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We show that for certain configurations of two chemostats fed in parallel, the presence of two different species in each tank can improve the yield of the whole process, compared to the same configuration having the same species in each…

Optimization and Control · Mathematics 2012-09-03 Denis Dochain , Patrick De Leenheer , Alain Rapaport

Given hydric capacity and nutrient flow of a chemostat-like system, we analyse the influence of a spatial structure on the output concentrations at steady-state. Three configurations are compared: perfectly-mixed, serial and parallel with…

Dynamical Systems · Mathematics 2010-11-17 Alain Rapaport , Ihab Haidar

In this work, we study a model of the chemostat where the species are present in two forms, isolated bacteria and under an aggregated form like attached bacteria or bacteria in flocks. We show that our general model contains a lot of models…

Dynamical Systems · Mathematics 2012-03-13 Radhoaune Fekih-Salem , Jérôme Harmand , Claude Lobry , Alain Rapaport , Tewfik Sari

We consider the modeling of the dynamics of the chemostat at its very source. The chemostat is classically represented as a system of ordinary differential equations. Our goal is to establish a stochastic model that is valid at the scale…

Quantitative Methods · Quantitative Biology 2011-07-07 Fabien Campillo , Marc Joannides , Irène Larramendy

The recently established connection between stochastic thermodynamics and fluctuating hydrodynamics is applied to a study of efficiencies in the coupled transport of heat and matter on a small scale. A stochastic model for a mesoscopic cell…

Statistical Mechanics · Physics 2019-04-01 Jean-François Derivaux , Yannick De Decker

We study the existence and uniqueness of the solution of a non-linear coupled system constituted of a degenerate diffusion-growth-fragmentation equation and a differential equation, resulting from the modeling of bacterial growth in a…

Analysis of PDEs · Mathematics 2023-03-22 Josué Tchouanti

We propose a simple quantum mechanical model describing the time dependent diffusion current between two fermion reservoirs that were initially disconnected and characterized by different densities or chemical potentials. The exact,…

Statistical Mechanics · Physics 2012-12-07 Wim Magnus , Kwinten Nelissen

We revisit the well-known chemostat model, considering that bacteria can be attached together in aggregates or flocs. We distinguish explicitly free and attached compartments in the model and give sufficient conditions for coexistence of…

Dynamical Systems · Mathematics 2018-03-08 Alain Rapaport

A chemostat enables long-term, continuous, exponential-phase growth in an environment limited as prescribed by the researcher. It is thus a potent tool for laboratory evolution - selecting for strains with desired phenotypes. However,…

Populations and Evolution · Quantitative Biology 2018-06-04 Aryeh Wides , Ron Milo

In this paper, we derive a new chemotaxis model with degenerate diffusion and density-dependent chemotactic sensitivity, and we provide a more realistic description of cell migration process for its early and late stages. Different from the…

Analysis of PDEs · Mathematics 2023-07-19 Tianyuan Xu , Shanming Ji , Chunhua Jin , Ming Mei , Jingxue Yin

The Crump-Young model consists of two fully coupled stochastic processes modeling the substrate and microorganisms dynamics in a chemostat. Substrate evolves following an ordinary differential equation whose coefficients depend of…

Probability · Mathematics 2022-05-12 Bertrand Cloez , Coralie Fritsch

We propose a model of chemostat where the bacterial population is individually-based, each bacterium is explicitly represented and has a mass evolving continuously over time. The substrate concentration is represented as a conventional…

Probability · Mathematics 2013-11-08 Fabien Campillo , Coralie Fritsch

In this paper, we study an optimal control problem for a coupled non-linear system of reaction-diffusion equations with degenerate diffusion, consisting of two partial differential equations representing the density of cells and the…

Optimization and Control · Mathematics 2024-07-11 Georges Chamoun , Mazen Saad , Toni Sayah , Sarah Serhal

Many processes in biology involve both reactions and chemotaxis. However, to the best of our knowledge, the question of interaction between chemotaxis and reactions has not yet been addressed either analytically or numerically. We consider…

Analysis of PDEs · Mathematics 2011-04-05 Alexander Kiselev , Lenya Ryzhik

We study the chemostat model for one species competing for one nutrient using a Lyapunov-type analysis. We design the dilution rate function so that all solutions of the chemostat converge to a prescribed periodic solution. In terms of…

Optimization and Control · Mathematics 2007-05-23 Frederic Mazenc , Michael Malisoff , Patrick De Leenheer

We explore how the interplay of finite availability, carrying capacity of particles at different parts of a spatially extended system and particle diffusion between them control the steady state currents and density profiles in a…

Statistical Mechanics · Physics 2024-12-04 Sourav Pal , Parna Roy , Abhik Basu

In this paper, we consider a flocculation model in a chemostat where one species is present in two forms: planktonic and aggregated bacteria with the presence of a single resource. The removal rates of isolated and attached bacteria are…

Dynamical Systems · Mathematics 2023-12-08 Radhouane Fekih-Salem , Tewfik Sari

In many real life applications, a continuous culture bioreactor may cease to function properly due to bioclogging which is typically caused by the microbial overgrowth. This is a problem that has been largely overlooked in the chemostat…

Populations and Evolution · Quantitative Biology 2024-11-11 Xiaochen Duan , Sergei S. Pilyugin

Lately, experimental research on microbial symbioses based on nutrient exchange and interdependence has yielded a number of interesting findings, however an in-depth mathematical description of the exact underlying dynamics of such…

Populations and Evolution · Quantitative Biology 2019-08-08 Matthias M. Fischer

Consider a particle diffusing in a confined volume which is divided into two equal regions. In one region the diffusion coefficient is twice the value of the diffusion coefficient in the other region. Will the particle spend equal…

Dynamical Systems · Mathematics 2015-06-04 P. F. Tupper , Xin Yang
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