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This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state…

Artificial Intelligence · Computer Science 2018-01-30 Ning Liu , Ying Liu , Brent Logan , Zhiyuan Xu , Jian Tang , Yanzhi Wang

We present a deep learning-based approach to studying dynamic clinical behavioral regimes in diverse non-randomized healthcare settings. Our proposed methodology - deep causal behavioral policy learning (DC-BPL) - uses deep learning…

Machine Learning · Statistics 2025-03-06 Jonas Knecht , Anna Zink , Jonathan Kolstad , Maya Petersen

Epilepsy is common neurological diseases, affecting about 0.6-0.8 % of world population. Epileptic patients suffer from chronic unprovoked seizures, which can result in broad spectrum of debilitating medical and social consequences. Since…

Quantitative Methods · Quantitative Biology 2017-06-13 Sachin S. Talathi

Epidemic decision-making can effectively help the government to comprehensively consider public security and economic development to respond to public health and safety emergencies. Epidemic decision-making can effectively help the…

Machine Learning · Computer Science 2023-11-06 Yangxi Zhou , Junping Du , Zhe Xue , Zhenhui Pan , Weikang Chen

We consider the problem of predicting how the likelihood of an outcome of interest for a patient changes over time as we observe more of the patient data. To solve this problem, we propose a supervised contrastive learning framework that…

Machine Learning · Computer Science 2024-04-16 Shahriar Noroozizadeh , Jeremy C. Weiss , George H. Chen

Systems and machines undergo various failure modes that result in machine health degradation, so maintenance actions are required to restore them back to a state where they can perform their expected functions. Since maintenance tasks are…

Machine Learning · Computer Science 2023-07-11 Oluwaseyi Ogunfowora , Homayoun Najjaran

Counterfactual prediction is about predicting outcome of the unobserved situation from the data. For example, given patient is on drug A, what would be the outcome if she switch to drug B. Most of existing works focus on modeling…

Machine Learning · Computer Science 2020-10-29 Yanbo Xu , Cao Xiao , Jimeng Sun

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Naloxone, an opioid antagonist, has been widely used to save lives from opioid overdose, a leading cause for death in the opioid epidemic. However, naloxone has short brain retention ability, which limits its therapeutic efficacy.…

Biomolecules · Quantitative Biology 2020-04-13 Jianyuan Deng , Zhibo Yang , Yao Li , Dimitris Samaras , Fusheng Wang

We introduce a Reinforcement Learning Psychotherapy AI Companion that generates topic recommendations for therapists based on patient responses. The system uses Deep Reinforcement Learning (DRL) to generate multi-objective policies for four…

Machine Learning · Computer Science 2023-03-20 Baihan Lin , Guillermo Cecchi , Djallel Bouneffouf

Pressure ulcers are a challenge for patients and healthcare professionals. In the UK, 700,000 people are affected by pressure ulcers each year. Treating them costs the National Health Service {\pounds}3.8 million every day. Their etiology…

Machine Learning · Computer Science 2022-03-15 Paul Fergus , Carl Chalmers , William Henderson , Danny Roberts , Atif Waraich

Learning-based approaches for solving large sequential decision making problems have become popular in recent years. The resulting agents perform differently and their characteristics depend on those of the underlying learning approach.…

Machine Learning · Computer Science 2020-08-04 Timo P. Gros , Daniel Höller , Jörg Hoffmann , Verena Wolf

Robotic catheterization is typically used for percutaneous coronary intervention procedures nowadays and it involves steering flexible endovascular tools to open up occlusion in the coronaries. In this study, a sample-efficient deep…

Robotics · Computer Science 2021-10-29 Olatunji Mumini Omisore , Toluwanimi Akinyemi , Wenke Duan , Wenjing Du , Lei Wang

Health-related data is noisy and stochastic in implying the true physiological states of patients, limiting information contained in single-moment observations for sequential clinical decision making. We model patient-clinician interactions…

Artificial Intelligence · Computer Science 2019-05-21 Luchen Li , Matthieu Komorowski , Aldo A. Faisal

Medical Triage is of paramount importance to healthcare systems, allowing for the correct orientation of patients and allocation of the necessary resources to treat them adequately. While reliable decision-tree methods exist to triage…

Decision makers, such as doctors and judges, make crucial decisions such as recommending treatments to patients, and granting bails to defendants on a daily basis. Such decisions typically involve weighting the potential benefits of taking…

Artificial Intelligence · Computer Science 2016-10-25 Himabindu Lakkaraju , Cynthia Rudin

Medical automatic diagnosis aims to imitate human doctors in real-world diagnostic processes and to achieve accurate diagnoses by interacting with the patients. The task is formulated as a sequential decision-making problem with a series of…

Machine Learning · Computer Science 2022-06-07 Hongyi Yuan , Sheng Yu

Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from…

Machine Learning · Computer Science 2024-04-10 Lillian Muyama , Antoine Neuraz , Adrien Coulet

In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a…

Machine Learning · Computer Science 2019-01-15 Ziyuan Pan , Hao Du , Kee Yuan Ngiam , Fei Wang , Ping Shum , Mengling Feng

This paper studies policy learning for continuous treatments from observational data. Continuous treatments present more significant challenges than discrete ones because population welfare may need nonparametric estimation, and policy…

Econometrics · Economics 2025-12-02 Chunrong Ai , Yue Fang , Haitian Xie