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Range expansion is a universal process in biological systems, and therefore plays a part in biological evolution. Using a quantitative individual-based method based on the stochastic process, we identify that enhancing the inherent…

Populations and Evolution · Quantitative Biology 2022-01-17 Xiaoliang Wang , Andrew Harrison

Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading through spontaneous phenotypic variations is a known concept in…

Populations and Evolution · Quantitative Biology 2020-04-03 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Chronic viral infections can persist in an infected person for decades. From the perspective of the virus, a single infection can span thousands of generations, leading to a highly diverse population of viruses with its own complex…

Populations and Evolution · Quantitative Biology 2023-05-30 Dmitry Gromov , Ethan O. Romero-Severson

The spatial structure of an evolving population affects which mutations become fixed. Some structures amplify selection, increasing the likelihood that beneficial mutations become fixed while deleterious mutations do not. Other structures…

Mutational robustness quantifies the effect of random mutations on fitness. When mutational robustness is high, most mutations do not change fitness or have only a minor effect on it. From the point of view of fitness landscapes, robust…

Populations and Evolution · Quantitative Biology 2019-10-22 Alexander Klug , Su-Chan Park , Joachim Krug

The evolution of species habitat range is an important topic over a wide range of research fields. In higher organisms, habitat range evolution is generally associated with genetic events such as gene duplication. However, the specific…

Molecular Networks · Quantitative Biology 2016-01-11 Kazuhiro Takemoto

Evolutionary dynamics can be studied in well-mixed or structured populations. Population structure typically arises from the heterogeneous distribution of individuals in physical space or on social networks. Here we introduce a new type of…

Populations and Evolution · Quantitative Biology 2009-06-04 Tibor Antal , Hisashi Ohtsuki , John Wakeley , Peter D. Taylor , Martin A. Nowak

In the framework of the paradigmatic prisoner's dilemma, we investigate the evolutionary dynamics of social dilemmas in the presence of "cooperation facilitators". In our model, cooperators and defectors interact as in the classical…

Populations and Evolution · Quantitative Biology 2012-08-02 Mauro Mobilia

Cooperation is ubiquitous across all levels of biological systems ranging from microbial communities to human societies. It, however, seemingly contradicts the evolutionary theory, since cooperators are exploited by free-riders and thus are…

Populations and Evolution · Quantitative Biology 2019-09-23 Yunming Xiao , Bin Wu

Stronger selection implies faster evolution---that is, the greater the force, the faster the change. This apparently self-evident proposition, however, is derived under the assumption that genetic variation within a population is primarily…

Populations and Evolution · Quantitative Biology 2017-08-18 Masahiko Ueda , Nobuto Takeuchi , Kunihiko Kaneko

The relationship between genotype and phenotype plays a crucial role in determining the function and robustness of biological systems. Here the evolution progresses through the change in genotype, whereas the selection is based on the…

Populations and Evolution · Quantitative Biology 2025-02-18 Tuan Minh Pham , Kunihiko Kaneko

A host-parasite model is considered for a population of cells that can be of two types, A or B, and exhibits unilateral reproduction: while a B-cell always splits into two cells of the same type, the two daughter cells of an A-cell can be…

Probability · Mathematics 2013-02-06 Gerold Alsmeyer , Sören Gröttrup

Between-species coevolution, and in particular antagonistic host-parasite coevolution, is a major process shaping within-species diversity. In this paper we investigate the role of various stochastic processes affecting the outcome of the…

Populations and Evolution · Quantitative Biology 2020-12-08 Wolfgang Stephan , Aurélien Tellier

Biological cells replicate their genomes in a well-planned manner. The DNA replication program of an organism determines the timing at which different genomic regions are replicated, with fundamental consequences for cell homeostasis and…

Subcellular Processes · Quantitative Biology 2024-05-28 Florian Pflug , Deepak Bhat , Simone Pigolotti

Molecular phenotypes are important links between genomic information and organismic functions, fitness, and evolution. Complex phenotypes, which are also called quantitative traits, often depend on multiple genomic loci. Their evolution…

Populations and Evolution · Quantitative Biology 2015-06-12 Armita Nourmohammad , Stephan Schiffels , Michael Laessig

We have analyzed the relations between the mutational pressure, recombination and selection pressure in the bit-string model with sexual reproduction. For specific sets of these parameters we have found three phase transitions with one…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Stauffer , S. Cebrat

Random copying is a simple model for population dynamics in the absence of selection, and has been applied to both biological and cultural evolution. In this work, we investigate the effect that spatial structure has on the dynamics. We…

Physics and Society · Physics 2015-05-26 Richard A Blythe

We have simulated the evolution of age structured populations whose individuals represented by their diploid genomes were distributed on a square lattice. The environmental conditions on the whole territory changed simultaneously in the…

Populations and Evolution · Quantitative Biology 2009-11-05 Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

The problem of natural selection in dispersal-structured populations consisting of individuals characterized by different diffusion coefficients is studied. The competition between the organisms is taken into account through the assumption…

Adaptation and Self-Organizing Systems · Physics 2020-05-01 E. Heinsalu , D. Navidad Maeso , M. Patriarca

We define a general class of models representing natural selection between two alleles. The population size and spatial structure are arbitrary, but fixed. Genetics can be haploid, diploid, or otherwise; reproduction can be asexual or…

Populations and Evolution · Quantitative Biology 2021-02-05 Benjamin Allen , Alex McAvoy
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