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Decrypting intelligence from the human brain construct is vital in the detection of particular neurological disorders. Recently, functional brain connectomes have been used successfully to predict behavioral scores. However,…

Neurons and Cognition · Quantitative Biology 2022-09-28 Imen Jegham , Islem Rekik

The dynamic characteristics of functional network connectivity have been widely acknowledged and studied. Both shared and unique information has been shown to be present in the connectomes. However, very little has been known about whether…

Neurons and Cognition · Quantitative Biology 2020-06-18 Biao Cai , Gemeng Zhang , Aiying Zhang , Li Xiao , Wenxing Hu , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu-Ping Wang

This paper introduces a new probabilistic architecture called Sum-Product Graphical Model (SPGM). SPGMs combine traits from Sum-Product Networks (SPNs) and Graphical Models (GMs): Like SPNs, SPGMs always enable tractable inference using a…

Machine Learning · Statistics 2017-08-23 Mattia Desana , Christoph Schnörr

Random graphs, where the connections between nodes are considered random variables, have wide applicability in the social sciences. Exponential-family Random Graph Models (ERGM) have shown themselves to be a useful class of models for…

Methodology · Statistics 2012-08-02 Ian Fellows , Mark S. Handcock

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

We introduce a new approach to functional causal modeling from observational data, called Causal Generative Neural Networks (CGNN). CGNN leverages the power of neural networks to learn a generative model of the joint distribution of the…

The characterisation of the brain as a "connectome", in which the connections are represented by correlational values across timeseries and as summary measures derived from graph theory analyses, has been very popular in the last years.…

Machine Learning · Computer Science 2020-03-13 Tiago Azevedo , Luca Passamonti , Pietro Liò , Nicola Toschi

For constructing neuronal network models computational neuroscientists have access to wide-ranging anatomical data that nevertheless tend to cover only a fraction of the parameters to be determined. Finding and interpreting the most…

In Graph Neural Networks (GNNs), the graph structure is incorporated into the learning of node representations. This complex structure makes explaining GNNs' predictions become much more challenging. In this paper, we propose PGM-Explainer,…

Machine Learning · Computer Science 2020-10-13 Minh N. Vu , My T. Thai

Identifying the spatio-temporal network structure of brain activity from multi-neuronal data streams is one of the biggest challenges in neuroscience. Repeating patterns of precisely timed activity across a group of neurons is potentially…

Neurons and Cognition · Quantitative Biology 2009-03-03 Casey Diekman , Kohinoor Dasgupta , Vijay Nair , P. S. Sastry , K. P. Unnikrishnan

The study of functional brain connectivity (FC) is important for understanding the underlying mechanisms of many psychiatric disorders. Many recent analyses adopt graph convolutional networks, to study non-linear interactions between…

Neurons and Cognition · Quantitative Biology 2021-09-08 Simon Dahan , Logan Z. J. Williams , Daniel Rueckert , Emma C. Robinson

Neural network models in neuroscience allow one to study how the connections between neurons shape the activity of neural circuits in the brain. In this chapter, we study Combinatorial Threshold-Linear Networks (CTLNs) in order to…

Neurons and Cognition · Quantitative Biology 2018-04-05 Katherine Morrison , Carina Curto

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

Neurons and Cognition · Quantitative Biology 2020-10-06 Richard Betzel

Large scale neural recordings have established that the transformation of sensory stimuli into motor outputs relies on low-dimensional dynamics at the population level, while individual neurons exhibit complex selectivity. Understanding how…

Neurons and Cognition · Quantitative Biology 2018-08-29 Francesca Mastrogiuseppe , Srdjan Ostojic

The function and dynamics of the cortex are fundamentally shaped by the specific wiring configurations of its constituent axonal fibers, also known as the connectome. However, many dynamical properties of macroscale cortical activity are…

Neurons and Cognition · Quantitative Biology 2025-06-25 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

The combination of new recording techniques in neuroscience and powerful inference methods recently held the promise to recover useful effective models, at the single neuron or network level, directly from observed data. The value of a…

Neurons and Cognition · Quantitative Biology 2018-04-09 Cristiano Capone , Guido Gigante , Paolo Del Giudice

In the study of biological networks, one of the major challenges is to understand the relationships between network structure and dynamics. In this paper, we model in vitro cortical neuronal cultures as stochastic dynamical systems and…

Neurons and Cognition · Quantitative Biology 2022-05-04 Chumin Sun , K. C. Lin , C. Y. Yeung , Emily S. C. Ching , Yu-Ting Huang , Pik-Yin Lai , C. K. Chan

We propose the Financial Connectome, a new scientific discipline that models financial markets through the lens of brain functional architecture. Inspired by the foundational work of group independent component analysis (groupICA) in…

Computational Finance · Quantitative Finance 2026-03-24 Yuda Bi , Vince D Calhoun

Understanding the relation between cortical neuronal network structure and neuronal activity is a fundamental unresolved question in neuroscience, with implications to our understanding of the mechanism by which neuronal networks evolve…

Generalized linear models are one of the most efficient paradigms for predicting the correlated stochastic activity of neuronal networks in response to external stimuli, with applications in many brain areas. However, when dealing with…

Disordered Systems and Neural Networks · Physics 2020-11-17 Gabriel Mahuas , Giulio Isacchini , Olivier Marre , Ulisse Ferrari , Thierry Mora