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Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

Machine Learning · Statistics 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

This thesis is dedicated to the statistical analysis of multi-sub ject fMRI data, with the purpose of identifying bain structures involved in certain cognitive or sensori-motor tasks, in a reproducible way across sub jects. To overcome…

Applications · Statistics 2010-05-19 Merlin Keller , Alexis Roche , Marc Lavielle

The wide variety of brain imaging technologies allows us to exploit information inherent to different data modalities. The richness of multimodal datasets may increase predictive power and reveal latent variables that otherwise would have…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Alvaro Ulloa , Sergey Plis , Vince Calhoun

Multireference alignment (MRA) problem is to estimate an underlying signal from a large number of noisy circularly-shifted observations. The existing methods are always proposed under the hypothesis of a single Gaussian noise. However, the…

Optimization and Control · Mathematics 2021-07-23 Cuicui Zhao , Jun Liu , Xinqi Gong

Recent advances in multi-modal large language models (MLLMs) have opened new possibilities for unified modeling of speech, text, images, and other modalities. Building on our prior work, this paper examines the conditions and model…

Sound · Computer Science 2025-07-28 Yiwen Guan , Viet Anh Trinh , Vivek Voleti , Jacob Whitehill

The acquisition of MRI images offers a trade-off in terms of acquisition time, spatial/temporal resolution and signal-to-noise ratio (SNR). Thus, for instance, increasing the time efficiency of MRI often comes at the expense of reduced SNR.…

Computer Vision and Pattern Recognition · Computer Science 2011-10-28 Sudipto Dolui , Alan Kuurstra , Iván C. Salgado Patarroyo , Oleg V. Michailovich

Purpose: To develop neural network (NN)-based quantitative MRI parameter estimators with minimal bias and a variance close to the Cram\'er-Rao bound. Theory and Methods: We generalize the mean squared error loss to control the bias and…

Medical Physics · Physics 2024-05-07 Andrew Mao , Sebastian Flassbeck , Jakob Assländer

Similarity analysis is one of the crucial steps in most fMRI studies. Representational Similarity Analysis (RSA) can measure similarities of neural signatures generated by different cognitive states. This paper develops Deep…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Muhammad Yousefnezhad , Jeffrey Sawalha , Alessandro Selvitella , Daoqiang Zhang

Purpose: This work aims at developing a generalizable MRI reconstruction model in the meta-learning framework. The standard benchmarks in meta-learning are challenged by learning on diverse task distributions. The proposed network learns…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Wanyu Bian , Yunmei Chen , Xiaojing Ye , Qingchao Zhang

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

Applications · Statistics 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Detecting shared neural activity from functional magnetic resonance imaging (fMRI) across individuals exposed to the same stimulus can reveal synchronous brain responses, functional roles of regions, and potential clinical biomarkers.…

Applications · Statistics 2026-04-24 Spencer Wadsworth , Nabin Koirala , Nicole Landi , Ofer Harel

The multi-reference alignment (MRA) problem entails estimating an image from multiple noisy and rotated copies of itself. If the noise level is low, one can reconstruct the image by estimating the missing rotations, aligning the images, and…

Signal Processing · Electrical Eng. & Systems 2022-06-17 Noam Janco , Tamir Bendory

Multimodal learning has been lacking principled ways of combining information from different modalities and learning a low-dimensional manifold of meaningful representations. We study multimodal learning and sensor fusion from a latent…

Machine Learning · Computer Science 2019-04-24 Lijiang Guo

Speech recognition system performance degrades in noisy environments. If the acoustic models are built using features of clean utterances, the features of a noisy test utterance would be acoustically mismatched with the trained model. This…

Computation and Language · Computer Science 2015-07-16 D. S. Pavan Kumar

We develop a new method to fit the multivariate response linear regression model that exploits a parametric link between the regression coefficient matrix and the error covariance matrix. Specifically, we assume that the correlations…

Methodology · Statistics 2021-12-09 Aaron J. Molstad , Guangwei Weng , Charles R. Doss , Adam J. Rothman

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

Enhancing noisy speech is an important task to restore its quality and to improve its intelligibility. In traditional non-machine-learning (ML) based approaches the parameters required for noise reduction are estimated blindly from the…

Sound · Computer Science 2018-01-16 Robert Rehr , Timo Gerkmann

We propose a calibrated multivariate regression method named CMR for fitting high dimensional multivariate regression models. Compared with existing methods, CMR calibrates regularization for each regression task with respect to its noise…

Machine Learning · Statistics 2017-06-06 Han Liu , Lie Wang , Tuo Zhao

Functional magnetic resonance imaging (fMRI) is a powerful tool for investigating human brain function. However, the high cost of data acquisition and the inherent subjectivity of psychiatric rating scales often lead to datasets with small…

Machine Learning · Computer Science 2026-05-29 Jiyao Wang , Peiyu Duan , Nicha C. Dvornek , Lawrence H. Staib , Denis Sukhodolsky , Pamela Ventola , James S. Duncan

Functional Magnetic Resonance Imaging (fMRI) is a neuroimaging technique with pivotal importance due to its scientific and clinical applications. As with any widely used imaging modality, there is a need to ensure the quality of the same,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-29 David Calhas , Rui Henriques