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In this paper it is shown that statistical mechanics in the form of thermodynamic entropy can be used as a measure of the severity of individual injuries (AIS), and that the correct way to account for multiple injuries is to sum the…
The Injury Severity Score (ISS) is a standard aggregate indicator of the overall severity of multiple injuries to the human body. This score is calculated by summing the squares of the three highest values of the Abbreviated Injury Scale…
In the real world, the severity of traumatic injuries are measured using the Abbreviated Injury Scale (AIS). However the AIS scale cannot currently be computed by using finite element human computer models, which calculate a maximum…
Traumatic injuries are measured using the Abbreviated Injury Scale (AIS), which is a risk to life scale. New human computer models use stresses and strains to evaluate whether serious or fatal injuries are reached, unfortunately these…
Traumatic brain injury (TBI) presents a significant public health challenge, often resulting in mortality or lasting disability. Predicting outcomes such as mortality and Functional Status Scale (FSS) scores can enhance treatment strategies…
Recently, it has been shown that the transition rates of the illness-death model (IDM) for chronic conditions are related to the percentages of people in the states by a three-dimensional system of differential equations [Bri24]. The aim of…
We propose a Multi-vAlue Rule Set (MRS) model for in-hospital predicting patient mortality. Compared to rule sets built from single-valued rules, MRS adopts a more generalized form of association rules that allows multiple values in a…
In clinical trials, the observation of participant outcomes may frequently be hindered by death, leading to ambiguity in defining a scientifically meaningful final outcome for those who die. Principal stratification methods are valuable…
Automatic assessment of impairment and disease severity is a key challenge in data-driven medicine. We propose a novel framework to address this challenge, which leverages AI models trained exclusively on healthy individuals. The…
Acute stroke lesion segmentation tasks are of great clinical interest as they can help doctors make better informed treatment decisions. Magnetic resonance imaging (MRI) is time demanding but can provide images that are considered gold…
Two problems that arise in making causal inferences for non-mortality outcomes such as bronchopulmonary dysplasia (BPD) are unmeasured confounding and censoring by death, i.e., the outcome is only observed when subjects survive. In…
Stroke is the second leading cause of mortality worldwide. Immediate attention and diagnosis play a crucial role regarding patient prognosis. The key to diagnosis consists in localizing and delineating brain lesions. Standard stroke…
Stroke is a significant cause of mortality and morbidity, necessitating early predictive strategies to minimize risks. Traditional methods for evaluating patients, such as Acute Physiology and Chronic Health Evaluation (APACHE II, IV) and…
In the medical image analysis field, precise quantification of curve tortuosity plays a critical role in the auxiliary diagnosis and pathological assessment of various diseases. In this study, we propose a novel framework for tortuosity…
Vehicles equipped with automated driving capabilities have shown potential to improve safety and operations. Advanced driver assistance systems (ADAS) and automated driving systems (ADS) have been widely developed to support vehicular…
In this article, we use the illness-death model to present a mathematical framework for studying the compression of morbidity (COM) hypothesis. It turns out that questions about COM are completely determined by the transition rates in the…
Weighting methods are used in observational studies to adjust for covariate imbalances between treatment and control groups. Entropy balancing (EB) is an alternative to inverse probability weighting with an estimated propensity score. The…
As populations age, the rise of multimorbidity poses a significant healthcare challenge. However, our ability to quantitatively forecast the progression of multimorbidity remains limited. Leveraging a nationwide dataset comprising…
A collision hazard measure that has the essential characteristics to provide a measurement of safety that will be useful to AV developers, traffic infrastructure developers and managers, regulators and the public is introduced here. The…
Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…