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We introduce an efficient and robust method to compute alchemical free energy differences, resulting from the application of multiple walker Adaptive Biasing Force (ABF) in conjunction with strongly damped Langevin $\lambda$-dynamics.…

Recent work in scalable approximate Gaussian process regression has discussed a bias-variance-computation trade-off when estimating the log marginal likelihood. We suggest a method that adaptively selects the amount of computation to use…

Machine Learning · Statistics 2021-09-21 David R. Burt , Artem Artemev , Mark van der Wilk

We present a posteriori error estimates for a recently developed atomistic/continuum coupling method, the Consistent Energy-Based QC Coupling method. The error estimate of the deformation gradient combines a residual estimate and an a…

Numerical Analysis · Mathematics 2011-12-26 Hao Wang

The implementation and validation of the adaptive buffered force QM/MM method in two popular packages, CP2K and AMBER are presented. The implementations build on the existing QM/MM functionality in each code, extending it to allow for…

In this paper, we propose a proximal stochasitc gradient algorithm (PSGA) for solving composite optimization problems by incorporating variance reduction techniques and an adaptive step-size strategy. In the PSGA method, the objective…

Optimization and Control · Mathematics 2026-04-06 Changjie Fang , Hao Yang , Shenglan Chen

This work focuses on convergence analysis of the projected gradient method for solving constrained convex minimization problem in Hilbert spaces. We show that the sequence of points generated by the method employing the Armijo linesearch…

Optimization and Control · Mathematics 2015-08-10 Jose Yunier Bello Cruz , Welington de Oliveira

We introduce what we call the second-order Boltzmann-Gibbs principle, which allows to replace local functionals of a conservative, one-dimensional stochastic process by a possibly nonlinear function of the conserved quantity. This…

Probability · Mathematics 2015-06-17 Patricia Gonçalves , Milton Jara

The computational modelling of reactions is simple in theory but can be quite tricky in practice. This article aims at the purpose of providing an assistance to a proper way of describing reactions theoretically and provides rough…

Chemical Physics · Physics 2017-02-14 Arnim Hellweg , Frank Eckert

This paper develops new variance-reduction techniques for the forward-reflected-backward splitting (FRBS) method to solve a class of possibly nonmonotone stochastic composite inclusions. Unlike unbiased estimators such as mini-batching,…

Machine Learning · Computer Science 2026-03-17 Quoc Tran-Dinh , Nghia Nguyen-Trung

The stochastic gradient descent has been widely used for solving composite optimization problems in big data analyses. Many algorithms and convergence properties have been developed. The composite functions were convex primarily and…

Machine Learning · Statistics 2020-03-03 Takayuki Kawashima , Hironori Fujisawa

Free energy calculations based on atomistic Hamiltonians provide microscopic insight into the thermodynamic driving forces of biophysical or condensed matter systems. Many approaches use intermediate Hamiltonians interpolating between the…

Computational Physics · Physics 2021-12-08 Martin Reinhardt , Helmut Grubmüller

We propose a new method to obtain kinetic properties of infrequent events from molecular dynamics simulation. The procedure employs a recently introduced variational approach [Valsson and Parrinello, Phys. Rev. Lett. 113, 090601 (2014)] to…

Statistical Mechanics · Physics 2015-08-19 James McCarty , Omar Valsson , Pratyush Tiwary , Michele Parrinello

We revisit force evaluation methodologies on rigid solid particles suspended in a viscous fluid and simulated via lattice Boltzmann method (LBM). We point out the non-commutativity of streaming and collision operators in the force…

Fluid Dynamics · Physics 2022-10-20 Shaurya Kaushal , Sauro Succi , Santosh Ansumali

In this paper, we present an adaptive gradient descent method for geodesically convex optimization on a Riemannian manifold with nonnegative sectional curvature. The method automatically adapts to the local geometry of the function and does…

Optimization and Control · Mathematics 2025-09-16 Aban Ansari-Önnestam , Yura Malitsky

We consider a nonlinear convex stochastic homogenization problem, in a stationary setting. In practice, the deterministic homogenized energy density can only be approximated by a random apparent energy density, obtained by solving the…

Numerical Analysis · Mathematics 2013-02-04 Frederic Legoll , William Minvielle

Adaptive Gradient Descent with Energy (AEGD) is a variant of gradient descent (GD) designed to mitigate step-size sensitivity through an energy-based formulation. AEGD is notable for its unconditional energy stability, which guarantees…

Optimization and Control · Mathematics 2025-12-16 Lin Feng , Hailiang Liu

This paper presents a novel stochastic gradient descent algorithm for constrained optimization. The proposed algorithm randomly samples constraints and components of the finite sum objective function and relies on a relaxed logarithmic…

Optimization and Control · Mathematics 2025-05-13 Naum Dimitrieski , Jing Cao , Christian Ebenbauer

Restricted Boltzmann machines (RBMs) are a powerful class of generative models, but their training requires computing a gradient that, unlike supervised backpropagation on typical loss functions, is notoriously difficult even to…

Machine Learning · Computer Science 2020-11-03 Haik Manukian , Yan Ru Pei , Sean R. B. Bearden , Massimiliano Di Ventra

Bayesian methods which utilize Bayes' theorem to update the knowledge of desired parameters after each measurement, are used in a wide range of quantum science. For various applications in quantum science, efficiently and accurately…

Quantum Physics · Physics 2021-07-02 Chengyin Han , Jiahao Huang , Xunda Jiang , Ruihuan Fang , Yuxiang Qiu , Bo Lu , Chaohong Lee

We develop a new method for proving hypocoercivity for a large class of linear kinetic equations with only one conservation law. Local mass conservation is assumed at the level of the collision kernel, while transport involves a confining…

Analysis of PDEs · Mathematics 2010-05-11 Jean Dolbeault , Clément Mouhot , Christian Schmeiser