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Lidar SLAM plays a significant role in mobile robot navigation and high-definition map construction. However, existing methods often face a trade-off between localization accuracy and system robustness in scenarios with a high proportion of…

Robotics · Computer Science 2025-12-02 Yongxin Shao , Aihong Tan , Binrui Wang , Yinlian Jin , Licong Guan , Peng Liao

Motif discovery is one of the most challenging problems in bioinformatics today. DNA sequence motifs are becoming increasingly important in analysis of gene regulation. Motifs are short, recurring patterns in DNA that have a biological…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-05-05 Umang Vipul

A major challenge in next-generation genome sequencing (NGS) is to assemble massive overlapping short reads that are randomly sampled from DNA fragments. To complete assembling, one needs to finish a fundamental task in many leading…

Genomics · Quantitative Biology 2015-05-26 Yang Li , XifengYan

Genome assembly from the high-throughput sequencing (HTS) reads is a fundamental yet challenging computational problem. An intrinsic challenge is the uncertainty caused by the widespread repetitive elements. Here we get around the…

Genomics · Quantitative Biology 2016-09-13 Anqi Wang , Zheng Li , Zhanyu Wang , Lei M. Li

Motivation: Deep learning architectures have recently demonstrated their power in predicting DNA- and RNA-binding specificities. Existing methods fall into three classes: Some are based on Convolutional Neural Networks (CNNs), others use…

Machine Learning · Computer Science 2019-01-31 Ameni Trabelsi , Mohamed Chaabane , Asa Ben Hur

Minimizers and convolutional neural networks (CNNs) are two quite distinct popular techniques that have both been employed to analyze categorical biological sequences. At face value, the methods seem entirely dissimilar. Minimizers use…

Machine Learning · Computer Science 2024-01-29 Yun William Yu

SLAM (Simultaneous Localisation and Mapping) is a crucial component for robotic systems, providing a map of an environment, the current location and previous trajectory of a robot. While 3D LiDAR SLAM has received notable improvements in…

Robotics · Computer Science 2025-04-29 Leon Davies , Baihua Li , Mohamad Saada , Simon Sølvsten , Qinggang Meng

Gravitational-wave detection strategies are based on a signal analysis technique known as matched filtering. Despite the success of matched filtering, due to its computational cost, there has been recent interest in developing deep…

General Relativity and Quantum Cosmology · Physics 2022-11-03 Dwyer S. Deighan , Scott E. Field , Collin D. Capano , Gaurav Khanna

Motivation: Predicting the secondary structure of an RNA sequence is useful in many applications. Existing algorithms (based on dynamic programming) suffer from a major limitation: their runtimes scale cubically with the RNA length, and…

Biomolecules · Quantitative Biology 2020-01-14 Liang Huang , He Zhang , Dezhong Deng , Kai Zhao , Kaibo Liu , David A. Hendrix , David H. Mathews

In the past several years, the problem of genome assembly has received considerable attention from both biologists and computer scientists. An important component of current assembly methods is the scaffolding process. This process involves…

Genomics · Quantitative Biology 2013-07-03 Karl R. B. Schmitt , Aleksey V. Zimin , Guillaume Marcaçs , James A. Yorke , Michelle Girvan

In the current deep learning based recommendation system, the embedding method is generally employed to complete the conversion from the high-dimensional sparse feature vector to the low-dimensional dense feature vector. However, as the…

Information Retrieval · Computer Science 2021-08-10 Huimin Zhou , Qing Li , Yong Jiang , Rongwei Yang , Zhuyun Qi

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

Cryptographic algorithms such as AES-128 and SHA-256 are fundamental to ensuring data security and integrity. Although these algorithms are computationally efficient, their performance is often constrained by the processor-centric…

Cryptography and Security · Computer Science 2026-05-20 Nicola Barcarolo , Brahmaiah Gandham , Mohammad Sadrosadati , Roberto Passerone , Onur Mutlu , Flavio Vella

Metagenomic studies have increasingly utilized sequencing technologies in order to analyze DNA fragments found in environmental samples.One important step in this analysis is the taxonomic classification of the DNA fragments. Conventional…

Genomics · Quantitative Biology 2020-02-11 Andreas Georgiou , Vincent Fortuin , Harun Mustafa , Gunnar Rätsch

The second-order training methods can converge much faster than first-order optimizers in DNN training. This is because the second-order training utilizes the inversion of the second-order information (SOI) matrix to find a more accurate…

Hardware Architecture · Computer Science 2022-10-28 Yilong Zhao , Li Jiang , Mingyu Gao , Naifeng Jing , Chengyang Gu , Qidong Tang , Fangxin Liu , Tao Yang , Xiaoyao Liang

Compute-in-memory (CiM) is a promising approach to improving the computing speed and energy efficiency in dataintensive applications. Beyond existing CiM techniques of bitwise logic-in-memory operations and dot product operations, this…

Hardware Architecture · Computer Science 2023-01-03 Yiming Chen , Yushen Fu , Mingyen Lee , Sumitha George , Yongpan Liu , Vijaykrishnan Narayanan , Huazhong Yang , Xueqing Li

The process of DNA-based data storage (DNA storage for short) can be mathematically modelled as a communication channel, termed DNA storage channel, whose inputs and outputs are sets of unordered sequences. To design error correcting codes…

Information Theory · Computer Science 2020-06-11 Wentu Song , Kui Cai , Kees A. Schouhamer Immink

Deep sequencing has enabled the investigation of a wide range of environmental microbial ecosystems, but the high memory requirements for {\em de novo} assembly of short-read shotgun sequencing data from these complex populations are an…

Genomics · Quantitative Biology 2015-06-03 Jason Pell , Arend Hintze , Rosangela Canino-Koning , Adina Howe , James M. Tiedje , C. Titus Brown

Vision Transformer (ViT) has been widely used in computer vision tasks with excellent results by providing representations for a whole image or image patches. However, ViT lacks detailed localized image representations at arbitrary…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Zeping Liu , Ni Lao , Zhangyu Wang , Junfeng Jiao , Gengchen Mai

In image-based camera localization systems, information about the environment is usually stored in some representation, which can be referred to as a map. Conventionally, most maps are built upon hand-crafted features. Recently, neural…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Mingpan Guo , Stefan Matthes , Jiaojiao Ye , Hao Shen