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A synaptic theory of Working Memory (WM) has been developed in the last decade as a possible alternative to the persistent spiking paradigm. In this context, we have developed a neural mass model able to reproduce exactly the dynamics of…

Neurons and Cognition · Quantitative Biology 2025-05-29 Halgurd Taher , Alessandro Torcini , Simona Olmi

Memory is a complex phenomenon that involves several distinct mechanisms. These mechanisms operate at different spatial and temporal levels. This chapter focuses on the theoretical framework and the mathematical models that have been…

Neurons and Cognition · Quantitative Biology 2021-12-22 Stefano Fusi

Working memory often appears to exceed its basic span by organizing items into compact representations called chunks. Chunking can be learned over time for familiar inputs; however, it can also arise spontaneously for novel stimuli. Such…

Neurons and Cognition · Quantitative Biology 2025-09-19 Weishun Zhong , Mikhail Katkov , Misha Tsodyks

We investigate the integration of human-like working memory constraints into the Transformer architecture and implement several cognitively inspired attention variants, including fixed-width windows based and temporal decay based attention…

Computation and Language · Computer Science 2026-04-24 Pranava Madhyastha , Dagmar Adamcova

In this work we study, analytically and employing Monte Carlo simulations, the influence of the competition between several activity-dependent synaptic processes, such as short-term synaptic facilitation and depression, on the maximum…

Neurons and Cognition · Quantitative Biology 2010-07-23 Jorge F. Mejias , Joaquin J. Torres

In asymptotic regimes, both in time and space (network size), the derivation of network capacity results is grossly simplified by brushing aside queueing behavior in non-Jackson networks. This simplifying double-limit model, however, lends…

Performance · Computer Science 2013-08-02 Florin Ciucu , Ramin Khalili , Yuming Jiang , Liu Yang , Yong Cui

Performance limitations in visual short-term memory (VSTM) tasks have traditionally been explained in terms of resource or capacity limitations. It has been claimed, for example, that VSTM possesses a limited amount of cognitive or neural…

Neurons and Cognition · Quantitative Biology 2014-07-03 A. Emin Orhan , Robert A. Jacobs

Competition between synapses arises in some forms of correlation-based plasticity. Here we propose a game theory-inspired model of synaptic interactions whose dynamics is driven by competition between synapses in their weak and strong…

Disordered Systems and Neural Networks · Physics 2011-10-19 Ajaz Ahmad Bhat , Gaurang Mahajan , Anita Mehta

Multimodal foundation models (MFMs) have demonstrated significant success in tasks such as visual captioning, question answering, and image-text retrieval. However, these models face inherent limitations due to their finite internal…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Xingjian Diao , Chunhui Zhang , Weiyi Wu , Zhongyu Ouyang , Peijun Qing , Ming Cheng , Soroush Vosoughi , Jiang Gui

Theories and models of working memory (WM) were at least since the mid-1990s dominated by the persistent activity hypothesis. The past decade has seen rising concerns about the shortcomings of sustained activity as the mechanism for…

Neurons and Cognition · Quantitative Biology 2023-04-14 Anders Lansner , Florian Fiebig , Pawel Herman

Cortical sensory neurons are known to be highly variable, in the sense that responses evoked by identical stimuli often change dramatically from trial to trial. The origin of this variability is uncertain, but it is usually interpreted as…

Neurons and Cognition · Quantitative Biology 2007-05-23 Gleb Basalyga , Emilio Salinas

In this paper we present a simple microscopic stochastic model describing short term plasticity within a large homogeneous network of interacting neurons. Each neuron is represented by its membrane potential and by the residual calcium…

Probability · Mathematics 2020-01-29 Antonio Galves , Eva Löcherbach , Christophe Pouzat , Errico Presutti

The distinct timescales of synaptic plasticity and neural activity dynamics play an important role in the brain's learning and memory systems. Activity-dependent plasticity reshapes neural circuit architecture, determining spontaneous and…

Neurons and Cognition · Quantitative Biology 2023-06-30 Heather L Cihak , Zachary P Kilpatrick

Localized persistent neural activity can encode delayed estimates of continuous variables. Common experiments require that subjects store and report the feature value (e.g., orientation) of a particular cue (e.g., oriented bar on a screen)…

Neurons and Cognition · Quantitative Biology 2024-08-01 Heather L Cihak , Zachary P Kilpatrick

Understanding the memory capacity of neural networks remains a challenging problem in implementing artificial intelligence systems. In this paper, we address the notion of capacity with respect to Hopfield networks and propose a dynamic…

Neural and Evolutionary Computing · Computer Science 2017-09-19 Saarthak Sarup , Mingoo Seok

When an action potential is transmitted to a postsynaptic neuron, a small change in the postsynaptic neuron's membrane potential occurs. These small changes, known as a postsynaptic potentials (PSPs), are highly variable, and current models…

Neurons and Cognition · Quantitative Biology 2015-07-14 Laurence Aitchison , Peter E. Latham

We investigate from a computational perspective the efficiency of the Willshaw synaptic update rule in the context of familiarity discrimination, a binary-answer, memory-related task that has been linked through psychophysical experiments…

Neurons and Cognition · Quantitative Biology 2012-08-01 João Sacramento , Andreas Wichert

Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well…

Neurons and Cognition · Quantitative Biology 2018-01-24 Ran Rubin , L. F. Abbott , Haim Sompolinsky

A neural correlate of parametric working memory is a stimulus specific rise in neuron firing rate that persists long after the stimulus is removed. Network models with local excitation and broad inhibition support persistent neural…

Neurons and Cognition · Quantitative Biology 2013-10-15 Zachary P. Kilpatrick , Bard Ermentrout , Brent Doiron

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

Neurons and Cognition · Quantitative Biology 2017-10-10 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian
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