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RNA co-transcriptional folding has long been suspected to play an active role in helping proper native folding of ribozymes and structured regulatory motifs in mRNA untranslated regions. Yet, the underlying mechanisms and coding…

Biomolecules · Quantitative Biology 2007-05-23 A. Xayaphoummine , V. Viasnoff , S. Harlepp , H. Isambert

Sequence classification has numerous applications in various fields. Despite extensive studies in the last decades, many challenges still exist, particularly in pattern-based methods. Existing pattern-based methods measure the…

Machine Learning · Computer Science 2023-10-23 Junjie Dong , Mudi Jiang , Lianyu Hu , Zengyou He

Pairwise ordered tree alignment are combinatorial objects that appear in RNA secondary structure comparison. However, the usual representation of tree alignments as supertrees is ambiguous, i.e. two distinct supertrees may induce identical…

Quantitative Methods · Quantitative Biology 2016-03-08 Cedric Chauve , Julien Courtiel , Yann Ponty

We study plane trees as a model for RNA secondary structure, assigning energy to each tree based on the Nearest Neighbor Thermodynamic Model, and defining a corresponding Gibbs distribution on the trees. Through a bijection between plane…

Combinatorics · Mathematics 2020-04-03 Anna Kirkpatrick , Kalen Patton

In supervised learning using kernel methods, we often encounter a large-scale finite-sum minimization over a reproducing kernel Hilbert space (RKHS). Large-scale finite-sum problems can be solved using efficient variants of Newton method,…

Machine Learning · Computer Science 2022-06-07 Ting-Jui Chang , Shahin Shahrampour

In this paper, we aim to learn a mapping (or embedding) from images to a compact binary space in which Hamming distances correspond to a ranking measure for the image retrieval task. We make use of a triplet loss because this has been shown…

Computer Vision and Pattern Recognition · Computer Science 2016-08-02 Bohan Zhuang , Guosheng Lin , Chunhua Shen , Ian Reid

Sampling problems are promising candidates for demonstrating quantum advantage, and one approach known as quantum-enhanced Markov chain Monte Carlo [Layden, D. et al., Nature 619, 282-287 (2023)] uses quantum samples as a proposal…

Quantum Physics · Physics 2026-04-23 Yuya Kawamata , Yuichiro Nakano , Keisuke Fujii

We present several modifications to the previously proposed MSPP algorithm that can speed-up its execution considerably. The MSPP algorithm leverages a multiscale representation of the environment in $n$ dimensions. The information of the…

Data Structures and Algorithms · Computer Science 2016-02-16 Florian Hauer , Panagiotis Tsiotras

We propose a new deterministic methodology to predict RNA sequence and protein folding. Is stem enough for structure prediction? The main idea is to consider all possible stem formation in the given sequence. With the stem loop energy and…

Discrete Mathematics · Computer Science 2022-01-19 Mengyi Tang , Kumbit Hwang , Sung Ha Kang

In this paper, we propose a simple but effective method for fast image segmentation. We re-examine the locality-preserving character of spectral clustering by constructing a graph over image regions with both global and local connections.…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Zizhao Zhang , Fuyong Xing , Hanzi Wang , Yan Yan , Ying Huang , Xiaoshuang Shi , Lin Yang

As a report of a teaching experience, we analyse Haskell programs computing two integer sequences: the Hamming sequence and the Ulam sequence. For both of them, we investigate two strategies of computation: the first is based on filtering…

Programming Languages · Computer Science 2018-08-02 Ivano Salvo , Agnese Pacifico

This paper presents an efficient method to perform Structured Matrix Approximation by Separation and Hierarchy (SMASH), when the original dense matrix is associated with a kernel function. Given points in a domain, a tree structure is first…

Numerical Analysis · Mathematics 2017-05-17 Difeng Cai , Edmond Chow , Yousef Saad , Yuanzhe Xi

We present an efficient phylogenetic reconstruction algorithm allowing insertions and deletions which provably achieves a sequence-length requirement (or sample complexity) growing polynomially in the number of taxa. Our algorithm is…

Probability · Mathematics 2013-02-25 Constantinos Daskalakis , Sebastien Roch

A growing number of RNA sequences are now known to have distributions of multiple stable sequences. Recent algorithms use the list of nucleotides in a sequence and auxiliary experimental data to predict such distributions. Although the…

Combinatorics · Mathematics 2020-09-14 Torin Greenwood , Christine E. Heitsch

The matching distance is a computationally tractable topological measure to compare multi-filtered simplicial complexes. We design efficient algorithms for approximating the matching distance of two bi-filtered complexes to any desired…

Computational Geometry · Computer Science 2020-04-02 Michael Kerber , Arnur Nigmetov

DNA-based storage offers unprecedented density and durability, but its scalability is fundamentally limited by the efficiency of parallel strand synthesis. Existing methods either allow unconstrained nucleotide additions to individual…

Information Theory · Computer Science 2025-10-27 Boaz Moav , Ryan Gabrys , Eitan Yaakobi

Rate splitting multiple access (RSMA) relies on beamforming design for attaining spectral efficiency and energy efficiency gains over traditional multiple access schemes. While conventional optimization approaches such as weighted minimum…

Signal Processing · Electrical Eng. & Systems 2024-07-10 Yiwen Wang , Yijie Mao , Sijie Ji

Generating hyperspectral images (HSIs) from RGB images through spectral reconstruction can significantly reduce the cost of HSI acquisition. In this paper, we propose a Fractal-Based Recursive Spectral Reconstruction Network (FRN), which…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Ge Meng , Zhongnan Cai , Ruizhe Chen , Jingyan Tu , Yingying Wang , Yue Huang , Xinghao Ding

This paper aims to deliver an efficient and modified approach for image retrieval using multiple neural hash codes and limiting the number of queries using bloom filters by identifying false positives beforehand. Traditional approaches…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Sourin Chakrabarti

A graph homomorphism is a map between two graphs that preserves adjacency relations. We consider the problem of sampling a random graph homomorphism from a graph into a large network. We propose two complementary MCMC algorithms for…

Probability · Mathematics 2023-01-11 Hanbaek Lyu , Facundo Memoli , David Sivakoff