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The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…

Quantitative Methods · Quantitative Biology 2021-09-21 Pingjun Chen , Muhammad Aminu , Siba El Hussein , Joseph D. Khoury , Jia Wu

In this paper we present a new H(div)-conforming unfitted finite element method for the mixed Poisson problem which is robust in the cut configuration and preserves conservation properties of body-fitted finite element methods. The key is…

Numerical Analysis · Mathematics 2024-09-04 Christoph Lehrenfeld , Tim van Beeck , Igor Voulis

This paper employs a localized orthogonal decomposition (LOD) method with $H^1$ interpolation for solving the multiscale elliptic problem. This method does not need any assumptions on scale separation. We give a priori error estimate for…

Numerical Analysis · Mathematics 2024-11-04 Tao Yu , Xingye Yue

This article deals with solving partial differential equations with the finite element method on hybrid non-conforming hexahedral-tetrahedral meshes. By non-conforming, we mean that a quadrangular face of a hexahedron can be connected to…

Computational Geometry · Computer Science 2016-05-10 Maxence Reberol , Bruno Lévy

We summarise three applications of the obstacle problem to membrane contact, elastoplastic torsion and cavitation modelling, and show how the resulting models can be solved using mixed finite elements. It is challenging to construct fixed…

Numerical Analysis · Mathematics 2026-01-28 Tom Gustafsson

This paper proposes a new hybrid high-order discretization for the biharmonic problem and the corresponding eigenvalue problem. The discrete ansatz space includes degrees of freedom in $n-2$ dimensional submanifolds (e.g., nodal values in…

Numerical Analysis · Mathematics 2026-04-06 Yizhou Liang , Ngoc Tien Tran

Finite element codes typically use data structures that represent unstructured meshes as collections of cells, faces, and edges, each of which require associated coordinate systems. One then needs to store how the coordinate system of each…

Numerical Analysis · Mathematics 2021-02-16 Rainer Agelek , Michael Anderson , Wolfgang Bangerth , William Barth

Hybrid High-Order methods for elliptic diffusion problems have been originally formulated for loads in the Lebesgue space $L^2(\Omega)$. In this paper we devise and analyze a variant thereof, which is defined for any load in the dual…

Numerical Analysis · Mathematics 2019-05-01 Alexandre Ern , Pietro Zanotti

In this paper we consider a class of unfitted finite element methods for scalar elliptic problems. These so-called CutFEM methods use standard finite element spaces on a fixed unfitted triangulation combined with the Nitsche technique and a…

Numerical Analysis · Mathematics 2022-12-26 Sven Gross , Arnold Reusken

We derive a priori error estimates for Nitsche's method applied to elliptic problems on approximate domains. Such approximations arise, for example, in unfitted finite element methods, data-driven simulations, and evolving domain problems,…

Numerical Analysis · Mathematics 2026-04-02 Mats G. Larson , Karl Larsson , Shantiram Mahata

Interface problems have long been a major focus of scientific computing, leading to the development of various numerical methods. Traditional mesh-based methods often employ time-consuming body-fitted meshes with standard discretization…

Numerical Analysis · Mathematics 2023-08-09 Xurong Chi , Jingrun Chen , Zhouwang Yang

Unstructured meshes are among the most versatile approaches for capturing non-canonical geometries in fluid dynamics simulations. Despite this, most high-fidelity first-principles phase-change models are developed and applied on structured…

Computational Physics · Physics 2026-04-17 Jan Kren , Bojan Ničeno , Yohei Sato

We present a new method for two-material Lagrangian hydrodynamics, which combines the Shifted Interface Method (SIM) with a high-order Finite Element Method. Our approach relies on an exact (or sharp) material interface representation, that…

Numerical Analysis · Mathematics 2023-09-22 Nabil M. Atallah , Ketan Mittal , Guglielmo Scovazzi , Vladimir Z. Tomov

An interface/boundary-unfitted eXtended hybridizable discontinuous Galerkin (X-HDG) method of arbitrary order is proposed for linear elasticity interface problems on unfitted meshes with respect to the interface and domain boundary. The…

Numerical Analysis · Mathematics 2021-02-16 Yihui Han , Xiao-Ping Wang , Xiaoping Xie

In a recent work [10], we have introduced a pressure-robust Hybrid High-Order method for the numerical solution of the incompressible Navier-Stokes equations on matching simplicial meshes. Pressure-robust methods are characterized by error…

Numerical Analysis · Mathematics 2026-01-22 Daniel Castanon Quiroz , Daniele A. Di Pietro

We obtain new integral representations, expressed as contour integrals in the complex Fourier plane, for the solution of fully nonhomogeneous interface problems for the linearized Cahn-Hilliard equation with arbitrary initial data on the…

Analysis of PDEs · Mathematics 2026-05-20 Andreas Chatziafratis , Alain Miranville , Tohru Ozawa

Multigrid solvers for hierarchical hybrid grids (HHG) have been proposed to promote the efficient utilization of high performance computer architectures. These HHG meshes are constructed by uniformly refining a relatively coarse fully…

Numerical Analysis · Mathematics 2023-08-25 Matthias Mayr , Luc Berger-Vergiat , Peter Ohm , Raymond S. Tuminaro

In this paper, we introduce a novel parallel contact algorithm designed to run efficiently in High-Performance Computing based supercomputers. Particular emphasis is put on its computational implementation in a multiphysics finite element…

Computational Engineering, Finance, and Science · Computer Science 2022-08-02 G. Guillamet , M. Rivero , M. Zavala-Aké , M. Vázquez , G. Houzeaux , S. Oller

This work introduces the High-Order Hermite Optimization (HOHO) method, an open-loop discrete adjoint method for quantum optimal control. Our method is the first of its kind to efficiently compute exact (discrete) gradients when using…

Numerical Analysis · Mathematics 2026-01-30 Spencer Lee , Daniel Appelo

Maxwell interface problems are of great importance in many electromagnetic applications. Unfitted mesh methods are especially attractive in 3D computation as they can circumvent generating complex 3D interface-fitted meshes. However, many…

Numerical Analysis · Mathematics 2022-05-30 Long Chen , Ruchi Guo , Jun Zou