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Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…
Deep learning approaches deliver state-of-the-art performance in recognition of spatiotemporal human motion data. However, one of the main challenges in these recognition tasks is limited available training data. Insufficient training data…
Generative adversarial networks (GANs) while being very versatile in realistic image synthesis, still are sensitive to the input distribution. Given a set of data that has an imbalance in the distribution, the networks are susceptible to…
Missing data are present in most real world problems and need careful handling to preserve the prediction accuracy and statistical consistency in the downstream analysis. As the gold standard of handling missing data, multiple imputation…
Rare diseases affect a relatively small number of people, which limits investment in research for treatments and cures. Developing an efficient method for rare disease detection is a crucial first step towards subsequent clinical research.…
The training of generative adversarial networks (GANs) is usually vulnerable to mode collapse and vanishing gradients. The evolutionary generative adversarial network (E-GAN) attempts to alleviate these issues by optimizing the learning…
With the widespread of machine learning models for healthcare applications, there is increased interest in building applications for personalized medicine. Despite the plethora of proposed research for personalized medicine, very few focus…
Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to…
Electronic health records (EHRs) are increasingly recognized as a cost-effective resource for patient recruitment in clinical research. However, how to optimally select a cohort from millions of individuals to answer a scientific question…
Problem: There is a lack of big data for the training of deep learning models in medicine, characterized by the time cost of data collection and privacy concerns. Generative adversarial networks (GANs) offer both the potential to generate…
Electrocardiogram (ECG) data collection during emergency situations is challenging, making ECG data generation an efficient solution for dealing with highly imbalanced ECG training datasets. In this paper, we propose a novel approach for…
When training clinical prediction models from electronic health records (EHRs), a key concern should be a model's ability to sustain performance over time when deployed, even as care practices, database systems, and population demographics…
Recent improvements in Generative Adversarial Neural Networks (GANs) have shown their ability to generate higher quality samples as well as to learn good representations for transfer learning. Most of the representation learning methods…
As a revolutionary generative paradigm of deep learning, generative adversarial networks (GANs) have been widely applied in various fields to synthesize realistic data. However, it is challenging for conventional GANs to synthesize raw…
Electronic Health Records present a valuable modality for driving personalized medicine, where treatment is tailored to fit individual-level differences. For this purpose, many data-driven machine learning and statistical models rely on the…
Acquisition of data in task-specific applications of machine learning like plant disease recognition is a costly endeavor owing to the requirements of professional human diligence and time constraints. In this paper, we present a simple…
Electronic health records (EHRs) contain valuable patient data for health-related prediction tasks, such as disease prediction. Traditional approaches rely on supervised learning methods that require large labeled datasets, which can be…
Analysis of longitudinal Electronic Health Record (EHR) data is an important goal for precision medicine. Difficulty in applying Machine Learning (ML) methods, either predictive or unsupervised, stems in part from the heterogeneity and…
Modern scientific research and applications very often encounter "fragmentary data" which brings big challenges to imputation and prediction. By leveraging the structure of response patterns, we propose a unified and flexible framework…
We study the problem of detecting adverse drug events in electronic healthcare records. The challenge in this work is to aggregate heterogeneous data types involving diagnosis codes, drug codes, as well as lab measurements. An earlier…