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Motivation: Receptor-binding proteins (RBPs) initiate viral infection and determine host specificity, serving as key targets for phage engineering and therapy. However, the identification of RBPs is complicated by their extreme sequence…

Genomics · Quantitative Biology 2026-03-17 Xiling Luo , Le Ou-Yang , Yang Shen , Jiaojiao Guan , Dehan Cai , Jun Zhang , Yanni Sun , Jiayu Shang

Multi-view multi-label data offers richer perspectives for artificial intelligence, but simultaneously presents significant challenges for feature selection due to the inherent complexity of interrelations among features, views and labels.…

Machine Learning · Computer Science 2025-11-18 Yuzhou Liu , Jiarui Liu , Wanfu Gao

Feature selection eliminates redundancy among features to improve downstream task performance while reducing computational overhead. Existing methods often struggle to capture intricate feature interactions and adapt across diverse…

Machine Learning · Computer Science 2026-03-02 Rui Liu , Tao Zhe , Yanjie Fu , Feng Xia , Ted Senator , Dongjie Wang

Statistical boosting algorithms have triggered a lot of research during the last decade. They combine a powerful machine-learning approach with classical statistical modelling, offering various practical advantages like automated variable…

Feature selection is a crucial step in large-scale industrial machine learning systems, directly affecting model accuracy, efficiency, and maintainability. Traditional feature selection methods rely on labeled data and statistical…

Statistical methods for analyzing large-scale biomolecular data are commonplace in computational biology. A notable example is phenotype prediction from gene expression data, for instance, detecting human cancers, differentiating subtypes…

Genomics · Quantitative Biology 2014-11-24 Bahman Afsari , Ulisses M. Braga-Neto , Donald Geman

Discovery of diagnostic and prognostic molecular markers is important and actively pursued the research field in cancer research. For complex diseases, this process is often performed using Machine Learning. The current study compares two…

Genomics · Quantitative Biology 2020-04-30 Aneta Polewko-Klim , Witold R. Rudnicki

By Emerging huge databases and the need to efficient learning algorithms on these datasets, new problems have appeared and some methods have been proposed to solve these problems by selecting efficient features. Feature selection is a…

Computer Vision and Pattern Recognition · Computer Science 2016-01-21 Mitra Montazeri , Mahdieh Soleymani Baghshah , Aliakbar Niknafs

The effectiveness of machine learning models is significantly affected by the size of the dataset and the quality of features as redundant and irrelevant features can radically degrade the performance. This paper proposes IGRF-RFE: a hybrid…

Machine Learning · Computer Science 2023-02-07 Yuhua Yin , Julian Jang-Jaccard , Wen Xu , Amardeep Singh , Jinting Zhu , Fariza Sabrina , Jin Kwak

Retrieval-augmented generation (RAG) enhances large language models (LLMs) by integrating external knowledge retrieved from a knowledge base. However, its effectiveness is fundamentally constrained by the reliability of both the retriever…

Computation and Language · Computer Science 2025-01-31 Yiteng Tu , Weihang Su , Yujia Zhou , Yiqun Liu , Qingyao Ai

The rapid advancements in artificial intelligence (AI) have revolutionized smart healthcare, driving innovations in wearable technologies, continuous monitoring devices, and intelligent diagnostic systems. However, security, explainability,…

Machine Learning · Computer Science 2024-10-02 Prasenjit Maji , Amit Kumar Mondal , Hemanta Kumar Mondal , Saraju P. Mohanty

Breast cancer is a significant health concern affecting millions of women worldwide. Accurate survival risk stratification plays a crucial role in guiding personalised treatment decisions and improving patient outcomes. Here we present…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Raktim Kumar Mondol , Ewan K. A. Millar , Arcot Sowmya , Erik Meijering

Multiobjective feature selection seeks to determine the most discriminative feature subset by simultaneously optimizing two conflicting objectives: minimizing the number of selected features and the classification error rate. The goal is to…

Neural and Evolutionary Computing · Computer Science 2025-05-12 Zhenxing Zhang , Qianxiang An , Yilei Wang , Chenfeng Wu , Baoling Dong , Chunjie Zhou

The population-based optimization algorithms have provided promising results in feature selection problems. However, the main challenges are high time complexity. Moreover, the interaction between features is another big challenge in FS…

Neural and Evolutionary Computing · Computer Science 2021-10-26 Motahare Namakin , Modjtaba Rouhani , Mostafa Sabzekar

We propose RoBiRank, a ranking algorithm that is motivated by observing a close connection between evaluation metrics for learning to rank and loss functions for robust classification. The algorithm shows a very competitive performance on…

Machine Learning · Statistics 2014-08-22 Hyokun Yun , Parameswaran Raman , S. V. N. Vishwanathan

Machine and deep learning have grown in popularity and use in biological research over the last decade but still present challenges in interpretability of the fitted model. The development and use of metrics to determine features driving…

Machine Learning · Statistics 2025-07-31 Daniel Claborne , Javier Flores , Samantha Erwin , Luke Durell , Rachel Richardson , Ruby Fore , Lisa Bramer

In this paper a data mining approach for variable selection and knowledge extraction from datasets is presented. The approach is based on unguided symbolic regression (every variable present in the dataset is treated as the target variable…

Neural and Evolutionary Computing · Computer Science 2013-09-24 Michael Kommenda , Gabriel Kronberger , Christoph Feilmayr , Michael Affenzeller

Effective data selection is essential for pretraining large language models (LLMs), enhancing efficiency and improving generalization to downstream tasks. However, existing approaches often require leveraging external pretrained models,…

Machine Learning · Computer Science 2026-02-04 Jie Hao , Rui Yu , Wei Zhang , Huixia Wang , Jie Xu , Mingrui Liu

Feature selection is frequently used as a pre-processing step to machine learning. It is a process of choosing a subset of original features so that the feature space is optimally reduced according to a certain evaluation criterion. The…

Computer Vision and Pattern Recognition · Computer Science 2014-01-07 Vijendra Singh , Shivani Pathak

Genetic Programming has been very successful in solving a large area of problems but its use as a machine learning algorithm has been limited so far. One of the reasons is the problem of overfitting which cannot be solved or suppresed as…

Neural and Evolutionary Computing · Computer Science 2015-05-05 Jan Žegklitz , Petr Pošík