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Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…
Hippocampal atrophy in Alzheimer's disease (AD) is asymmetric and spatially inhomogeneous. While extensive work has been done on volume and shape analysis of atrophy of the hippocampus in AD, less attention has been given to hippocampal…
Increasing effort in brain image analysis has been dedicated to early diagnosis of Alzheimer's disease (AD) based on neuroimaging data. Most existing studies have been focusing on binary classification problems, e.g., distinguishing AD…
Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…
Deep learning has shown outstanding performance in identifying intricate structures in complex high-dimensional data, especially in the domain of computer vision. The application of deep learning to early detection and automated…
Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…
Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…
Early detection is crucial to prevent the progression of Alzheimer's disease (AD). Thus, specialists can begin preventive treatment as soon as possible. They demand fast and precise assessment in the diagnosis of AD in the earliest and…
Being the most commonly known neurodegeneration, Alzheimer's Disease (AD) is annually diagnosed in millions of patients. The present medical scenario still finds the exact diagnosis and classification of AD through neuroimaging data as a…
The prospect of future treatment warrants the development of cost-effective screening for Alzheimer's disease (AD). A promising candidate in this regard is electroencephalography (EEG), as it is one of the most economic imaging modalities.…
Alzheimer's disease is the most common cause of dementia, yet difficult to accurately diagnose without the use of invasive techniques, particularly at the beginning of the disease. This work addresses the classification and analysis of…
We propose a novel framework for Alzheimer's disease (AD) detection using brain MRIs. The framework starts with a data augmentation method called Brain-Aware Replacements (BAR), which leverages a standard brain parcellation to replace…
Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…
Label propagation is a popular technique for anatomical segmentation. In this work, we propose a novel deep framework for label propagation based on non-local label fusion. Our framework, named CompareNet, incorporates subnets for both…
Alzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently, diagnosing it at an earlier stage will…
The development of statistical approaches for the joint modelling of the temporal changes of imaging, biochemical, and clinical biomarkers is of paramount importance for improving the understanding of neurodegenerative disorders, and for…
We propose a disease classification model, called the QC-SPHARM, for the early detection of the Alzheimer's Disease (AD). The proposed QC-SPHARM can distinguish between normal control (NC) subjects and AD patients, as well as between…
Alzheimer's is a brain disease that gets worse over time and affects memory, thinking, and behavior. Alzheimer's disease (AD) can be treated and managed if it is diagnosed early, which can slow the progression of symptoms and improve…
We propose a method to predict the subject-specific longitudinal progression of brain structures extracted from baseline MRI, and evaluate its performance on Alzheimer's disease data. The disease progression is modeled as a trajectory on a…
Alzheimer's disease and Frontotemporal dementia are common forms of neurodegenerative dementia. Behavioral alterations and cognitive impairments are found in the clinical courses of both diseases and their differential diagnosis is…