing gray matter, the BOLD contrast in white matter having been generally disregarded.…

Signal Processing · Electrical Eng. & Systems 2019-10-25 David Abramian , Martin Larsson , Anders Eklund , Hamid Behjat

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

This technical note presents a framework for investigating the underlying mechanisms of neurovascular coupling in the human brain using multi-modal magnetoencephalography (MEG) and functional magnetic resonance (fMRI) neuroimaging data.…

Quantitative Methods · Quantitative Biology 2019-03-19 Amirhossein Jafarian , Vladimir Litvak , Hayriye Cagnan , Karl J. Friston , Peter Zeidman

Functional magnetic resonance imaging (fMRI) is now a well-established technique for studying the brain. However, in many situations, such as when data are acquired in a resting state, it is difficult to know whether the data are truly…

Applications · Statistics 2013-01-15 John A. D. Aston , Claudia Kirch

Voxel-based multiple testing is widely used in neuroimaging data analysis. Traditional false discovery rate (FDR) control methods often ignore the spatial dependence among the voxel-based tests and thus suffer from substantial loss of…

Machine Learning · Statistics 2024-05-06 Taehyo Kim , Hai Shu , Qiran Jia , Mony J. de Leon