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Intratumor heterogeneity is often manifested by vascular compartments with distinct pharmacokinetics that cannot be resolved directly by in vivo dynamic imaging. We developed tissue-specific compartment modeling (TSCM), an unsupervised…

Quantitative Methods · Quantitative Biology 2017-02-08 Li Chen , Peter L. Choyke , Niya Wang , Robert Clarke , Zaver M. Bhujwalla , Elizabeth M. C. Hillman , Yue Wang

Deep learning algorithms have accounted for the rapid acceleration of research in artificial intelligence in medical image analysis, interpretation, and segmentation with many potential applications across various sub disciplines in…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Shanaka Ramesh Gunasekara , HNTK Kaldera , Maheshi B. Dissanayake

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Purpose: To develop an algorithm for real-time volumetric image reconstruction and 3D tumor localization based on a single x-ray projection image for lung cancer radiotherapy. Methods: Given a set of volumetric images of a patient at N…

Medical Physics · Physics 2015-05-18 Ruijiang Li , Xun Jia , John H. Lewis , Xuejun Gu , Michael Folkerts , Chunhua Men , Steve B. Jiang

Transrectal biopsies under 2D ultrasound (US) control are the current clinical standard for prostate cancer diagnosis. The isoechogenic nature of prostate carcinoma makes it necessary to sample the gland systematically, resulting in a low…

Computer Vision and Pattern Recognition · Computer Science 2011-07-11 Michael Baumann , Pierre Mozer , Vincent Daanen , Jocelyne Troccaz

Intraoperative ultrasound imaging is used to facilitate safe brain tumour resection. However, due to challenges with image interpretation and the physical scanning, this tool has yet to achieve widespread adoption in neurosurgery. In this…

Preoperative gestures include tactile sampling of the mechanical properties of biological tissue for both histological and pathological considerations. Tactile properties used in conjunction with visual cues can provide useful feedback to…

Graphics · Computer Science 2019-03-12 Felix G. Hamza-Lup , Adrian Seitan , Dorin M. Popovici , Crenguta M. Bogdan

In-vivo tissue stiffness identification can be useful in pulmonary fibrosis diagnostics and minimally invasive tumor identification, among many other applications. In this work, we propose a palpation-based method for tissue stiffness…

Minimally invasive surgery is highly operator dependant with a lengthy procedural time causing fatigue to surgeon and risks to patients such as injury to organs, infection, bleeding, and complications of anesthesia. To mitigate such risks,…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Mansoor Ali , Rafael Martinez Garcia Pena , Gilberto Ochoa Ruiz , Sharib Ali

Spatially aligning medical images from different modalities remains a challenging task, especially for intraoperative applications that require fast and robust algorithms. We propose a weakly-supervised, label-driven formulation for…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Yipeng Hu , Marc Modat , Eli Gibson , Nooshin Ghavami , Ester Bonmati , Caroline M. Moore , Mark Emberton , J. Alison Noble , Dean C. Barratt , Tom Vercauteren

The task of radiology reporting comprises describing and interpreting the medical findings in radiographic images, including description of their location and appearance. Automated approaches to radiology reporting require the image to be…

Computer Vision and Pattern Recognition · Computer Science 2023-08-31 Francesco Dalla Serra , Chaoyang Wang , Fani Deligianni , Jeffrey Dalton , Alison Q. O'Neil

Quantitative information on tumor heterogeneity and cell load could assist in designing effective and refined personalized treatment strategies. It was recently shown by us that such information can be inferred from the diffusion parameter…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Yi Yin , Kai Breuhahn , Hans-Ulrich Kauczor , Oliver Sedlaczek , Irene E. Vignon-Clementel , Dirk Drasdo

Dynamic volumetric MRI provides valuable information on in vivo motion and biomechanics, with applications spanning cardiac, musculoskeletal, or pulmonary imaging, amongst others. Developing reconstruction methods for time-resolved…

Deep neural networks are increasingly used for pair-wise image registration. We propose to extend current learning-based image registration to allow simultaneous registration of multiple images. To achieve this, we build upon the pair-wise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Tycho F. A. van der Ouderaa , Ivana Išgum , Wouter B. Veldhuis , Bob D. de Vos

Quantitative cancer image analysis relies on the accurate delineation of tumours, a very specialised and time-consuming task. For this reason, methods for automated segmentation of tumours in medical imaging have been extensively developed…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Saúl Alonso-Monsalve , Leigh H. Whitehead , Adam Aurisano , Lorena Escudero Sanchez

In this paper, an innovative microwave imaging (MI) approach for breast tumor diagnosis is proposed that employs a differential formulation of the inverse scattering problem (ISP) at hand to exploit arbitrary-fidelity priors on the…

Signal Processing · Electrical Eng. & Systems 2024-01-08 Francesco Zardi , Luca Tosi , Marco Salucci , Andrea Massa

Many tasks in robot-assisted surgeries (RAS) can be represented by finite-state machines (FSMs), where each state represents either an action (such as picking up a needle) or an observation (such as bleeding). A crucial step towards the…

Computer Vision and Pattern Recognition · Computer Science 2020-02-10 Yidan Qin , Sahba Aghajani Pedram , Seyedshams Feyzabadi , Max Allan , A. Jonathan McLeod , Joel W. Burdick , Mahdi Azizian

Robotic skill learning has been increasingly studied but the demonstration collections are more challenging compared to collecting images/videos in computer vision and texts in natural language processing. This paper presents a skill…

Robotics · Computer Science 2023-11-14 Xiangyu Chu , Yunxi Tang , Lam Him Kwok , Yuanpei Cai , Kwok Wai Samuel Au

Deep intracranial tumors situated in eloquent brain regions controlling vital functions present critical diagnostic challenges. Clinical practice has shifted toward stereotactic biopsy for pathological confirmation before treatment. Yet…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Xinzhe Luo , Shuai Shao , Yan Wang , Jiangtao Wang , Yutong Bai , Jianguo Zhang

Segmentation of surgical instruments is an important problem in robot-assisted surgery: it is a crucial step towards full instrument pose estimation and is directly used for masking of augmented reality overlays during surgical procedures.…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Daniil Pakhomov , Nassir Navab