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Normal networks are an important class of phylogenetic networks that have compelling mathematical properties which align with intuition about inference from genetic data. While tools enabling widespread use of phylogenetic networks in the…

Combinatorics · Mathematics 2025-12-16 Andrew Francis , Charles Semple

This paper focuses on spectral graph convolutional neural networks (ConvNets), where filters are defined as elementwise multiplication in the frequency domain of a graph. In machine learning settings where the dataset consists of signals…

Machine Learning · Computer Science 2021-06-15 Ron Levie , Wei Huang , Lorenzo Bucci , Michael M. Bronstein , Gitta Kutyniok

Three-way dissimilarities are a generalization of (two-way) dissimilarities which can be used to indicate the lack of homogeneity or resemblance between any three objects. Such maps have applications in cluster analysis, and have been used…

Combinatorics · Mathematics 2017-10-19 Katharina T. Huber , Vincent Moulton , Guillaume E. Scholz

Graphs are interesting structures: extremely useful to depict real-life problems, extremely easy to understand given a sketch, extremely complicated to represent formally, extremely complicated to compare. Phylogeny is the study of the…

Data Structures and Algorithms · Computer Science 2019-01-18 Bernardo Lopo Tavares

Reticulate evolution can be modelled using phylogenetic networks. Tree-based networks, which are one of the more general classes of phylogenetic networks, have recently gained eminence for its ability to represent evolutionary histories…

Populations and Evolution · Quantitative Biology 2024-07-15 Joan Carles Pons , Pau Vives López , Yukihiro Murakami , Leo Van Iersel

Phylogenetic networks generalize phylogenetic trees by allowing the modelization of events of reticulate evolution. Among the different kinds of phylogenetic networks that have been proposed in the literature, the subclass of binary…

Data Structures and Algorithms · Computer Science 2020-07-01 Gabriel Cardona , Joan Carles Pons , Celine Scornavacca

Genome-scale orthology assignments are usually based on reciprocal best matches. In the absence of horizontal gene transfer (HGT), every pair of orthologs forms a reciprocal best match. Incorrect orthology assignments therefore are always…

Populations and Evolution · Quantitative Biology 2020-11-30 David Schaller , Manuela Geiß , Peter F. Stadler , Marc Hellmuth

Rooted acyclic graphs appear naturally when the phylogenetic relationship of a set $X$ of taxa involves not only speciations but also recombination, horizontal transfer, or hybridization, that cannot be captured by trees. A variety of…

Populations and Evolution · Quantitative Biology 2022-04-29 Marc Hellmuth , David Schaller , Peter F. Stadler

We introduce a simple algorithm for reconstructing phylogenies from multiple gene trees in the presence of incomplete lineage sorting, that is, when the topology of the gene trees may differ from that of the species tree. We show that our…

Populations and Evolution · Quantitative Biology 2011-09-30 Elchanan Mossel , Sebastien Roch

A rigorous methodology is proposed to study cell division data consisting in several observed genealogical trees of possibly different shapes. The procedure takes into account missing observations, data from different trees, as well as the…

Applications · Statistics 2013-04-15 Benoîte de Saporta , Anne Gégout Petit , Laurence Marsalle

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

A graph $G$ is said to be a `set graph' if it admits an acyclic orientation that is also `extensional', in the sense that the out-neighborhoods of its vertices are pairwise distinct. Equivalently, a set graph is the underlying graph of the…

Discrete Mathematics · Computer Science 2015-03-20 Martin Milanič , Romeo Rizzi , Alexandru I. Tomescu

The need for structures capable of accommodating complex evolutionary signals such as those found in, for example, wheat has fueled research into phylogenetic networks. Such structures generalize the standard phylogenetic tree model by also…

Combinatorics · Mathematics 2015-11-30 Philippe Gambette , Katharina T. Huber , Guillaume E. Scholz

Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species that evolved from a common ancestor. When phylogenetic trees…

Populations and Evolution · Quantitative Biology 2009-10-19 Leo van Iersel , Steven Kelk , Regula Rupp , Daniel Huson

Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history and numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains…

Populations and Evolution · Quantitative Biology 2024-03-26 Mingyang Zhou , Zichao Yan , Elliot Layne , Nikolay Malkin , Dinghuai Zhang , Moksh Jain , Mathieu Blanchette , Yoshua Bengio

Let $G$ be a graph on $n\geq 3$ vertices. A graph $G$ is almost distance-hereditary if each connected induced subgraph $H$ of $G$ has the property $d_{H}(x,y)\leq d_{G}(x,y)+1$ for any pair of vertices $x,y\in V(H)$. A graph $G$ is called…

Combinatorics · Mathematics 2016-06-13 Bing Chen , Bo Ning

For a pair consisting of a gene tree and a species tree, the ancestral configurations at an internal node of the species tree are the distinct sets of gene lineages that can be present at that node. Ancestral configurations appear in…

Combinatorics · Mathematics 2020-06-17 Filippo Disanto , Michael Fuchs , Ariel R. Paningbatan , Noah A. Rosenberg

Treewidth is a parameter that emerged from the study of minor closed classes of graphs (i.e. classes closed under vertex and edge deletion, and edge contraction). It in some sense describes the global structure of a graph. Roughly, a graph…

Combinatorics · Mathematics 2022-02-02 Tara Abrishami , Maria Chudnovsky , Kristina Vušković

In evolutionary biology, genetic sequences carry with them a trace of the underlying tree that describes their evolution from a common ancestral sequence. The question of how many sequence sites are required to recover this evolutionary…

Populations and Evolution · Quantitative Biology 2008-06-17 Mareike Fischer , Mike Steel

Phylogenetic trees play a key role in the reconstruction of evolutionary relationships. Typically, they are derived from aligned sequence data (like DNA, RNA, or proteins) by using optimization criteria like, e.g., maximum parsimony (MP).…

Populations and Evolution · Quantitative Biology 2025-06-11 Mirko Wilde , Mareike Fischer