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An important problem in evolutionary biology is to reconstruct the evolutionary history of a set $X$ of species. This history is often represented as a phylogenetic network, that is, a connected graph with leaves labelled by elements in $X$…

Combinatorics · Mathematics 2017-02-01 Leo van Iersel , Vincent Moulton

Phylogenetic networks are a generalization of phylogenetic trees that are used in biology to represent reticulate or non-treelike evolution. Recently, several algorithms have been developed which aim to construct phylogenetic networks from…

Populations and Evolution · Quantitative Biology 2011-10-05 K. T. Huber , V. Moulton

When hybridization or other forms of lateral gene transfer have occurred, evolutionary relationships of species are better represented by phylogenetic networks than by trees. While inference of such networks remains challenging, several…

Populations and Evolution · Quantitative Biology 2024-01-15 Elizabeth S. Allman , Hector Baños , Marina Garrote-Lopez , John A. Rhodes

Phylogenetic networks are graphs that are used to represent evolutionary relationships between different taxa. They generalize phylogenetic trees since for example, unlike trees, they permit lineages to combine. Recently, there has been…

Populations and Evolution · Quantitative Biology 2025-08-05 Katharina T. Huber , Leo van Iersel , Mark Jones , Vincent Moulton , Leonie Veenema - Nipius

The reconstruction of phylogenetic networks is an important but challenging problem in phylogenetics and genome evolution, as the space of phylogenetic networks is vast and cannot be sampled well. One approach to the problem is to solve the…

Populations and Evolution · Quantitative Biology 2023-04-14 Louxin Zhang , Niloufar Abhari , Caroline Colijn , Yufeng Wu

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of…

The inference of phylogenetic networks, which model complex evolutionary processes including hybridization and gene flow, remains a central challenge in evolutionary biology. Until now, statistically consistent inference methods have been…

Populations and Evolution · Quantitative Biology 2025-10-14 Niels Holtgrefe , Elizabeth S. Allman , Hector Baños , Leo van Iersel , Vincent Moulton , John A. Rhodes , Kristina Wicke

One strategy for reconstruction of phylogenetic networks is to solve the phylogenetic network problem, which involves inferring phylogenetic trees first and subsequently computing the smallest phylogenetic network that displays all the…

Combinatorics · Mathematics 2023-09-26 Laurent Bulteau , Louxin Zhang

Binets and trinets are phylogenetic networks with two and three leaves, respectively. Here we consider the problem of deciding if there exists a binary level-1 phylogenetic network displaying a given set $\mathcal{T}$ of binary binets or…

Data Structures and Algorithms · Computer Science 2014-11-26 Katharina Huber , Leo van Iersel , Vincent Moulton , Celine Scornavacca , Taoyang Wu

Evolutionary histories for species that cross with one another or exchange genetic material can be represented by leaf-labelled, directed graphs called phylogenetic networks. A major challenge in the burgeoning area of phylogenetic networks…

Data Structures and Algorithms · Computer Science 2021-09-24 Leo van Iersel , Sjors Kole , Vincent Moulton , Leonie Nipius

Semi-directed networks provide a graphical structure for describing the evolutionary history of organisms in the presence of hybridization. We introduce two algorithms for reconstructing semi-directed level-1 phylogenetic networks from…

Genomics · Quantitative Biology 2025-07-23 Sophia Huebler , Rachel Morris , Joseph Rusinko

In phylogenetics, a central problem is to infer the evolutionary relationships between a set of species $X$; these relationships are often depicted via a phylogenetic tree -- a tree having its leaves univocally labeled by elements of $X$…

Data Structures and Algorithms · Computer Science 2016-04-12 Julien Baste , Christophe Paul , Ignasi Sau , Celine Scornavacca

Inference of phylogenetic networks is of increasing interest in the genomic era. However, the extent to which phylogenetic networks are identifiable from various types of data remains poorly understood, despite its crucial role in…

Populations and Evolution · Quantitative Biology 2025-05-01 Elizabeth S. Allman , Cecile Ane , Hector Banos , John A. Rhodes

Phylogenetic networks can represent evolutionary events that cannot be described by phylogenetic trees, such as hybridization, introgression, and lateral gene transfer. Studying phylogenetic networks under a statistical model of DNA…

Populations and Evolution · Quantitative Biology 2024-07-17 M. Frohn , N. Holtgrefe , L. van Iersel , M. Jones , S. Kelk

A phylogenetic tree is a graphical representation of an evolutionary history of taxa in which the leaves correspond to the taxa and the non-leaves correspond to speciations. One of important problems in phylogenetic analysis is to assemble…

Combinatorics · Mathematics 2022-02-25 Hiroshi Hirai , Yuni Iwamasa

Phylogenetic networks generalize phylogenetic trees by allowing the modelization of events of reticulate evolution. Among the different kinds of phylogenetic networks that have been proposed in the literature, the subclass of binary…

Data Structures and Algorithms · Computer Science 2020-07-01 Gabriel Cardona , Joan Carles Pons , Celine Scornavacca

Phylogenetic networks model reticulate evolutionary histories. The last two decades have seen an increased interest in establishing mathematical results and developing computational methods for inferring and analyzing these networks. A…

Populations and Evolution · Quantitative Biology 2016-06-24 Jiafan Zhu , Yun Yu , Luay Nakhleh

Phylogenetic networks generalize phylogenetic trees, and have been introduced in order to describe evolution in the case of transfer of genetic material between coexisting species. There are many classes of phylogenetic networks, which can…

Combinatorics · Mathematics 2020-03-13 Mathilde Bouvel , Philippe Gambette , Marefatollah Mansouri

Phylogenetic trees (i.e. evolutionary trees, additive trees or X-trees) play a key role in the processes of modeling and representing species evolution. Genome evolution of a given group of species is usually modeled by a species…

Populations and Evolution · Quantitative Biology 2023-01-03 Vladimir Makarenkov , Gayane S. Barseghyan , Nadia Tahiri

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

Populations and Evolution · Quantitative Biology 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel
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