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Simulation of stochastic spatially-extended systems is a challenging problem. The fundamental quantities in these models are individual entities such as molecules, cells, or animals, which move and react in a random manner. In big systems,…

Quantitative Methods · Quantitative Biology 2024-09-24 Tomás Alarcón , Natalia Briñas-Pascual , Juan Calvo , Pilar Guerrero , Daria Stepanova

Diffusion models have emerged as powerful generative tools with applications in computer vision and scientific machine learning (SciML), where they have been used to solve large-scale probabilistic inverse problems. Traditionally, these…

Open biochemical systems of interacting molecules are ubiquitous in life-related processes. However, established computational methodologies, like molecular dynamics, are still mostly constrained to closed systems and timescales too small…

Quantitative Methods · Quantitative Biology 2025-10-15 Margarita Kostré , Christof Schütte , Frank Noé , Mauricio J. del Razo

This paper is devoted to the study of systems of reaction-cross diffusion equations arising in population dynamics. New results of existence of weak solutions are presented, allowing to treat systems of two equations in which one of the…

Analysis of PDEs · Mathematics 2014-10-28 Laurent Desvillettes , Thomas Lepoutre , Ayman Moussa , Ariane Trescases

Detecting out-of-distribution (OOD) data is critical for machine learning, be it for safety reasons or to enable open-ended learning. However, beyond mere detection, choosing an appropriate course of action typically hinges on the type of…

Machine Learning · Computer Science 2026-04-28 Achref Jaziri , Martin Rogmann , Martin Mundt , Visvanathan Ramesh

We revisit a classical continuum model for the diffusion of multiple species with size-exclusion constraint, which leads to a degenerate nonlinear cross-diffusion system. The purpose of this article is twofold: first, it aims at a…

Analysis of PDEs · Mathematics 2022-08-04 Katharina Hopf , Martin Burger

A second-order accurate in time, positivity-preserving, and unconditionally energy stable operator splitting numerical scheme is proposed and analyzed for the system of reaction-diffusion equations with detailed balance. The scheme is…

Numerical Analysis · Mathematics 2021-09-08 Chun Liu , Cheng Wang , Yiwei Wang

In this work we present the convergence of a positivity preserving semi-discrete finite volume scheme for a coupled system of two non-local partial differential equations with cross-diffusion. The key to proving the convergence result is to…

Numerical Analysis · Mathematics 2020-04-13 José A. Carrillo , Francis Filbet , Markus Schmidtchen

Extensive simulations are performed of the diffusion-limited reaction A$+$B$\to 0$ in one dimension, with initially separated reagents. The reaction rate profile, and the probability distributions of the separation and midpoint of the…

Condensed Matter · Physics 2009-10-22 Stephen Cornell

We investigate a class of systems of partial differential equations with nonlinear cross-diffusion and nonlocal interactions, which are of interest in several contexts in social sciences, finance, biology, and real world applications.…

Analysis of PDEs · Mathematics 2017-10-05 M. Di Francesco , A. Esposito , S. Fagioli

In this work, we show high order splitting methods of integration without negative steps, allowing us to solve numerically irreversible problems, like reaction-diffusion equations. The methods consist in a suitable affine combinations of…

Numerical Analysis · Mathematics 2014-10-21 Mariano De Leo , Diego Rial , Constanza Sanchez de la Vega

The purpose of this article is to investigate the emergence of cross-diffusion in the time evolution of two slow-fast species in competition. A class of triangular cross-diffusion system is obtained as the singular limit of a fast…

Analysis of PDEs · Mathematics 2025-06-25 Elisabetta Brocchieri , Lucilla Corrias

Distributed state estimation (DSE) is considered as a more robust and reliable alternative for centralized state estimation (CSE) in power system. Especially, taking into account the future power grid, so called smart grid in which…

Systems and Control · Electrical Eng. & Systems 2021-04-12 Sajjad Asefi , Elena Gryazina , Helder Leite

Reaction-diffusion processes are the foundational model for a diverse range of complex systems, ranging from biochemical reactions to social agent-based phenomena. The underlying dynamics of these systems occur at the individual…

Statistical Mechanics · Physics 2025-10-15 Mauricio J. del Razo , Margarita Kostré

A novel principle is presented which allows for the proof of bounded weak solutions to a class of physically relevant, strongly coupled parabolic systems exhibiting a formal gradient-flow structure. The main feature of these systems is that…

Analysis of PDEs · Mathematics 2015-06-11 Ansgar Jüngel

A system of degenerate drift-diffusion equations for the electron, hole, and oxygen vacancy densities, coupled to the Poisson equation for the electric potential, is analyzed in a three-dimensional bounded domain with mixed…

Analysis of PDEs · Mathematics 2023-11-29 Ansgar Jüngel , Martin Vetter

We establish the global existence of weak solutions for a two-species cross-diffusion system, set on the 1-dimensional flat torus, in which the evolution of each species is governed by two mechanisms. The first of these is a diffusion which…

Analysis of PDEs · Mathematics 2025-04-28 Alpár R. Mészáros , Guy Parker

The quasi-steady state approximation and time-scale separation are commonly applied methods to simplify models of biochemical reaction networks based on ordinary differential equations (ODEs). The concentrations of the "fast" species are…

Dynamical Systems · Mathematics 2016-05-10 Meritxell Sáez , Carsten Wiuf , Elisenda Feliu

Reaction diffusion systems with Turing instability and mass conservation are studied. In such systems, abrupt decays of stripes follow quasi-stationary states in sequence. At steady state, the distance between stripes is much longer than…

Pattern Formation and Solitons · Physics 2009-11-11 Shuji Ishihara , Mikiya Otsuji , Atsushi Mochizuki

We present new results of existence of global solutions for a class of reaction cross-diffusion systems of two equations presenting a cross-diffusion term in the first equation, and possibly presenting a self-diffusion term in any (or both)…

Analysis of PDEs · Mathematics 2015-03-26 Ariane Trescases