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Gene-sharing networks provide a powerful framework to study the evolution of viruses and mobile genetic elements. These bipartite networks, which link genes to the genomes that contain them, exhibit characteristic degree distributions: a…

Populations and Evolution · Quantitative Biology 2026-04-16 Jaime Iranzo , Pedro Jódar , Eugene V. Koonin , Susanna Manrubia , José A. Cuesta

The Third-Generation in DNA sequencing has emerged in the last few years using new technologies that allow the production of long-read sequences. Applications of the Third-Generation sequencing enable real-time and on-site data production,…

Populations and Evolution · Quantitative Biology 2019-02-26 Hyunjin Shim

We introduce and train distributed neural architectures (DNA) in vision and language domains. DNAs are initialized with a proto-architecture that consists of (transformer, MLP, attention, etc.) modules and routers. Any token (or patch) can…

Machine Learning · Computer Science 2025-06-30 Aditya Cowsik , Tianyu He , Andrey Gromov

Various Graph Neural Networks (GNNs) have been successful in analyzing data in non-Euclidean spaces, however, they have limitations such as oversmoothing, i.e., information becomes excessively averaged as the number of hidden layers…

Machine Learning · Computer Science 2024-01-23 Jaeyoon Sim , Sooyeon Jeon , InJun Choi , Guorong Wu , Won Hwa Kim

Neural networks and evolutionary computation have a rich intertwined history. They most commonly appear together when an evolutionary algorithm optimises the parameters and topology of a neural network for reinforcement learning problems,…

Neural and Evolutionary Computing · Computer Science 2016-04-15 Alexander W. Churchill , Siddharth Sigtia , Chrisantha Fernando

The classification of DNA sequences is a key research area in bioinformatics as it enables researchers to conduct genomic analysis and detect possible diseases. In this paper, three state-of-the-art algorithms, namely Convolutional Neural…

Other Quantitative Biology · Quantitative Biology 2020-11-03 Xiangxie Zhang , Ben Beinke , Berlian Al Kindhi , Marco Wiering

Network data are ubiquitous in modern machine learning, with tasks of interest including node classification, node clustering and link prediction. A frequent approach begins by learning an Euclidean embedding of the network, to which…

Machine Learning · Statistics 2023-05-18 Andrew Davison , Morgane Austern

Viruses are submicroscopic agents that can infect all kinds of lifeforms and use their hosts' living cells to replicate themselves. Despite having some of the simplest genetic structures among all living beings, viruses are highly…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Niloy Sikder , Md. Al-Masrur Khan , Anupam Kumar Bairagi , Mehedi Masud , Jun Jiat Tiang , Abdullah-Al Nahid

We present network embedding algorithms that capture information about a node from the local distribution over node attributes around it, as observed over random walks following an approach similar to Skip-gram. Observations from…

Machine Learning · Computer Science 2021-03-23 Benedek Rozemberczki , Carl Allen , Rik Sarkar

This work studies the problem of learning under both large datasets and large-dimensional feature space scenarios. The feature information is assumed to be spread across agents in a network, where each agent observes some of the features.…

Multiagent Systems · Computer Science 2020-05-26 Bicheng Ying , Kun Yuan , Ali H. Sayed

Understanding genetic variation, e.g., through mutations, in organisms is crucial to unravel their effects on the environment and human health. A fundamental characterization can be obtained by solving the haplotype assembly problem, which…

Genomics · Quantitative Biology 2022-10-25 Hansheng Xue , Vaibhav Rajan , Yu Lin

Graph neural networks (GNNs) have become increasingly popular for classification tasks on graph-structured data. Yet, the interplay between graph topology and feature evolution in GNNs is not well understood. In this paper, we focus on…

Machine Learning · Computer Science 2023-10-27 Vignesh Kothapalli , Tom Tirer , Joan Bruna

Deep convolutional networks have proven to be very successful in learning task specific features that allow for unprecedented performance on various computer vision tasks. Training of such networks follows mostly the supervised learning…

Machine Learning · Computer Science 2015-06-22 Alexey Dosovitskiy , Philipp Fischer , Jost Tobias Springenberg , Martin Riedmiller , Thomas Brox

The ICTV develops, refines and maintains a universal virus taxonomy; Order is the highest taxon in the branching hierarchy of recognised viral taxa. Historically, ICTV (sub)committees have classified viruses on the basis of morphological…

Genomics · Quantitative Biology 2018-09-12 T. Wang , M. Herbster , I. S. Mian

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Motivated by observations in sequence data of herpesviruses, we introduce a multi-locus model for the joint evolution of different genotypes in a virus population that is distributed across a population of hosts. In the model, virus…

Populations and Evolution · Quantitative Biology 2025-09-24 Raphael Eichhorn , Cornelia Pokalyuk

Reconstructing components of a genomic mixture from data obtained by means of DNA sequencing is a challenging problem encountered in a variety of applications including single individual haplotyping and studies of viral communities.…

Genomics · Quantitative Biology 2019-11-14 Ziqi Ke , Haris Vikalo

Graph-based machine learning methods are useful tools in the identification and prediction of variation in genetic data. In particular, the comprehension of phenotypic effects at the cellular level is an accelerating research area in…

Quantitative Methods · Quantitative Biology 2024-12-06 Nandini Gadhia , Michalis Smyrnakis , Po-Yu Liu , Damer Blake , Melanie Hay , Anh Nguyen , Dominic Richards , Dong Xia , Ritesh Krishna

With different genomes available, unsupervised learning algorithms are essential in learning genome-wide biological insights. Especially, the functional characterization of different genomes is essential for us to understand lives. In this…

Genomics · Quantitative Biology 2015-08-04 Ka-Chun Wong , Yue Li , Zhaolei Zhang

Feature selection that selects an informative subset of variables from data not only enhances the model interpretability and performance but also alleviates the resource demands. Recently, there has been growing attention on feature…

Neural and Evolutionary Computing · Computer Science 2023-03-15 Zahra Atashgahi , Xuhao Zhang , Neil Kichler , Shiwei Liu , Lu Yin , Mykola Pechenizkiy , Raymond Veldhuis , Decebal Constantin Mocanu
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