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We study numerically the effects of time delay in networks of delay-coupled excitable FitzHugh Nagumo systems with dissipation. The generation of periodic self-sustained oscillations and its threshold are analyzed depending on the…

Adaptation and Self-Organizing Systems · Physics 2023-07-19 A. V. Bukh , I. A. Shepelev , E. M. Elizarov , S. S. Muni , E. Schöll , G. I. Strelkova

The dynamical responses of complex neuronal networks to external stimulus injected on a \emph{single} neuron are investigated. Stimulating the largest-degree neuron in the network, it is found that as the intensity of the stimulus…

Chaotic Dynamics · Physics 2016-04-13 Mengjiao Chen , Weijie Lin , Hengtong Wang , Wei Ren , Xingang Wang

Neuronal excitability is the phenomena that describes action potential generation due to a stimulus input. Commonly, neuronal excitability is divided into two classes: Type I and Type II, both having different properties that affect…

Neurons and Cognition · Quantitative Biology 2020-11-03 Jantine A. C. Broek , Guillaume Drion

The effect of a high-frequency signal on the FitzHugh-Nagumo excitable model is analyzed. We show that the firing rate is diminished as the ratio of the high-frequency amplitude to its frequency is increased. Moreover, it is demonstrated…

Statistical Mechanics · Physics 2016-08-16 David Cubero , José Pablo Baltanás , Jesús Casado-Pascual

We study the phenomenological model of ensemble of two FitzHugh-Nagumo neuron-like elements with symmetric excitatory couplings. The main advantage of proposed model is the new approach to model of coupling which is implemented by smooth…

Dynamical Systems · Mathematics 2018-12-05 Alexander G. Korotkov , Alexey O. Kazakov , Tatiana A. Levanova , Grigory V. Osipov

We analyze the effect of weak-noise-induced transitions on the dynamics of the FitzHugh-Nagumo neuron model in a bistable state consisting of a stable fixed point and a stable unforced limit cycle. Bifurcation and slow-fast analysis give…

Dynamical Systems · Mathematics 2017-06-02 Marius E. Yamakou , Jürgen Jost

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

Neurons and Cognition · Quantitative Biology 2015-07-30 Lianchun Yu , Longfei Wang , Fei Jia , Duojie Jia

This article communicates results on regular depolarization cascades in periodically-kicked feedforward chains of excitable two-dimensional FitzHugh-Nagumo systems driven by sufficiently strong excitatory forcing at the front node. The…

Dynamical Systems · Mathematics 2021-12-21 B. Ambrosio , S. M. Mintchev

The use of high-frequency currents in neurostimulation has received increased attention in recent years due to its varied effects on tissues and cells. Nonlinear differential equations are commonly used as models for Neurons, and averaging…

Analysis of PDEs · Mathematics 2025-12-29 Eduardo Cerpa , Matías Courdurier , Esteban Hernández , Leonel E. Medina , Esteban Paduro

Periodic pulse train stimulation is generically used to study the function of the nervous system and to counteract disease-related neuronal activity, e.g., collective periodic neuronal oscillations. The efficient control of neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-08-05 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

This paper studies the phenomenon of conduction block in model neurons using high-frequency biphasic stimulation (HFBS). The focus is investigating the triggering of undesired onset action potentials when the HFBS is turned on. The approach…

Neurons and Cognition · Quantitative Biology 2025-12-29 Eduardo Cerpa , Nathaly Corrales , Matías Courdurier , Leonel E. Medina , Esteban Paduro

According to the theory of efficient coding, sensory systems are adapted to represent natural scenes with high fidelity and at minimal metabolic cost. Testing this hypothesis for sensory structures performing non-linear computations on high…

Neurons and Cognition · Quantitative Biology 2018-04-13 Ulisse Ferrari , Christophe Gardella , Olivier Marre , Thierry Mora

Electrical coupling between neurons is broadly present across brain areas and is typically assumed to synchronize network activity. However, intrinsic properties of the coupled cells can complicate this simple picture. Many cell types with…

Adaptation and Self-Organizing Systems · Physics 2018-01-19 Thomas Chartrand , Mark S. Goldman , Timothy J. Lewis

Understanding how the dynamics of neural networks is shaped by the computations they perform is a fundamental question in neuroscience. Recently, the framework of efficient coding proposed a theory of how spiking neural networks can compute…

Neurons and Cognition · Quantitative Biology 2022-10-25 Veronika Koren , Stefano Panzeri

To study information processing in the brain, neuroscientists manipulate experimental stimuli while recording participant brain activity. They can then use encoding models to find out which brain "zone" (e.g. which region of interest,…

Neurons and Cognition · Quantitative Biology 2022-02-22 Mariya Toneva , Jennifer Williams , Anand Bollu , Christoph Dann , Leila Wehbe

We analyze the response of the Hodgkin-Huxley neuron to a large number of uncorrelated stochastic inhibitory and excitatory post-synaptic spike trains. In order to clarify the various mechanisms responsible for noise-induced spike…

Disordered Systems and Neural Networks · Physics 2007-05-23 Alessandro Torcini , Stefano Luccioli , Thomas Kreuz

We demonstrate that the information contained in the spike occurrence times of a population of neurons can be broken up into a series of terms, each of which reflect something about potential coding mechanisms. This is possible in the…

Biological Physics · Physics 2007-05-23 S. Panzeri , S. R. Schultz

We propose a nonlinear one-dimensional FitzHugh--Nagumo neuronal model with an asymmetric potential driven by both a high-frequency and a low-frequency signal. Our numerical analysis focuses on the influence of a state-dependent time delay…

Chaotic Dynamics · Physics 2025-01-14 M. Siewe Siewe , S. Rajasekar , Mattia Coccolo , Miguel A. F. Sanjuán

The neural coding is yet to be discovered. The neuronal operational modes that arise with fixed inputs but with varying degrees of stimulation help to elucidate their coding properties. In neurons receiving {\it in vivo} stimulation, we…

Neurons and Cognition · Quantitative Biology 2025-11-05 Lindsey Knowles , Cesar Ceballos , Rodrigo Pena