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The parametric optimization for the ultrasound computed tomography system is introduced. It is hypothesized that the pulse characteristic directly affects the information present in the reconstructed profile. The ultrasound excitation modes…

Medical Physics · Physics 2024-08-13 Ankur Kumar , Mayank Goswami

For centuries researchers have used sound to monitor and study wildlife. Traditionally, conservationists have identified species by ear; however, it is now common to deploy audio recording technology to monitor animal and ecosystem sounds.…

Sound · Computer Science 2021-03-15 C. Chalmers , P. Fergus , S. Wich , S. N. Longmore

Proteins are the main workhorses of biological functions in a cell, a tissue, or an organism. Identification and quantification of proteins in a given sample, e.g. a cell type under normal/disease conditions, are fundamental tasks for the…

Computational Engineering, Finance, and Science · Computer Science 2017-10-10 Ngoc Hieu Tran , Zachariah Levine , Lei Xin , Baozhen Shan , Ming Li

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

Biomolecules · Quantitative Biology 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

An efficient despeckling method using a quantum-inspired adaptive threshold function is presented for reducing noise of ultrasound images. In the first step, the ultrasound image is decorrelated by an spectrum equalization procedure due to…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Hamid Reza Shahdoosti

Two-dimensional mass spectrometry (2D MS) is a method for tandem mass spectrometry that enables the correlation between precursor and fragment ions without the need for ion isolation. On a Fourier transform ion cyclotron resonance mass…

Objective measures of image quality generally operate by comparing pixels of a "degraded" image to those of the original. Relative to human observers, these measures are overly sensitive to resampling of texture regions (e.g., replacing one…

Computer Vision and Pattern Recognition · Computer Science 2021-01-25 Keyan Ding , Kede Ma , Shiqi Wang , Eero P. Simoncelli

While there are many different methods for peak detection, no automatic methods for marking peak boundaries to calculate area under the curve (AUC) and signal-to-noise ratio (SNR) estimation exist. An algorithm for the automation of liquid…

Quantitative Methods · Quantitative Biology 2026-01-16 Florian Rupprecht , Sören Enge , Kornelius Schmidt , Wei Gao , Clemens Kirschbaum , Robert Miller

Mass spectrometry based clinical proteomics has emerged as a powerful tool for highthroughput protein profiling and biomarker discovery. Recent improvements in mass spectrometry technology have boosted the potential of proteomic studies in…

Methodology · Statistics 2016-02-10 Alexia Kakourou , Werner Vach , Simone Nicolardi , Yuri van der Burgt , Bart Mertens

Ultrasound imaging is a commonly used modality for several diagnostic and therapeutic procedures. However, the diagnosis by ultrasound relies heavily on the quality of images assessed manually by sonographers, which diminishes the…

Image and Video Processing · Electrical Eng. & Systems 2023-07-10 Deepak Raina , Dimitrios Ntentia , SH Chandrashekhara , Richard Voyles , Subir Kumar Saha

Identification of nearly all proteins in a system using data-dependent acquisition (DDA) mass spectrometry has become routine for simple organisms, such as bacteria and yeast. Still, quantification of the identified proteins may be a…

Quantitative Methods · Quantitative Biology 2019-01-21 Jesse G. Meyer

In ultrasound (US) imaging, various types of adaptive beamforming techniques have been investigated to improve the resolution and contrast-to-noise ratio of the delay and sum (DAS) beamformers. Unfortunately, the performance of these…

Image and Video Processing · Electrical Eng. & Systems 2020-02-25 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

Compressed image quality assessment plays an important role in image services, especially in image compression applications, which can be utilized as a guidance to optimize image processing algorithms. In this paper, we propose an objective…

Image and Video Processing · Electrical Eng. & Systems 2019-05-17 Xinfeng Zhang , Sam Kwong , C. -C. Jay Kuo

Mass spectrometry-based metabolomic analysis depends upon the identification of spectral peaks by their mass and retention time. Statistical analysis that follows the identification currently relies on one main peak of each compound.…

Quantitative Methods · Quantitative Biology 2014-03-20 Tommi Suvitaival , Simon Rogers , Samuel Kaski

Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine…

Quantitative Methods · Quantitative Biology 2023-03-14 Michael J. MacCoss , Javier Alfaro , Meni Wanunu , Danielle A. Faivre , Nikolai Slavov

Automatic speech quality assessment has become increasingly important as modern speech generation systems continue to advance, while human listening tests remain costly, time-consuming, and difficult to scale. Most existing learning-based…

Human physiology and pathology arise from the coordinated interactions of diverse single cells. However, analyzing single cells has been limited by the low sensitivity and throughput of analytical methods. DNA sequencing has recently made…

Quantitative Methods · Quantitative Biology 2020-06-23 Nikolai Slavov

The ability to develop or evolve software or software-based systems/services with defined and guaranteed quality in a predictable way is becoming increasingly important. Essential - though not exclusive - prerequisites for this are the…

Software Engineering · Computer Science 2014-01-10 Adam Trendowicz , Michael Kläs , Constanza Lampasona , Jürgen Münch , Christian Körner , Matthias Saft

Frequency estimation from measurements corrupted by noise is a fundamental challenge across numerous engineering and scientific fields. Among the pivotal factors shaping the resolution capacity of any frequency estimation technique are…

Signal Processing · Electrical Eng. & Systems 2024-09-23 Sampath Kumar Dondapati , Omkar Nitsure , Satish Mulleti

Multidimensional NMR spectroscopy is one of the basic tools for determining the structure of biomolecules. Unfortunately, the resolution of the spectra is often limited by inter-nuclear couplings. This limitation cannot be overcome by…