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While linear registration is a critical step in MRI preprocessing pipelines, its numerical uncertainty is understudied. Using Monte-Carlo Arithmetic (MCA) simulations, we assessed the most commonly used linear registration tools within…

Quantitative Methods · Quantitative Biology 2025-09-01 Niusha Mirhakimi , Yohan Chatelain , Tristan Glatard , Jean-Baptiste Poline

The standard approach to the analysis of functional magnetic resonance imaging (FMRI) data applies various preprocessing steps to the original FMRI. These preprocessings lead to a general underestimation of residual variance in the…

Applications · Statistics 2018-09-20 Thomas Wilhelm Dieter Möbius

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise…

Statistics Theory · Mathematics 2015-10-30 Ching-Shui Cheng , Ming-Hung Kao

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

A statistical approach for combination of channel phases is developed for optimizing the Contrast-to-Noise Ratio (CNR) in Susceptibility Weighted Images (SWI) acquired using autocalibrating partially parallel techniques. The unwrapped phase…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Sreekanth Madhusoodhanan , Joseph Suresh Paul

Fetal functional Magnetic Resonance Imaging (fMRI) has emerged as a powerful tool for investigating brain development in utero, holding promise for generating developmental disease biomarkers and supporting prenatal diagnosis. However, to…

Magnetic resonance imaging (MRI) is widely used for screening, diagnosis, image-guided therapy, and scientific research. A significant advantage of MRI over other imaging modalities such as computed tomography (CT) and nuclear imaging is…

Image and Video Processing · Electrical Eng. & Systems 2020-02-20 Qing Lyu , Hongming Shan , Ge Wang

Early detection is crucial for timely intervention aimed at preventing and slowing the progression of neurocognitive disorder (NCD), a common and significant health problem among the aging population. Recent evidence has suggested that…

Computation and Language · Computer Science 2025-06-11 Yuejiao Wang , Xianmin Gong , Xixin Wu , Patrick Wong , Hoi-lam Helene Fung , Man Wai Mak , Helen Meng

Magnetic Resonance Imaging (MRI) is the primary imaging modality used in the diagnosis, assessment, and treatment planning for brain pathologies. However, most automated MRI analysis tools, such as segmentation and registration pipelines,…

Hyperspectral Imaging (HSI) for fluorescence-guided brain tumor resection enables visualization of differences between tissues that are not distinguishable to humans. This augmentation can maximize brain tumor resection, improving patient…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 David Black , Jaidev Gill , Andrew Xie , Benoit Liquet , Antonio Di leva , Walter Stummer , Eric Suero Molina

In this work we introduce a self-supervised pretraining framework for transformers on functional Magnetic Resonance Imaging (fMRI) data. First, we pretrain our architecture on two self-supervised tasks simultaneously to teach the model a…

Machine Learning · Computer Science 2023-05-17 Sean Paulsen , Michael Casey

We are glad that our paper has generated intense discussions in the fMRI field, on how to analyze fMRI data and how to correct for multiple comparisons. The goal of the paper was not to disparage any specific fMRI software, but to point out…

Applications · Statistics 2017-05-31 Anders Eklund , Thomas Nichols , Hans Knutsson

Resting State Networks (RSNs) of the brain extracted from Resting State functional Magnetic Resonance Imaging (RS-fMRI) are used in the pre-surgical planning to guide the neurosurgeon. This is difficult, though, as expert knowledge is…

Driven by the latest trend towards self-supervised learning (SSL), the paradigm of "pretraining-then-finetuning" has been extensively explored to enhance the performance of clinical applications with limited annotations. Previous literature…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Chuyan Zhang , Yuncheng Yang , Hao Zheng , Yun Gu

Deep learning models are trained to minimize the error between the model's output and the actual values. The typical cost function, the Mean Squared Error (MSE), arises from maximizing the log-likelihood of additive independent, identically…

Machine Learning · Computer Science 2021-05-12 Anand Ramakrishnan , Warren B. Jackson , Kent Evans

Due to the imbalanced and limited data, semi-supervised medical image segmentation methods often fail to produce superior performance for some specific tailed classes. Inadequate training for those particular classes could introduce more…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 Hritam Basak , Sagnik Ghosal , Ram Sarkar

Functional Magnetic Resonance Images acquired during resting-state provide information about the functional organization of the brain through measuring correlations between brain areas. Independent components analysis is the reference…

Neurons and Cognition · Quantitative Biology 2014-12-15 Alexandre Abraham , Elvis Dohmatob , Bertrand Thirion , Dimitris Samaras , Gael Varoquaux

Materials and methods: First, a dual-time approach was assessed, for which the CNN was provided sequences of the MRI that initially depicted new MM (diagnosis MRI) as well as of a prediagnosis MRI: inclusion of only contrast-enhanced…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Katerina Deike-Hofmann , Dorottya Dancs , Daniel Paech , Heinz-Peter Schlemmer , Klaus Maier-Hein , Philipp Bäumer , Alexander Radbruch , Michael Götz

The technology of functional Magnetic Resonance Imaging (fMRI) based on Blood Oxygen Level Dependent (BOLD) signal has been widely used in clinical treatments and brain function researches. The BOLD signal has to be preprocessed before…

Neurons and Cognition · Quantitative Biology 2017-12-29 Yunxiang Ge , Yu Pan , Weibei Dou

This work introduces a novel approach to fMRI-based visual image reconstruction using a subject-agnostic common representation space. We show that the brain signals of the subjects can be aligned in this common space during training to form…

Image and Video Processing · Electrical Eng. & Systems 2025-10-10 Christos Zangos , Danish Ebadulla , Thomas Christopher Sprague , Ambuj Singh