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Functional magnetic resonance imaging (fMRI) is a neuroimaging technique known for its ability to capture brain activity non-invasively and at fine spatial resolution (2-3mm). Cortical surface fMRI (cs-fMRI) is a recent development of fMRI…

Applications · Statistics 2023-12-29 Huy Dang , Marzia Cremona , Nicole Lazar , Francesca Chiaromonte

This paper contributes to the multivariate analysis of marked spatio-temporal point process data by introducing different partial point characteristics and extending the spatial dependence graph model formalism. Our approach yields a…

Methodology · Statistics 2020-03-06 Matthias Eckardt , Jonatan A. González , Jorge Mateu

We discuss the Gaussian graphical model (GGM; an undirected network of partial correlation coefficients) and detail its utility as an exploratory data analysis tool. The GGM shows which variables predict one-another, allows for sparse…

Methodology · Statistics 2018-02-09 Sacha Epskamp , Lourens J. Waldorp , René Mõttus , Denny Borsboom

We introduce a probabilistic generative model for disentangling spatio-temporal disease trajectories from series of high-dimensional brain images. The model is based on spatio-temporal matrix factorization, where inference on the sources is…

Machine Learning · Statistics 2019-10-11 Clement Abi Nader , Nicholas Ayache , Philippe Robert , Marco Lorenzi

In the analysis of multivariate spatial and univariate spatio-temporal data, it is commonly recognized that asymmetric dependence may exist, which can be addressed using an asymmetric (matrix or space-time, respectively) covariance function…

Methodology · Statistics 2026-01-29 Drew Yarger

Comprehending the interplay between spatial and temporal characteristics of neural dynamics can contribute to our understanding of information processing in the human brain. Graph neural networks (GNNs) provide a new possibility to…

Neurons and Cognition · Quantitative Biology 2022-04-29 Simon Wein , Alina Schüller , Ana Maria Tomé , Wilhelm M. Malloni , Mark W. Greenlee , Elmar W. Lang

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Multi-subject fMRI studies are challenging due to the high variability of both brain anatomy and functional brain topographies across participants. An effective way of aggregating multi-subject fMRI data is to extract a shared…

Neurons and Cognition · Quantitative Biology 2020-09-08 MohammadReza Ebrahimi , Navona Calarco , Kieran Campbell , Colin Hawco , Aristotle Voineskos , Ashish Khisti

Functional magnetic resonance imaging (fMRI) data contain complex spatiotemporal dynamics, thus researchers have developed approaches that reduce the dimensionality of the signal while extracting relevant and interpretable dynamics. Models…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Eloy Geenjaar , Amrit Kashyap , Noah Lewis , Robyn Miller , Vince Calhoun

This thesis focuses on data that has complex spatio-temporal structure and on probabilistic graphical models that learn the structure in an interpretable and scalable manner. We target two research areas of interest: Gaussian graphical…

Machine Learning · Computer Science 2023-01-18 Yu Wang

Statistical modeling of fMRI data is challenging as the data are both spatially and temporally correlated. Spatially, measurements are taken at thousands of contiguous regions, called voxels, and temporally measurements are taken at…

Computation · Statistics 2017-10-05 Ming Teng , Farouk S. Nathoo , Timothy D. Johnson

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

Applications · Statistics 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

We consider the estimation of large covariance and precision matrices from high-dimensional sub-Gaussian or heavier-tailed observations with slowly decaying temporal dependence. The temporal dependence is allowed to be long-range so with…

Statistics Theory · Mathematics 2019-12-23 Hai Shu , Bin Nan

All neuroimaging modalities have their own strengths and limitations. A current trend is toward interdisciplinary approaches that use multiple imaging methods to overcome limitations of each method in isolation. At the same time…

Methodology · Statistics 2023-03-30 Pratim Guha Niyogi , Martin A. Lindquist , Tapabrata Maiti

Circular data arise in many areas of application. Recently, there has been interest in looking at circular data collected separately over time and over space. Here, we extend some of this work to the spatio-temporal setting, introducing…

Methodology · Statistics 2017-04-18 Gianluca Mastrantonio , Giovanna Jona Lasinio , Alan E. Gelfand

This work proposes an algorithmic framework to learn time-varying graphs from online data. The generality offered by the framework renders it model-independent, i.e., it can be theoretically analyzed in its abstract formulation and then…

Machine Learning · Computer Science 2022-05-25 Alberto Natali , Elvin Isufi , Mario Coutino , Geert Leus

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Gaussian random fields with Mat\'ern covariance functions are popular models in spatial statistics and machine learning. In this work, we develop a spatio-temporal extension of the Gaussian Mat\'ern fields formulated as solutions to a…

Methodology · Statistics 2023-04-06 Finn Lindgren , Haakon Bakka , David Bolin , Elias Krainski , Håvard Rue

Traditional spatio-temporal models for areal data typically begin with spatial structure imposed at the level of random effects and later extend to include temporal dynamics. We propose an alternative hierarchical modeling framework that…

Bayesian spatial modeling provides a flexible framework for whole-brain fMRI analysis by explicitly incorporating spatial dependencies, overcoming the limitations of traditional massive univariate approaches that lead to information waste.…

Methodology · Statistics 2025-11-18 Yuan Zhong , Gang Chen , Paul A. Taylor , Jian Kang
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