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Since decades, many techniques have been developed for curing cancer. Here, an effort has been made to cure tumor by inserting a cryoprobe into the target region which is connected to a cryogenic mechanism. This technique is presently used…

Medical Physics · Physics 2022-12-23 G Sai Krishna , Anup Paul

Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-04 Barbara Wirthl , Paolo Decuzzi , Bernhard A. Schrefler , Wolfgang A. Wall

During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of…

Medical Physics · Physics 2020-07-29 Abhijit Paul , Anup Paul

Magnetic hyperthermia is a new type of cancer treatment designed for overcoming resistance to chemotherapy during the treatment of solid, inaccessible human tumors. The main challenge of this technology is increasing the local tumoral…

Tissues and Organs · Quantitative Biology 2016-11-09 Beatriz Sanz , M. Pilar Calatayud , Teobaldo E. Torres , Mónica L. Fanarraga , M. Ricardo Ibarra , Gerardo F. Goya

We report a model for hyperthermia therapies based on heat diffusion in a biological tissue containing a topological defect. Biological tissues behave like active liquid crystals with the presence of topological defects which are likely to…

Statistical Mechanics · Physics 2024-10-02 Andy Manapany , Loriane Didier , Leïla Moueddene , Bertrand Berche , Sébastien Fumeron

During thermal heating surgical procedures such as electrosurgery, thermal ablative treatment and hyperthermia, soft tissue deformation due to tool-tissue interaction and patients' motion can affect the distribution of induced thermal…

Computational Engineering, Finance, and Science · Computer Science 2022-01-03 Jinao Zhang , Sunita Chauhan

Cryoablation is a minimally invasive and efficient therapy option for liver cancer. Liquid nitrogen was used to kill the unwanted cells via freezing. One of the challenges of cryosurgery is to destroy the complete tumor without damaging the…

Medical Physics · Physics 2023-09-19 Gangadhara Boregowda , Panchatcharam Mariappan

Hyperthermia has been in use for many years; as a potential alternative modality for cancer treatment. In this paper, an experimental investigation of microwave assisted thermal heating (MWATH) of tissue phantom using a domestic microwave…

Medical Physics · Physics 2020-06-25 Dhiraj Kumar , Purbarun Dhar , Anup Paul

Amorphization of silicon is crucial to applications in photonics, microelectronics and solar cell technologies. Ultrafast lasers have been used to generate amorphous silicon from crystalline silicon using rapid nonthermal melting and…

Real-time analysis of bio-heat transfer is very beneficial in improving clinical outcomes of hyperthermia and thermal ablative treatments but challenging to achieve due to large computational costs. This paper presents a fast numerical…

Computational Engineering, Finance, and Science · Computer Science 2021-12-30 Jinao Zhang , Sunita Chauhan

A theoretical model is developed that can accurately analyze the effects of thermal fluctuations in antiferromagnetic (AFM) nano-particles. The approach is based on Fourier series representation of the random effective field with cut-off…

Mesoscale and Nanoscale Physics · Physics 2019-07-26 Yuriy G. Semenov , Xiniy Xu , Ki Wook Kim

Enhanced geothermal systems (EGS) involve strongly coupled, advection-dominated flow and heat transfer in fractured porous media. Conventional models typically assume local thermal equilibrium with a single effective fluid temperature or,…

Numerical Analysis · Mathematics 2026-04-23 Yi-Yung Yang , Sanghyun Lee , Dmitri Kuzmin

In this study, we conduct a study on magnetic hyperthermia treatment when a vessel is located near the tumor. The holistic framework is established to solve the process of tumor treatment. The interstitial tissue fluid, MNP distribution,…

If confocal microscopy is an ubiquitous tool in life science, its applications in chemistry and materials science are still, in comparison, very limited. Of particular interest in these domains is the use of confocal microscopy to…

Soft Condensed Matter · Physics 2017-12-25 Dmytro Dedovets , Cécile Monteux , Sylvain Deville

Photoinduced hyperthermia is a cancer therapy technique that induces death to cancerous cells via heat generated by plasmonic nanoparticles. While previous studies have shown that some nanoparticles can be effective at killing cancer cells…

Electrospinning is historically related to tissue engineering due to its ability to produce nano-/microscale fibrous materials with mechanical and functional properties that are extremely similar to those of the extracellular matrix of…

In cryo-electron microscopy, accurate particle localization and classification are imperative. Recent deep learning solutions, though successful, require extensive training data sets. The protracted generation time of physics-based models,…

Machine Learning · Computer Science 2025-02-20 Pavol Harar , Lukas Herrmann , Philipp Grohs , David Haselbach

A non-isothermal phase field model that captures both displacive and diffusive phase transformations in a unified framework is presented. The model is developed in a formal thermodynamic setting, which provides guidance on admissible…

Materials Science · Physics 2011-12-02 Mirko Maraldi , Garth N. Wells , Luisa Molari

In the U.S., approximately 17 patients die each day awaiting an organ transplant, a crisis driven by the inability to store organs long-term via methods like cryopreservation. A primary failure mechanism is the severe thermo-mechanical…

Soft Condensed Matter · Physics 2025-11-20 Ali Saeedi , Ram Devireddy , Mrityunjay Kothari

Charge transfer is a fundamental process that underlies a multitude of phenomena in chemistry and biology. Recent advances in observing and manipulating charge and heat transport at the nanoscale, and recently developed techniques for…

Mesoscale and Nanoscale Physics · Physics 2016-07-26 Galen T. Craven , Abraham Nitzan
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