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The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Neurons and Cognition · Quantitative Biology 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Brain connectivity can be estimated through a wide number of analyses applied to electroencephalographic (EEG) data. However, substantial heterogeneity in the implementation of connectivity methods exist. Heterogeneity in conceptualization…

Neurons and Cognition · Quantitative Biology 2021-09-01 Aleksandra Miljevic , Neil W. Bailey , Fidel Vila-Rodriguez , Sally E. Herring , Paul B. Fitzgerald

Coherence and phase synchronization between time series corresponding to different spatial locations are usually interpreted as indicators of the connectivity between locations. In neurophysiology, time series of electric neuronal activity…

Methodology · Statistics 2007-07-12 Roberto D. Pascual-Marqui

An important field of research in functional neuroimaging is the discovery of integrated, distributed brain systems and networks, whose different regions need to work in unison for normal functioning. The EEG is a non-invasive technique…

Many different analysis techniques have been developed and applied to EEG recordings that allow one to investigate how different brain areas interact. One particular class of methods, based on the linear parametric representation of…

Neurons and Cognition · Quantitative Biology 2016-11-09 Frederik van de Steen , Luca Faes , Esin Karahan , Jitkomut Songsiri , Pedro Antonio Valdes Sosa , Daniele Marinazzo

Contemporary neuroimaging methods can shed light on the basis of human neural and cognitive specializations, with important implications for neuroscience and medicine. Different MRI acquisitions provide different brain networks at the…

Neurons and Cognition · Quantitative Biology 2016-02-23 C. Alonso-Montes , I. Diez , L. Remaki , I. Escudero , B. Mateos , Y. Rosseel , D. Marinazzo , S. Stramaglia , J. Cortes

This study investigated the dynamic connectivity patterns between EEG and fMRI modalities, contributing to our understanding of brain network interactions. By employing a comprehensive approach that integrated static and dynamic analyses of…

Machine Learning · Computer Science 2024-12-02 Guiran Liu , Binrong Zhu

Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

Methodology · Statistics 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

Statistical significance testing of neural coherence is essential for distinguishing genuine cross-signal coupling from spurious correlations. A widely accepted approach uses surrogate-based inference, where null distributions are generated…

Signal Processing · Electrical Eng. & Systems 2026-05-13 Md Rakibul Mowla , Sukhbinder Kumar , Ariane E. Rhone , Brian J. Dlouhy , Christopher K. Kovach

Independent component analysis (ICA) has proven useful for modeling brain and electroencephalographic (EEG) data. Here, we present a new, generalized method to better capture the dynamics of brain signals than previous ICA algorithms. We…

Quantitative Methods · Quantitative Biology 2007-05-23 Jorn Anemuller , Terrence J. Sejnowski , Scott Makeig

We develop a new statistical method for estimating functional connectivity between neurophysiological signals represented by a multivariate time series. We use partial coherence as the measure of functional connectivity. Partial coherence…

Applications · Statistics 2011-08-17 Mark Fiecas , Hernando Ombao

Studies in recent years have demonstrated that neural organization and structure impact an individual's ability to perform a given task. Specifically, individuals with greater neural efficiency have been shown to outperform those with less…

We present a measure for characterizing statistical relationships between two time sequences. In contrast to commonly used measures like cross-correlations, coherence and mutual information, the proposed measure is non-symmetric and…

chao-dyn · Physics 2009-10-31 J. Arnhold , P. Grassberger , K. Lehnertz , C. E. Elger

EEG signals in emotion recognition absorb special attention owing to their high temporal resolution and their information about what happens in the brain. Different regions of brain work together to process information and meanwhile the…

Signal Processing · Electrical Eng. & Systems 2021-12-24 Ensieh Khazaei , Hoda Mohammadzade

We propose a novel technique to assess functional brain connectivity in EEG/MEG signals. Our method, called Sparsely-Connected Sources Analysis (SCSA), can overcome the problem of volume conduction by modeling neural data innovatively with…

Methodology · Statistics 2010-08-05 Stefan Haufe , Ryota Tomioka , Guido Nolte , Klaus-Robert Mueller , Motoaki Kawanabe

Causal relations among neuronal populations of the brain are studied through the so-called effective connectivity (EC) network. The latter is estimated from EEG or fMRI measurements, by inverting a generative model of the corresponding…

Systems and Control · Computer Science 2018-02-16 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Several scalp EEG functional connectivity studies, mostly clinical, seem to overlook the reference electrode impact. The subsequent interpretation of brain connectivity is thus often biased by the choice a non-neutral reference. This study…

Quantitative Methods · Quantitative Biology 2019-01-25 Federico Chella , Vittorio Pizzella , Filippo Zappasodi , Laura Marzetti

Electroencephalography (EEG) underpins neuroscience, clinical neurophysiology, and brain-computer interfaces (BCIs), yet pronounced inter- and intra-subject variability limits reliability, reproducibility, and translation. This systematic…

Neurons and Cognition · Quantitative Biology 2026-02-03 Xuan-The Tran , Thien-Nhan Vo , Son-Tung Vu , Thoa-Thi Tran , Manh-Dat Nguyen , Thomas Do , Chin-Teng Lin

The extent of intra-individual and inter-individual variability is an important factor in determining the statistical, and hence possibly clinical, significance of observed differences in the EEG. This study investigates the changes in…

Neurons and Cognition · Quantitative Biology 2018-01-08 Sacha Jennifer van Albada , Christopher J. Rennie , Peter A. Robinson

Inferring a binary connectivity graph from resting-state fMRI data for a single subject requires making several methodological choices and assumptions that can significantly affect the results. In this study, we investigate the robustness…

Methodology · Statistics 2025-03-20 Alice Chevaux , Ali Fahkar , Kévin Polisano , Irène Gannaz , Sophie Achard
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