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We consider Pareto surface based multi-criteria optimization for step and shoot IMRT planning. By analyzing two navigation algorithms, we show both theoretically and in practice that the number of plans needed to form convex combinations of…

Medical Physics · Physics 2015-06-11 David Craft , Christian Richter

The evolution of gene regulatory networks in variable environments poses Multi-objective Optimization Problem (MOP), where the expression levels of genes must be tuned to meet the demands of each environment. When formalized in the context…

Optimization and Control · Mathematics 2018-04-23 Philippe Nghe , Bela M. Mulder , Sander J. Tans

Many existing branch and bound algorithms for multiobjective optimization problems require a significant computational cost to approximate the entire Pareto optimal solution set. In this paper, we propose a new branch and bound algorithm…

Optimization and Control · Mathematics 2024-05-20 Weitian Wu , Xinmin Yang

We present novel mathematical models for inventory management within a reverse logistics system. Technological advancements, sustainability initiatives, and evolving customer behaviours have significantly increased the demand for repaired…

Optimization and Control · Mathematics 2024-06-21 I. B. Wadhawan , M. M. Rizvi

This paper is concerned with a recently developed paradigm for population-based optimization, termed particle filter optimization (PFO). This paradigm is attractive in terms of coherence in theory and easiness in mathematical analysis and…

Machine Learning · Statistics 2018-11-26 Bin Liu , Yaochu Jin

Various local search approaches have recently been applied to machine scheduling problems under multiple objectives. Their foremost consideration is the identification of the set of Pareto optimal alternatives. An important aspect of…

Artificial Intelligence · Computer Science 2008-09-02 Martin Josef Geiger

Many machine learning tasks aim to find models that work well not for a single, but for a group of criteria, often opposing ones. One such example is imbalanced data classification, where, on the one hand, we want to achieve the best…

Machine Learning · Computer Science 2025-11-18 Szymon Wojciechowski , Michał Woźniak

Most performance measures of pilot-assisted multiple-input multiple-output (MIMO) systems are functions that depend on both the linear precoding filter and the pilot sequence. A framework for the optimization of these two parameters is…

Information Theory · Computer Science 2016-11-15 Adriano Pastore , Michael Joham , Javier Rodríguez Fonollosa

Multi-objective optimization (MOO) problems require balancing competing objectives, often under constraints. The Pareto optimal solution set defines all possible optimal trade-offs over such objectives. In this work, we present a novel…

Machine Learning · Computer Science 2022-04-19 Soumyajit Gupta , Gurpreet Singh , Raghu Bollapragada , Matthew Lease

We present a novel characterization of the mapping of multiple parallelism forms (e.g. data and model parallelism) onto hierarchical accelerator systems that is hierarchy-aware and greatly reduces the space of software-to-hardware mapping.…

Programming Languages · Computer Science 2021-11-17 Ningning Xie , Tamara Norman , Dominik Grewe , Dimitrios Vytiniotis

A genetic algorithm is suitable for exploring large search spaces as it finds an approximate solution. Because of this advantage, genetic algorithm is effective in exploring vast and unknown space such as molecular search space. Though the…

Neural and Evolutionary Computing · Computer Science 2021-12-24 Yurim Lee , Gydam Choi , Minsung Yoon , Cheongwon Kim

We propose a novel numerical approach to compute the Pareto front in multivariate polynomial multi-objective optimization problems. When the objective functions and (equality) constraints are multivariate polynomials, the Pareto front,…

Optimization and Control · Mathematics 2026-04-06 Hans van Rooij , Christof Vermeersch , Marie Deferme , Bart De Moor

We study the trade-offs between strategyproofness and other desiderata, such as efficiency or fairness, that often arise in the design of random ordinal mechanisms. We use approximate strategyproofness to define manipulability, a measure to…

Computer Science and Game Theory · Computer Science 2017-01-11 Timo Mennle , Sven Seuken

This paper introduces the first objective space algorithm which can exactly find all supported and non-supported non-dominated solutions to a mixed-integer multi-objective linear program with an arbitrary number of objective functions. This…

Optimization and Control · Mathematics 2019-09-10 William Pettersson , Melih Ozlen

Under the condition of Karush-Kuhn-Tucker, the Pareto Set (PS) in the decision area of an m-objective optimization problem is a piecewise continuous (m-1)-D manifold. For illustrate the degree of convergence of the population, we employed…

Neural and Evolutionary Computing · Computer Science 2019-11-27 Abel Sa J. R Malano , Guanjun Du , Guoxiang Tong , Naixue Xiong

In today's global business market place, individual firms no longer compete as independent entities with unique brand names but as integral part of supply chain links. Key to success of any business is satisfying customer's demands on time…

Optimization and Control · Mathematics 2014-08-05 Nelson Christopher Dzupire , Yaw Nkansah-Gyekye

The performance of multi-objective evolutionary algorithms deteriorates appreciably in solving many-objective optimization problems which encompass more than three objectives. One of the known rationales is the loss of selection pressure…

Neural and Evolutionary Computing · Computer Science 2018-02-27 Yanan Sun , Gary G. Yen , Zhang Yi

De novo molecular design has extensive applications in drug discovery and materials science. The vast chemical space renders direct molecular searches computationally prohibitive, while traditional experimental screening is both time- and…

Machine Learning · Computer Science 2025-04-03 Junyu Hou

This paper deals with shape irregularity issues in discrete topology optimization algorithms whereby the design is created using the automated distribution of material in the design region. Graph theory is employed to derive appropriate…

Information Theory · Computer Science 2025-03-14 Vojtech Neuman , Miloslav Capek , Lukas Jelinek

Retrosynthesis is the task of planning a series of chemical reactions to create a desired molecule from simpler, buyable molecules. While previous works have proposed algorithms to find optimal solutions for a range of metrics (e.g.…

Artificial Intelligence · Computer Science 2024-04-16 Austin Tripp , Krzysztof Maziarz , Sarah Lewis , Marwin Segler , José Miguel Hernández-Lobato
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