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Producing subnational estimates of the under-five mortality rate (U5MR) is a vital goal for the United Nations to reduce inequalities in mortality and well-being across the globe. There is a great disparity in U5MR between high-income and…

Applications · Statistics 2023-09-06 Connor Gascoigne , Theresa Smith , John Paige , Jon Wakefield

The under-5 mortality rate (U5MR), a critical health indicator, is typically estimated from household surveys in lower and middle income countries. Spatio-temporal disaggregation of household survey data can lead to highly variable…

Methodology · Statistics 2023-09-06 Serge Aleshin-Guendel , Jon Wakefield

Estimates of the under-five mortality rate (U5MR) are used to track progress in reducing child mortality and to evaluate countries' performance related to Millennium Development Goal 4. However, for the great majority of developing…

Applications · Statistics 2015-01-20 Leontine Alkema , Jin Rou New

Accurate and precise estimates of the under-5 mortality rate (U5MR) are an important health summary for countries. However, full survival curves allow us to better understand the pattern of mortality in children under five. Modern…

Methodology · Statistics 2024-08-19 Taylor Okonek , Katherine Wilson , Jon Wakefield

Many people living in low- and middle-income countries are not covered by civil registration and vital statistics systems. Consequently, a wide variety of other types of data, including many household sample surveys, are used to estimate…

In recent years, much of the focus in monitoring child mortality has been on assessing changes in the under-five mortality rate (U5MR). However, as the U5MR decreases, the share of neonatal deaths (within the first month) tends to increase,…

Applications · Statistics 2021-01-14 Monica Alexander , Leontine Alkema

Reliable mortality estimates at the subnational level are essential in the study of health inequalities within a country. One of the difficulties in producing such estimates is the presence of small populations, where the stochastic…

Applications · Statistics 2017-12-05 Monica Alexander , Emilio Zagheni , Magali Barbieri

Improving health in the most disadvantaged populations requires reliable estimates of health and demographic indicators to inform policy and interventions. Low- and middle-income countries with the largest burden of disease and disability…

Methodology · Statistics 2025-11-21 Austin E Schumacher , Jon Wakefield

Child mortality is an important population health indicator. However, many countries lack high-quality vital registration to measure child mortality rates precisely and reliably over time. Research endeavors such as those by the United…

Applications · Statistics 2026-01-29 Katherine R Paulson , Taylor Okonek , Jon Wakefield

Accurate estimates of subnational populations are important for policy formulation and monitoring population health indicators. For example, estimates of the number of women of reproductive age are important to understand the population at…

Applications · Statistics 2021-02-16 Monica Alexander , Leontine Alkema

The maternal mortality ratio (MMR) is defined as the number of maternal deaths in a population per 100,000 live births. Country-specific MMR estimates are published on a regular basis by the United Nations Maternal Mortality Estimation…

In low- and middle-income countries, household surveys are the most reliable data source to examine health and demographic indicators at the subnational level, an exercise in small area estimation. Model-based unit-level models are favored…

Methodology · Statistics 2022-09-23 Yunhan Wu , Jon Wakefield

The United Nations' Sustainable Development Goal 3.2 aims to reduce under-5 child mortality to 25 deaths per 1,000 live births by 2030. Child mortality tends to be concentrated in developing regions where much of the information needed to…

Applications · Statistics 2018-10-10 Katie Wilson , Jon Wakefield

The need for rigorous and timely health and demographic summaries has provided the impetus for an explosion in geographic studies, with a common approach being the production of pixel-level maps, particularly in low and middle income…

Methodology · Statistics 2019-10-16 John Paige , Geir-Arne Fuglstad , Andrea Riebler , Jon Wakefield

Understanding patterns in mortality across subpopulations is essential for local health policy decision making. One of the key challenges of subnational mortality rate estimation is the presence of small populations and zero or near zero…

Applications · Statistics 2025-12-16 Ameer Dharamshi , Monica Alexander , Celeste Winant , Magali Barbieri

This work introduces a Bayesian smoothing approach for the joint graduation of mortality rates across multiple populations. In particular, dynamical linear models are used to induce smoothness across ages through structured dependence,…

Model-based disease mapping remains a fundamental policy-informing tool in the fields of public health and disease surveillance. Hierarchical Bayesian models have emerged as the state-of-the-art approach for disease mapping since they are…

Machine Learning · Computer Science 2023-07-18 Elizaveta Semenova , Swapnil Mishra , Samir Bhatt , Seth Flaxman , H Juliette T Unwin

Education is a key driver of social and economic mobility, yet disparities in attainment persist, particularly in low- and middle-income countries (LMICs). Existing indicators, such as mean years of schooling for adults aged 25 and older…

Methodology · Statistics 2025-02-13 Yunhan Wu , Ameer Dharamshi , Jon Wakefield

Accurate mortality modeling is central to actuarial science and public health, especially as mental health emerges as a significant factor in population outcomes. This paper develops and applies a Bayesian hierarchical model to analyze U.S.…

In low- and middle-income countries (LMICs), accurate estimates of subnational health and demographic indicators are critical for guiding policy and identifying disparities. Many indicators of interest are proportions of binary outcomes and…

Applications · Statistics 2025-06-23 Jon Wakefield , Peter A. Gao , Geir-Arne Fuglstad , Zehang Richard Li
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