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Nuclear magnetic resonance signal dynamics as described by the Bloch equations are highly complex and often are without closed form solutions. This is especially the case for quantitative magnetic resonance fingerprinting (MRF) scans in…

Medical Physics · Physics 2020-10-05 Nikolai J. Mickevicius , Andrew S. Nencka , Eric S. Paulson

Magnetic Resonance Fingerprinting (MRF) has emerged as a promising quantitative imaging technique within the field of Magnetic Resonance Imaging (MRI), offers comprehensive insights into tissue properties by simultaneously acquiring…

Image and Video Processing · Electrical Eng. & Systems 2024-10-11 Chaoguang Gong , Yue Hu , Peng Li , Lixian Zou , Congcong Liu , Yihang Zhou , Yanjie Zhu , Dong Liang , Haifeng Wang

Purpose: To develop a method for optimizing pulsed saturation transfer MR fingerprinting (ST MRF) acquisition. Methods: The Cram\'er-Rao bound (CRB) for variance assessment was employed on Bloch-McConnell-based simulated signals, followed…

Medical Physics · Physics 2025-10-21 Nikita Vladimirov , Moritz Zaiss , Or Perlman

Magnetic Resonance Fingerprinting (MRF) leverages transient-state signal dynamics generated by the tunable acquisition parameters, making the design of an optimal, robust sequence a complex, high-dimensional sequential decision problem,…

Machine Learning · Computer Science 2025-11-26 Shenjun Zhong , Zhifeng Chen , Zhaolin Chen

Magnetic Resonance Fingerprinting (MRF) is a method to extract quantitative tissue properties such as T1 and T2 relaxation rates from arbitrary pulse sequences using conventional magnetic resonance imaging hardware. MRF pulse sequences have…

Magnetic Resonance (MR) Fingerprinting is an emerging multi-parametric quantitative MR imaging technique, for which image reconstruction methods utilizing low-rank and subspace constraints have achieved state-of-the-art performance.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Hengfa Lu , Huihui Ye , Lawrence L. Wald , Bo Zhao

This paper proposes a statistical framework to optimize and evaluate the MR parameter $T_1$ and $T_2$ mapping capabilities for quantitative MRI relaxometry approaches. This analysis explores the intrinsic MR parameter estimate precision per…

Signal Processing · Electrical Eng. & Systems 2020-01-03 Yang Liu , John R. Buck , Shaokuan Zheng

We apply innovative mathematical tools coming from optimal control theory to improve theoretical and experimental techniques in Magnetic Resonance Imaging (MRI). This approach allows us to explore and to experimentally reach the physical…

Quantum Physics · Physics 2017-09-11 E. Van-Reeth , H. Ratiney , M. Lapert , S. J. Glaser , D. Sugny

Magnetic Resonance Fingerprinting (MRF) is a novel technique that simultaneously estimates multiple tissue-related parameters, such as the longitudinal relaxation time T1, the transverse relaxation time T2, off resonance frequency B0 and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Zhe Wang , Hongsheng Li , Qinwei Zhang , Jing Yuan , Xiaogang Wang

MR Fingerprinting is a novel quantitative MR technique that could simultaneously provide multiple tissue property maps. When optimizing MRF scans, modeling undersampling errors and field imperfections in cost functions will make the…

Image and Video Processing · Electrical Eng. & Systems 2021-05-26 Siyuan Hu , Stephen Jordan , Rasim Boyacioglu , Ignacio Rozada , Matthias Troyer , Mark Griswold , Debra McGivney , Dan Ma

Neural networks are increasingly used to estimate parameters in quantitative MRI, in particular in magnetic resonance fingerprinting. Their advantages over the gold standard non-linear least square fitting are their superior speed and their…

Magnetic Resonance Fingerprinting (MRF) is an emerging technology with the potential to revolutionize radiology and medical diagnostics. In comparison to traditional magnetic resonance imaging (MRI), MRF enables the rapid, simultaneous,…

Magnetic Resonance Fingerprinting (MRF) is a new approach to quantitative magnetic resonance imaging that allows simultaneous measurement of multiple tissue properties in a single, time-efficient acquisition. Standard MRF reconstructs…

Computer Vision and Pattern Recognition · Computer Science 2018-12-20 Ilkay Oksuz , Gastao Cruz , James Clough , Aurelien Bustin , Nicolo Fuin , Rene M. Botnar , Claudia Prieto , Andrew P. King , Julia A. Schnabel

The Magnetic Resonance Fingerprinting (MRF) approach aims to estimate multiple MR or physiological parameters simultaneously with a single fast acquisition sequence. Most of the MRF studies proposed so far have used simple MR sequence types…

Neurons and Cognition · Quantitative Biology 2024-07-16 Antoine Barrier , Thomas Coudert , Aurélien Delphin , Benjamin Lemasson , Thomas Christen

Magnetic resonance fingerprinting (MRF) is a technique for quantitative estimation of spin-relaxation parameters from magnetic-resonance data. Most current MRF approaches assume that only one tissue is present in each voxel, which neglects…

The optimal fingerprint method serves as a potent approach for detecting and attributing climate change. However, its experimental validation encounters challenges due to the intricate nature of climate systems. Here, we experimentally…

Atmospheric and Oceanic Physics · Physics 2025-05-13 Jinbo Hu , Hong Yuan , Letian Chen , Nan Zhao , C. P. Sun

Computational models of biophysical tissue properties have been widely used in diffusion MRI (dMRI) research to elucidate the link between microstructural properties and MR signal formation. For brain tissue, the research community has…

Medical Physics · Physics 2019-07-16 Santiago Coelho , Jose M. Pozo , Sune N. Jespersen , Alejandro F. Frangi

In this paper, we propose multi-input multi-output (MIMO) beamforming designs towards joint radar sensing and multi-user communications. We employ the Cram\'er-Rao bound (CRB) as a performance metric of target estimation, under both point…

Signal Processing · Electrical Eng. & Systems 2022-01-26 Fan Liu , Ya-Feng Liu , Ang Li , Christos Masouros , Yonina C. Eldar

The Cram\'er-Rao bound (CRB), a well-known lower bound on the performance of any unbiased parameter estimator, has been used to study a wide variety of problems. However, to obtain the CRB, requires an analytical expression for the…

Machine Learning · Computer Science 2022-10-11 Hai Victor Habi , Hagit Messer , Yoram Bresler

Magnetic Resonance Fingerprinting (MRF) enables simultaneous mapping of multiple tissue parameters such as T1 and T2 relaxation times. The working principle of MRF relies on varying acquisition parameters pseudo-randomly, so that each…

Image and Video Processing · Electrical Eng. & Systems 2020-12-03 Refik Soyak , Ebru Navruz , Eda Ozgu Ersoy , Gastao Cruz , Claudia Prieto , Andrew P. King , Devrim Unay , Ilkay Oksuz
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