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Diffusion models have impressive image generation capability, but low-quality generations still exist, and their identification remains challenging due to the lack of a proper sample-wise metric. To address this, we propose BayesDiff, a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Siqi Kou , Lei Gan , Dequan Wang , Chongxuan Li , Zhijie Deng

This study proposes a novel approach to quantifying uncertainties of constitutive relations inferred from noisy experimental data using inverse modelling. We focus on electrochemical systems in which charged species (e.g., Lithium ions) are…

Chemical Physics · Physics 2020-03-12 Athinthra Sethurajan , Sergey Krachkovskiy , Gillian Goward , Bartosz Protas

We introduce and demonstrate a new paradigm for quantitative parameter mapping in MRI. Parameter mapping techniques, such as diffusion MRI and quantitative MRI, have the potential to robustly and repeatably measure biologically-relevant…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Moucheng Xu , Yukun Zhou , Tobias Goodwin-Allcock , Kimia Firoozabadi , Joseph Jacob , Daniel C. Alexander , Paddy J. Slator

Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are…

Medical Physics · Physics 2020-08-14 Valerij G. Kiselev

Quantifying the myelin sheath radius of myelinated axons in vivo is important for understanding, diagnosing, and monitoring various neurological disorders. Despite advancements in diffusion MRI (dMRI) microstructure techniques, there are…

The topic of deep learning has seen a surge of interest in recent years both within and outside of the field of Statistics. Deep models leverage both nonlinearity and interaction effects to provide superior predictions in many cases when…

Methodology · Statistics 2020-09-18 Paul A. Parker , Scott H. Holan

The comprehensive integration of machine learning healthcare models within clinical practice remains suboptimal, notwithstanding the proliferation of high-performing solutions reported in the literature. A predominant factor hindering…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Ling Huang , Su Ruan , Yucheng Xing , Mengling Feng

Magnetic Resonance Imaging (MRI) is highly susceptible to motion artifacts due to the extended acquisition times required for k-space sampling. These artifacts can compromise diagnostic utility, particularly for dynamic imaging. We propose…

Image and Video Processing · Electrical Eng. & Systems 2025-07-04 Frederic Wang , Jonathan I. Tamir

Advances in architectural design, data availability, and compute have driven remarkable progress in semantic segmentation. Yet, these models often rely on relaxed Bayesian assumptions, omitting critical uncertainty information needed for…

Computer Vision and Pattern Recognition · Computer Science 2026-02-19 M. M. A. Valiuddin , R. J. G. van Sloun , C. G. A. Viviers , P. H. N. de With , F. van der Sommen

The assessment of imaging biomarkers is critical for advancing precision medicine and improving disease characterization. Despite the availability of methods to derive disease heterogeneity metrics in imaging studies, a robust framework for…

Implicit neural representations (INRs) have achieved impressive results for scene reconstruction and computer graphics, where their performance has primarily been assessed on reconstruction accuracy. As INRs make their way into other…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Francisca Vasconcelos , Bobby He , Nalini Singh , Yee Whye Teh

Accurate estimation of intravoxel incoherent motion (IVIM) parameters from diffusion-weighted MRI remains challenging due to the ill-posed nature of the inverse problem and high sensitivity to noise, particularly in the perfusion…

Beyond estimating parameters of interest from data, one of the key goals of statistical inference is to properly quantify uncertainty in these estimates. In Bayesian inference, this uncertainty is provided by the posterior distribution, the…

Machine Learning · Computer Science 2025-01-03 Daniela de Albuquerque , John Pearson

This paper describes a novel nonparametric model for modeling diffusion MRI signals in q-space. In q-space, diffusion MRI signal is measured for a sequence of magnetic strengths (b-values) and magnetic gradient directions (b-vectors). We…

Applications · Statistics 2024-03-13 Arkaprava Roy , Zhou Lan , Zhengwu Zhang

Uncertainty quantification is a critical missing component in radio interferometric imaging that will only become increasingly important as the big-data era of radio interferometry emerges. Since radio interferometric imaging requires…

Instrumentation and Methods for Astrophysics · Physics 2018-09-12 Xiaohao Cai , Marcelo Pereyra , Jason D. McEwen

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

Water diffusion gives rise to micron-scale sensitivity of diffusion MRI (dMRI) to cellular-level tissue structure. Precision medicine and quantitative imaging depend on uncovering the information content of dMRI and establishing its…

Medical Physics · Physics 2026-02-03 Santiago Coelho , Jenny Chen , Filip Szczepankiewicz , Els Fieremans , Dmitry S. Novikov

Uncertainty quantification is critical in scientific inverse problems to distinguish identifiable parameters from those that remain ambiguous given available measurements. The Conditional Diffusion Model-based Inverse Problem Solver (CDI)…

Machine Learning · Computer Science 2026-01-27 Dmitrii Torbunov , Yihui Ren , Lijun Wu , Yimei Zhu

Knowledge of the noise distribution in diffusion MRI is the centerpiece to quantify uncertainties arising from the acquisition process. Accurate estimation beyond textbook distributions often requires information about the acquisition…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Samuel St-Jean , Alberto De Luca , Chantal M. W. Tax , Max A. Viergever , Alexander Leemans

Diffusion models have recently shown remarkable results in magnetic resonance imaging reconstruction. However, the employed networks typically are black-box estimators of the (smoothed) prior score with tens of millions of parameters,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-16 Laurenz Nagler , Martin Zach , Thomas Pock