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Ordinal outcomes are common in clinical settings where they often represent increasing levels of disease progression or different levels of functional impairment. Such outcomes can characterize differences in meaningful patient health…

We study time-inhomogeneous episodic reinforcement learning (RL) under general function approximation and sparse rewards. We design a new algorithm, Variance-weighted Optimistic $Q$-Learning (VO$Q$L), based on $Q$-learning and bound its…

Machine Learning · Computer Science 2022-12-13 Alekh Agarwal , Yujia Jin , Tong Zhang

Most Reinforcement Learning (RL) methods are traditionally studied in an active learning setting, where agents directly interact with their environments, observe action outcomes, and learn through trial and error. However, allowing…

Artificial Intelligence · Computer Science 2023-10-16 Maryam Zare , Parham M. Kebria , Abbas Khosravi

We propose Deep Optimistic Linear Support Learning (DOL) to solve high-dimensional multi-objective decision problems where the relative importances of the objectives are not known a priori. Using features from the high-dimensional inputs,…

Artificial Intelligence · Computer Science 2016-10-11 Hossam Mossalam , Yannis M. Assael , Diederik M. Roijers , Shimon Whiteson

It is a highly desirable property for deep networks to be robust against small input changes. One popular way to achieve this property is by designing networks with a small Lipschitz constant. In this work, we propose a new technique for…

Machine Learning · Computer Science 2023-09-04 Bernd Prach , Christoph H. Lampert

While Reinforcement Learning (RL) shows promise in training tool-use Large Language Models (LLMs) using verifiable outcome rewards, existing methods largely overlook the potential of reasoning rewards based on chain-of-thought quality for…

Computation and Language · Computer Science 2026-01-16 Zihan Lin , Xiaohan Wang , Hexiong Yang , Jiajun Chai , Jie Cao , Guojun Yin , Wei Lin , Ran He

Optimal treatment regime is the individualized treatment decision rule which yields the optimal treatment outcomes in expectation. A simple case of treatment decision rule is the linear decision rule, which is characterized by its…

Methodology · Statistics 2023-05-03 Angzhi Fan

Residual-based adaptive strategies are widely used in scientific machine learning but remain largely heuristic. We introduce a unifying variational framework that formalizes these methods by integrating convex transformations of the…

Machine Learning · Computer Science 2025-09-29 Juan Diego Toscano , Daniel T. Chen , Vivek Oommen , Jérôme Darbon , George Em Karniadakis

Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned…

Reinforcement learning (RL) has shown great success in estimating sequential treatment strategies which take into account patient heterogeneity. However, health-outcome information, which is used as the reward for reinforcement learning…

Machine Learning · Computer Science 2021-02-24 Aaron Sonabend-W , Nilanjana Laha , Ashwin N. Ananthakrishnan , Tianxi Cai , Rajarshi Mukherjee

We consider a natural semi-online model for weighted paging, where at any time the algorithm is given predictions, possibly with errors, about the next arrival of each page. The model is inspired by Belady's classic optimal offline…

Data Structures and Algorithms · Computer Science 2021-11-10 Nikhil Bansal , Christian Coester , Ravi Kumar , Manish Purohit , Erik Vee

With the advancement in drug development, multiple treatments are available for a single disease. Patients can often benefit from taking multiple treatments simultaneously. For example, patients in Clinical Practice Research Datalink (CPRD)…

Applications · Statistics 2018-04-17 Muxuan Liang , Ye Ting , Haoda Fu

We consider reinforcement learning (RL) methods in offline domains without additional online data collection, such as mobile health applications. Most of existing policy optimization algorithms in the computer science literature are…

Machine Learning · Statistics 2022-07-28 Chengchun Shi , Shikai Luo , Yuan Le , Hongtu Zhu , Rui Song

Active learning (AL) is a promising ML paradigm that has the potential to parse through large unlabeled data and help reduce annotation cost in domains where labeling data can be prohibitive. Recently proposed neural network based AL…

Machine Learning · Computer Science 2022-06-17 Prateek Munjal , Nasir Hayat , Munawar Hayat , Jamshid Sourati , Shadab Khan

Continual learning has emerged as a pivotal area of research, primarily due to its advantageous characteristic that allows models to persistently acquire and retain information. However, catastrophic forgetting can severely impair model…

Machine Learning · Computer Science 2026-01-28 KaiHui Huang , RunQing Wu , JinHui Sheng , HanYi Zhang , Ling Ge , JinYu Guo , Fei Ye

The rapid advancements in Large Language Models (LLMs) have revolutionized various natural language processing tasks. However, the substantial size of LLMs presents significant challenges in training or fine-tuning. While…

Machine Learning · Computer Science 2025-06-10 Pengxiang Li , Lu Yin , Xiaowei Gao , Shiwei Liu

This paper introduces the offline meta-reinforcement learning (offline meta-RL) problem setting and proposes an algorithm that performs well in this setting. Offline meta-RL is analogous to the widely successful supervised learning strategy…

Machine Learning · Computer Science 2021-07-22 Eric Mitchell , Rafael Rafailov , Xue Bin Peng , Sergey Levine , Chelsea Finn

First-order methods have been studied for nonlinear constrained optimization within the framework of the augmented Lagrangian method (ALM) or penalty method. We propose an improved inexact ALM (iALM) and conduct a unified analysis for…

Optimization and Control · Mathematics 2021-03-25 Zichong Li , Pin-Yu Chen , Sijia Liu , Songtao Lu , Yangyang Xu

The ordered weighted $\ell_1$ norm (OWL) was recently proposed, with two different motivations: its good statistical properties as a sparsity promoting regularizer; the fact that it generalizes the so-called {\it octagonal shrinkage and…

Data Structures and Algorithms · Computer Science 2015-04-13 Xiangrong Zeng , Mário A. T. Figueiredo

Weight play an essential role in deep learning network models. Unlike network structure design, this article proposes the concept of weight augmentation, focusing on weight exploration. The core of Weight Augmentation Strategy (WAS) is to…

Machine Learning · Computer Science 2024-05-31 Junbin Zhuang , Guiguang Din , Yunyi Yan