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Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Rui Aguiar , Jon Braatz

Whole-Slide Images (WSIs) have revolutionized medical analysis by presenting high-resolution images of the whole tissue slide. Despite avoiding the physical storage of the slides, WSIs require considerable data volume, which makes the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Yu Mao , Jun Wang , Nan Guan , Chun Jason Xue

Automatic instance segmentation of glomeruli within kidney Whole Slide Imaging (WSI) is essential for clinical research in renal pathology. In computer vision, the end-to-end instance segmentation methods (e.g., Mask-RCNN) have shown their…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Aadarsh Jha , Haichun Yang , Ruining Deng , Meghan E. Kapp , Agnes B. Fogo , Yuankai Huo

Semi-supervised segmentation remains challenging in medical imaging since the amount of annotated medical data is often scarce and there are many blurred pixels near the adhesive edges or in the low-contrast regions. To address the issues,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-29 Yicheng Wu , Zhonghua Wu , Qianyi Wu , Zongyuan Ge , Jianfei Cai

We consider the problem of segmenting an image into superpixels in the context of $k$-means clustering, in which we wish to decompose an image into local, homogeneous regions corresponding to the underlying objects. Our novel approach…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Jianchao Zhang , Angelica I. Aviles-Rivero , Daniel Heydecker , Xiaosheng Zhuang , Raymond Chan , Carola-Bibiane Schönlieb

This paper presents a deep learning framework for the multi-class classification of gastrointestinal abnormalities in Video Capsule Endoscopy (VCE) frames. The aim is to automate the identification of ten GI abnormality classes, including…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Aman Sagar , Preeti Mehta , Monika Shrivastva , Suchi Kumari

Machine learning algorithms underpin modern diagnostic-aiding software, which has proved valuable in clinical practice, particularly in radiology. However, inaccuracies, mainly due to the limited availability of clinical samples for…

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Quantitative Methods · Quantitative Biology 2019-04-24 Weikang Wang , David A. Taft , Yi-Jiun Chen , Jingyu Zhang , Callen T. Wallace , Min Xu , Simon C. Watkins , Jianhua Xing

Graph signal processing (GSP) is becoming a major tool in biomedical signal and image analysis. In most GSP techniques, graph structures and edge weights have been typically set via statistical and computational methods. More recently,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Asmaa M. Elwer , Muhammad A. Rushdi , Mahmoud H. Annaby

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh

Abnormalities in retinal fundus images may indicate certain pathologies such as diabetic retinopathy, hypertension, stroke, glaucoma, retinal macular edema, venous occlusion, and atherosclerosis, making the study and analysis of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Yuzhuo Chen , Zetong Chen , Yuanyuan Liu

The analysis of retinal images for the diagnosis of various diseases is one of the emerging areas of research. Recently, the research direction has been inclined towards investigating several changes in retinal blood vessels in subjects…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mehwish Mehmood , Shahzaib Iqbal , Tariq Mahmood Khan , Ivor Spence , Muhammad Fahim

Previous works on segmentation of SEM (scanning electron microscope) blood cell image ignore the semantic segmentation approach of whole-slide blood cell segmentation. In the proposed work, we address the problem of whole-slide blood cell…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Muhammad Shahzad , Arif Iqbal Umar , Muazzam A. Khan , Syed Hamad Shirazi , Zakir Khan , Waqas Yousaf

Breast-conserving surgery (BCS) aims to completely remove malignant lesions while maximizing healthy tissue preservation. Intraoperative margin assessment is essential to achieve a balance between thorough cancer resection and tissue…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Pouya Afshin , David Helminiak , Tongtong Lu , Tina Yen , Julie M. Jorns , Mollie Patton , Bing Yu , Dong Hye Ye

Deep learning-based medical image segmentation technology aims at automatic recognizing and annotating objects on the medical image. Non-local attention and feature learning by multi-scale methods are widely used to model network, which…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Bo Wang , Lei Wang , Junyang Chen , Zhenghua Xu , Thomas Lukasiewicz , Zhigang Fu

The detection and segmentation of white blood cells in blood smear images is a key step in medical diagnostics, supporting various downstream tasks such as automated blood cell counting, morphological analysis, cell classification, and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Michael Deutges , Chen Yang , Raheleh Salehi , Nassir Navab , Carsten Marr , Ario Sadafi

In-vivo optical microscopy is advancing into routine clinical practice for non-invasively guiding diagnosis and treatment of cancer and other diseases, and thus beginning to reduce the need for traditional biopsy. However, reading and…

Image and Video Processing · Electrical Eng. & Systems 2020-01-07 Kivanc Kose , Alican Bozkurt , Christi Alessi-Fox , Melissa Gill , Caterina Longo , Giovanni Pellacani , Jennifer Dy , Dana H. Brooks , Milind Rajadhyaksha

Medical image segmentation aims to identify anatomical structures at the voxel-level. Segmentation accuracy relies on distinguishing voxel differences. Compared to advancements achieved in studies of the inter-class variance, the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Yali Bi , Enyu Che , Yinan Chen , Yuanpeng He , Jingwei Qu

Sturge-Weber syndrome (SWS) is a vascular malformation disease, and it may cause blindness if the patient's condition is severe. Clinical results show that SWS can be divided into two types based on the characteristics of scleral blood…

Image and Video Processing · Electrical Eng. & Systems 2020-10-26 Chang Yao , Jingyu Tang , Menghan Hu , Yue Wu , Wenyi Guo , Qingli Li , Xiao-Ping Zhang

Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li
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