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We address the component-based regularisation of a multivariate Generalised Linear Mixed Model (GLMM) in the framework of grouped data. A set Y of random responses is modelled with a multivariate GLMM, based on a set X of explanatory…

Statistics Theory · Mathematics 2019-08-13 Jocelyn Chauvet , Catherine Trottier , Xavier Bry

This paper introduces a method for studying the correlation structure of a range of responses modelled by a multivariate generalised linear mixed model (MGLMM). The methodology requires the existence of clusters of observations and that…

Methodology · Statistics 2021-08-02 Jeanett S. Pelck , Rodrigo Labouriau

Summary: Linear mixed models are a commonly used statistical approach in genome-wide association studies when population structure is present. However, naive permutations to empirically estimate the null distribution of a statistic of…

Genomics · Quantitative Biology 2024-10-03 Saul Pierotti , Tomas Fitzgerald , Ewan Birney

Generalized linear mixed models (GLMM) are used for inference and prediction in a wide range of different applications providing a powerful scientific tool. An increasing number of sources of data are becoming available, introducing a…

Computation · Statistics 2019-03-19 Aliaksandr Hubin , Geir Storvik

Endmember extraction from hyperspectral images aims to identify the spectral signatures of materials present in a scene. Recent studies have shown that self-dictionary methods can achieve high extraction accuracy; however, their high…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Tomohiko Mizutani

This paper investigates Gaussian copula mixture models (GCMM), which are an extension of Gaussian mixture models (GMM) that incorporate copula concepts. The paper presents the mathematical definition of GCMM and explores the properties of…

Machine Learning · Computer Science 2023-05-25 Ke Wan , Alain Kornhauser

Estimation of the number of endmembers existing in a scene constitutes a critical task in the hyperspectral unmixing process. The accuracy of this estimate plays a crucial role in subsequent unsupervised unmixing steps i.e., the derivation…

Computer Vision and Pattern Recognition · Computer Science 2017-03-20 Paris V. Giampouras , Athanasios A. Rontogiannis , Konstantinos D. Koutroumbas

We present generalized additive latent and mixed models (GALAMMs) for analysis of clustered data with responses and latent variables depending smoothly on observed variables. A scalable maximum likelihood estimation algorithm is proposed,…

Methodology · Statistics 2023-03-29 Øystein Sørensen , Anders M. Fjell , Kristine B. Walhovd

In the community of remote sensing, nonlinear mixing models have recently received particular attention in hyperspectral image processing. In this paper, we present a novel nonlinear spectral unmixing method following the recent multilinear…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Qi Wei , Marcus Chen , Jean-Yves Tourneret , Simon Godsill

Modern biomedical datasets are increasingly high dimensional and exhibit complex correlation structures. Generalized Linear Mixed Models (GLMMs) have long been employed to account for such dependencies. However, proper specification of the…

The EM algorithm is a popular tool for maximum likelihood estimation but has not been used much for high-dimensional regularization problems in linear mixed-effects models. In this paper, we introduce the EMLMLasso algorithm, which combines…

Methodology · Statistics 2023-08-04 Daniela C. R. Oliveira , Fernanda L. Schumacher , Victor H. Lachos

Recent strides in interpretable machine learning (ML) research reveal that models exploit undesirable patterns in the data to make predictions, which potentially causes harms in deployment. However, it is unclear how we can fix these…

Recently diversity-inducing regularization methods for latent variable models (LVMs), which encourage the components in LVMs to be diverse, have been studied to address several issues involved in latent variable modeling: (1) how to capture…

Machine Learning · Computer Science 2015-11-24 Pengtao Xie , Yuntian Deng , Eric Xing

Data acquired from multi-channel sensors is a highly valuable asset to interpret the environment for a variety of remote sensing applications. However, low spatial resolution is a critical limitation for previous sensors and the constituent…

Computer Vision and Pattern Recognition · Computer Science 2018-07-17 Savas Ozkan , Berk Kaya , Gozde Bozdagi Akar

General Effect Modelling (GEM) is an umbrella over different methods that utilise effects in the analyses of data with multiple design variables and multivariate responses. To demonstrate the methodology, we here use GEM in gene expression…

We propose Deep Residual Mixture Models (DRMMs), a novel deep generative model architecture. Compared to other deep models, DRMMs allow more flexible conditional sampling: The model can be trained once with all variables, and then used for…

Machine Learning · Computer Science 2021-07-22 Perttu Hämäläinen , Martin Trapp , Tuure Saloheimo , Arno Solin

The Linear Mixing Model (LMM) dominates spectral unmixing for its simplicity, but fails under multiple scattering; existing nonlinear models compensate by applying a fixed regime uniformly across entire scenes. We propose Physics-Guided…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Paula Pacheco , Pablo Granitto , Juan B. Cabral

Selective inference aims at providing valid inference after a data-driven selection of models or hypotheses. It is essential to avoid overconfident results and replicability issues. While significant advances have been made in this area for…

Methodology · Statistics 2025-03-14 Matteo D'Alessandro , Magne Thoresen

Linear mixed models (LMMs) are a powerful and established tool for studying genotype-phenotype relationships. A limiting assumption of LMMs is that the residuals are Gaussian distributed, a requirement that rarely holds in practice.…

Genomics · Quantitative Biology 2014-08-10 Nicolo Fusi , Christoph Lippert , Neil D. Lawrence , Oliver Stegle

Mixtures of Linear Regressions (MLR) is an important mixture model with many applications. In this model, each observation is generated from one of the several unknown linear regression components, where the identity of the generated…

Machine Learning · Computer Science 2020-03-31 Yuanzhi Li , Yingyu Liang