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Clustering high-dimensional data often requires some form of dimensionality reduction, where clustered variables are separated from "noise-looking" variables. We cast this problem as finding a low-dimensional projection of the data which is…

Machine Learning · Statistics 2016-08-30 Nicolas Flammarion , Balamurugan Palaniappan , Francis Bach

Disentangled representation learning aims to uncover latent variables underlying the observed data, and generally speaking, rather strong assumptions are needed to ensure identifiability. Some approaches rely on sufficient changes on the…

Machine Learning · Computer Science 2025-03-04 Zijian Li , Shunxing Fan , Yujia Zheng , Ignavier Ng , Shaoan Xie , Guangyi Chen , Xinshuai Dong , Ruichu Cai , Kun Zhang

Gene expression and phenotype association can be affected by potential unmeasured confounders from multiple sources, leading to biased estimates of the associations. Since genetic variants largely explain gene expression variations, they…

Methodology · Statistics 2019-10-23 Jiarui Lu , Hongzhe Li

We investigate structured sparsity methods for variable selection in regression problems where the target depends nonlinearly on the inputs. We focus on general nonlinear functions not limiting a priori the function space to additive…

Machine Learning · Statistics 2018-05-17 Magda Gregorová , Alexandros Kalousis , Stéphane Marchand-Maillet

We consider the problem of estimating a sparse multi-response regression function, with an application to expression quantitative trait locus (eQTL) mapping, where the goal is to discover genetic variations that influence gene-expression…

Machine Learning · Statistics 2012-10-01 Seyoung Kim , Eric P. Xing

We consider a Gaussian sequence space model $X_{\lambda}=f_{\lambda} + \xi_{\lambda},$ where $\xi $ has a diagonal covariance matrix $\Sigma=\diag(\sigma_\lambda ^2)$. We consider the situation where the parameter vector $(f_{\lambda})$ is…

Statistics Theory · Mathematics 2013-12-23 Laurent Cavalier , Markus Reiß

In many problem settings, parameter vectors are not merely sparse but dependent in such a way that non-zero coefficients tend to cluster together. We refer to this form of dependency as "region sparsity." Classical sparse regression…

Machine Learning · Statistics 2019-01-28 Anqi Wu , Oluwasanmi Koyejo , Jonathan W. Pillow

We develop a set of variable selection methods for the Cox model under interval censoring, in the ultra-high dimensional setting where the dimensionality can grow exponentially with the sample size. The methods select covariates via a…

Methodology · Statistics 2024-05-03 Daewoo Pak , Jianrui Zhang , Di Wu , Haolei Weng , Chenxi Li

In high-dimensional survival analysis, effective variable selection is crucial for both model interpretation and predictive performance. This paper investigates Cox regression with lasso and adaptive lasso penalties in genomic datasets…

Methodology · Statistics 2025-07-02 Pilar González-Barquero , Rosa E. Lillo , Álvaro Méndez-Civieta

We present sparse tree-based and list-based density estimation methods for binary/categorical data. Our density estimation models are higher dimensional analogies to variable bin width histograms. In each leaf of the tree (or list), the…

Machine Learning · Statistics 2023-11-16 Siong Thye Goh , Lesia Semenova , Cynthia Rudin

Mixtures of matrix Gaussian distributions provide a probabilistic framework for clustering continuous matrix-variate data, which are becoming increasingly prevalent in various fields. Despite its widespread adoption and successful…

Computation · Statistics 2023-07-21 Andrea Cappozzo , Alessandro Casa , Michael Fop

Sparse deep learning aims to address the challenge of huge storage consumption by deep neural networks, and to recover the sparse structure of target functions. Although tremendous empirical successes have been achieved, most sparse deep…

Machine Learning · Statistics 2020-11-17 Jincheng Bai , Qifan Song , Guang Cheng

Revealing relationships between genes and disease phenotypes is a critical problem in biomedical studies. This problem has been challenged by the heterogeneity of diseases. Patients of a perceived same disease may form multiple subgroups,…

Methodology · Statistics 2022-11-30 Yifan Sun , Ziye Luo , Xinyan Fan

For high-dimensional omics data, sparsity-inducing regularization methods such as the Lasso are widely used and often yield strong predictive performance, even in settings when the assumption of sparsity is likely violated. We demonstrate…

Methodology · Statistics 2025-02-13 Andrea Bratsberg , Magne Thoresen , Jelle J. Goeman

In many statistical modeling problems, such as classification and regression, it is common to encounter sparse and blocky coefficients. Sparse fused Lasso is specifically designed to recover these sparse and blocky structured features,…

Statistics Theory · Mathematics 2024-05-30 Xiaofei Wu , Rongmei Liang , Zhimin Zhang , Zhenyu Cui

Cellwise outliers are widespread in data and traditional robust methods may fail when applied to datasets under such contamination. We propose a variable selection procedure, that uses a pairwise robust estimator to obtain an initial…

Methodology · Statistics 2023-09-06 Peng Su , Garth Tarr , Samuel Muller

Many forest management planning decisions are based on information about the number of trees by species and diameter per unit area. This information is commonly summarized in a stand table, where a stand is defined as a group of forest…

Applications · Statistics 2014-11-04 Andrew O. Finley , Sudipto Banerjee , Aaron R. Weiskittel , Chad Babcock , Bruce D. Cook

Fixed effects models are very flexible because they do not make assumptions on the distribution of effects and can also be used if the heterogeneity component is correlated with explanatory variables. A disadvantage is the large number of…

Methodology · Statistics 2015-12-17 Moritz Berger , Gerhard Tutz

High-dimensional learning problems, where the number of features exceeds the sample size, often require sparse regularization for effective prediction and variable selection. While established for fully supervised data, these techniques…

Machine Learning · Computer Science 2026-01-01 The Tien Mai , Mai Anh Nguyen , Trung Nghia Nguyen

In many high dimensional classification or regression problems set in a biological context, the complete identification of the set of informative features is often as important as predictive accuracy, since this can provide mechanistic…

Machine Learning · Computer Science 2020-03-02 Yuxin Sun , Benny Chain , Samuel Kaski , John Shawe-Taylor