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Nonlinear dynamic models are widely used for characterizing functional forms of processes that govern complex biological pathway systems. Over the past decade, validation and further development of these models became possible due to data…

Methodology · Statistics 2019-08-13 Itai Dattner , Shota Gugushvili , Harold Ship , Eberhard O. Voit

Business process simulation is a versatile technique to estimate the performance of a process under multiple scenarios. This, in turn, allows analysts to compare alternative options to improve a business process. A common roadblock for…

Software Engineering · Computer Science 2020-03-30 Manuel Camargo , Marlon Dumas , Oscar González-Rojas

A fundamental problem in science and engineering is designing optimal control policies that steer a given system towards a desired outcome. This work proposes Control Physics-Informed Neural Networks (Control PINNs) that simultaneously…

Machine Learning · Computer Science 2022-08-22 Jostein Barry-Straume , Arash Sarshar , Andrey A. Popov , Adrian Sandu

A special aspect of parameter identification in finite-strain elasto-plasticity is considered. Namely, we analyze the impact of the measurement errors on the resulting set of material parameters. In order to define the sensitivity of…

Applications · Statistics 2021-03-15 A. V. Shutov , A. A. Kaygorodtseva

Biological molecular machines convert free energy between different forms in cells, often at high efficiency. Optimal control theory provides a framework to elucidate design principles governing energetically efficient driving. Here, we use…

Biological Physics · Physics 2025-06-12 W. Callum Wareham , David A. Sivak

We derive asymptotically optimal statistical decision rules for discrete choice problems when payoffs depend on a partially-identified parameter $\theta$ and the decision maker can use a point-identified parameter $\mu$ to deduce…

Econometrics · Economics 2025-12-19 Timothy Christensen , Hyungsik Roger Moon , Frank Schorfheide

Network protocol fingerprinting is used to identify a protocol implementation by analyzing its input-output behavior. Traditionally, fingerprinting operates under a closed-world assumption, where models of all implementations are assumed to…

Cryptography and Security · Computer Science 2026-01-30 Loes Kruger , Paul Kobialka , Andrea Pferscher , Einar Broch Johnsen , Sebastian Junges , Jurriaan Rot

Quantum sensors can show unprecedented sensitivities, provided they are controlled in a very specific, optimal way. Here, we consider a spin sensor of time-varying fields in the presence of dephasing noise, and we show that the problem of…

Quantum Physics · Physics 2024-07-10 S. Hernández-Gómez , F. Balducci , G. Fasiolo , P. Cappellaro , N. Fabbri , A. Scardicchio

Real world evolves in continuous time but computations are done from finite samples. Therefore, we study algorithms using finite observations in continuous-time linear dynamical systems. We first study the system identification problem, and…

Systems and Control · Electrical Eng. & Systems 2025-09-30 Hongyi Zhou , Jingwei Li , Jingzhao Zhang

The system identification problem is to estimate dynamical parameters from the output data, obtained by performing measurements on the output fields. We investigate system identification for quantum linear systems. Our main objectives are…

Quantum Physics · Physics 2017-12-25 Matthew Levitt , Mădălin Guţă , Theodore Kypraios

We apply innovative mathematical tools coming from optimal control theory to improve theoretical and experimental techniques in Magnetic Resonance Imaging (MRI). This approach allows us to explore and to experimentally reach the physical…

Quantum Physics · Physics 2017-09-11 E. Van-Reeth , H. Ratiney , M. Lapert , S. J. Glaser , D. Sugny

Computing an optimal classification tree that provably maximizes training performance within a given size limit, is NP-hard, and in practice, most state-of-the-art methods do not scale beyond computing optimal trees of depth three.…

Machine Learning · Computer Science 2025-01-15 Catalin E. Brita , Jacobus G. M. van der Linden , Emir Demirović

We describe how a single-particle tracking experiment should be designed in order for its recorded trajectories to contain the most information about a tracked particle's diffusion coefficient. The precision of estimators for the diffusion…

Biological Physics · Physics 2016-08-10 Christian L. Vestergaard

Simulation is a useful tool in situations where training data for machine learning models is costly to annotate or even hard to acquire. In this work, we propose a reinforcement learning-based method for automatically adjusting the…

Machine Learning · Computer Science 2019-05-15 Nataniel Ruiz , Samuel Schulter , Manmohan Chandraker

Computational models of human language often involve combinatorial problems. For instance, a probabilistic parser may marginalize over exponentially many trees to make predictions. Algorithms for such problems often employ dynamic…

Computation and Language · Computer Science 2021-09-16 Tim Vieira , Ryan Cotterell , Jason Eisner

Many applications of computational fluid dynamics require multiple simulations of a flow under different input conditions. In this paper, a numerical algorithm is developed to efficiently determine a set of such simulations in which the…

Numerical Analysis · Mathematics 2017-05-29 Max Gunzburger , Nan Jiang , Zhu Wang

In this letter we propose the use of physics techniques for entropy determination on constrained parameter optimization problems. The main feature of such techniques, the construction of an unbiased walk on energy space, suggests their use…

Statistical Mechanics · Physics 2009-11-07 A. R. Lima , M. Argollo de Menezes

Fingerprint recognition systems, which rely on the unique characteristics of human fingerprints, are essential in modern security and verification applications. Accurate minutiae extraction, a critical step in these systems, depends on the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Raffaele Cappelli

A recently proposed method for computer simulations in the isothermal-isobaric (NPT) ensemble, based on Langevin-type equations of motion for the particle coordinates and the ``piston'' degree of freedom, is re-derived by straightforward…

Soft Condensed Matter · Physics 2016-08-31 A. Kolb , B. Duenweg

Bayesian optimal experiments that maximize the information gained from collected data are critical to efficiently identify behavioral models. We extend a seminal method for designing Bayesian optimal experiments by introducing two…

Applications · Statistics 2025-03-19 Stefano Balietti , Brennan Klein , Christoph Riedl
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